Featured Publications
Maturing Mycobacterium smegmatis peptidoglycan requires non-canonical crosslinks to maintain shape
Baranowski C, Welsh M, Sham L, Eskandarian H, Lim H, Kieser K, Wagner J, McKinney J, Fantner G, Ioerger T, Walker S, Bernhardt T, Rubin E, Rego E. Maturing Mycobacterium smegmatis peptidoglycan requires non-canonical crosslinks to maintain shape. ELife 2018, 7: e37516. PMID: 30324906, PMCID: PMC6231781, DOI: 10.7554/elife.37516.Peer-Reviewed Original ResearchConceptsPenicillin-binding proteinsAsymmetric polar growthRod-shaped bacteriaPolar growthPolar elongationShape maintenanceCell wallGenetic relationshipsDrug targetsUnusual crosslinksD-transpeptidasesSingle cellsPeptidoglycanCellsCrosslinksProteinMycobacteriaBacteriaPathogensTypes of crosslinksElongationGrowthMaintenanceTarget
2011
PALM and STORM: Unlocking live‐cell super‐resolution
Henriques R, Griffiths C, Rego E, Mhlanga M. PALM and STORM: Unlocking live‐cell super‐resolution. Biopolymers 2011, 95: 322-331. PMID: 21254001, DOI: 10.1002/bip.21586.ChaptersConceptsLive-cell imaging approachesFluorescence light microscopySuper-resolution microscopySingle-molecule levelCellular biologyLocalization microscopy methodsLight microscopySuper-resolution imagingSingle-molecule localization microscopy methodsBiologyMolecule levelFluorescent markersRecent breakthroughsRecent advancesMicroscopy methodsLight microscopeImaging approachDynamic interactionMolecular visualizationPalmImportant toolCellsMicroscopyImportant goalMarkers