Increase in intracellular protein modification associated with altered lymphocyte functions in autoimmunity
Yang M, Doyle H, Gee R, Aswad D, Mamula M. Increase in intracellular protein modification associated with altered lymphocyte functions in autoimmunity. The FASEB Journal 2006, 20: a964-a964. DOI: 10.1096/fasebj.20.5.a964-a.Peer-Reviewed Original ResearchT cellsT-cell proliferative defectsLupus-like autoimmunityT cell hyperproliferationAutoimmune miceImmune toleranceAutoimmune responseLupus CD4Peripheral circulationLymphocyte functionAntigen stimulationT lymphocytesThymic selectionB cellsBone marrowCell hyperproliferationHyperproliferative responseAutoimmunityLymphocytesMiceProliferative defectPhysiologic pHNon-enzymatic modificationIsoaspartyl proteinsVivo