2019
Lower antimüllerian hormone is associated with lower oocyte yield but not live-birth rate among women with obesity
Vitek W, Sun F, Baker VL, Styer AK, Christianson MS, Stern JE, Zhang H, Polotsky AJ. Lower antimüllerian hormone is associated with lower oocyte yield but not live-birth rate among women with obesity. American Journal Of Obstetrics And Gynecology 2019, 222: 363.e1-363.e7. PMID: 31589862, PMCID: PMC8022853, DOI: 10.1016/j.ajog.2019.09.046.Peer-Reviewed Original ResearchConceptsNormal body mass indexAntimüllerian hormone levelsLower antimüllerian hormoneBody mass indexLower oocyte yieldLive birth rateAntimüllerian hormoneLow ovarian reserveOocyte yieldMass indexHormone levelsOvarian reserveBody mass index 18.5Low antimüllerian hormone levelsAssisted Reproductive Technology Clinic Outcome Reporting System databaseLower live birth ratesClass 3 obesitySerum antimüllerian hormoneClass 1 obesityClass 2 obesityNumber of oocytesSmall antral folliclesReporting System databaseNormal BMIRetrospective cohort
2018
Vitamin D Deficiency Is Associated With Poor Ovarian Stimulation Outcome in PCOS but Not Unexplained Infertility
Butts SF, Seifer DB, Koelper N, Senapati S, Sammel MD, Hoofnagle AN, Kelly A, Krawetz SA, Santoro N, Zhang H, Diamond MP, Legro RS, Network E. Vitamin D Deficiency Is Associated With Poor Ovarian Stimulation Outcome in PCOS but Not Unexplained Infertility. The Journal Of Clinical Endocrinology & Metabolism 2018, 104: 369-378. PMID: 30085176, PMCID: PMC6300410, DOI: 10.1210/jc.2018-00750.Peer-Reviewed Original ResearchConceptsVitamin D deficiencyPolycystic ovary syndromeD deficiencyEarly pregnancy lossOvarian stimulationUnexplained infertilityLive birthsPregnancy lossDiagnosis of PCOSMultiple Intrauterine GestationsOvarian stimulation outcomesRetrospective cohort studyInvestigation of womenBanked seraPPCOS IICohort studyIntrauterine gestationOvary syndromeInfertile womenInfertility diagnosisPregnant subjectsElevated riskImportant treatmentReproductive outcomesTrial data
2010
The Impact of Environmental and Genetic Factors on Neonatal Late-Onset Sepsis
Bizzarro MJ, Jiang Y, Hussain N, Gruen JR, Bhandari V, Zhang H. The Impact of Environmental and Genetic Factors on Neonatal Late-Onset Sepsis. The Journal Of Pediatrics 2010, 158: 234-238.e1. PMID: 20850766, PMCID: PMC3008342, DOI: 10.1016/j.jpeds.2010.07.060.Peer-Reviewed Original ResearchMeSH KeywordsAge of OnsetBirth WeightBlood-Borne PathogensCohort StudiesConfidence IntervalsCross InfectionEnvironmental ExposureFemaleGenetic Predisposition to DiseaseHospital MortalityHumansInfant, NewbornIntensive Care Units, NeonatalLogistic ModelsMalePrognosisRetrospective StudiesSepsisSurvival RateTime FactorsTwinsTwins, DizygoticTwins, MonozygoticConceptsLate-onset sepsisNewborn intensive care unitIntensive care unitCare unitBirth weightIntensive care unit populationNeonatal late-onset sepsisRetrospective cohort analysisTotal parenteral nutritionRespiratory distress syndromeGenetic factorsLogistic regression analysisMixed-effects logistic regressionNongenetic factorsMixed-effects logistic regression analysisSignificant genetic susceptibilityDistress syndromeParenteral nutritionGestational ageCohort analysisSepsisUnit populationConcordance rateGenetic susceptibilityLogistic regression
2009
Genetic Contribution to Patent Ductus Arteriosus in the Premature Newborn
Bhandari V, Zhou G, Bizzarro MJ, Buhimschi C, Hussain N, Gruen JR, Zhang H. Genetic Contribution to Patent Ductus Arteriosus in the Premature Newborn. Pediatrics 2009, 123: 669-673. PMID: 19171636, PMCID: PMC3161726, DOI: 10.1542/peds.2008-1117.Peer-Reviewed Original ResearchMeSH KeywordsDuctus Arteriosus, PatentFemaleHumansInfant, NewbornInfant, PrematureMaleRetrospective StudiesTwins, DizygoticTwins, MonozygoticConceptsPatent ductus arteriosusDuctus arteriosusRespiratory distress syndromeGestational ageDistress syndromePostmenstrual agePremature newbornsGenetic factorsPreterm patent ductus arteriosusCommon congenital heart diseaseWeeks postmenstrual ageWeeks gestational ageCongenital heart diseaseMixed-effects logistic regressionTwin pairsAntenatal steroidsBronchopulmonary dysplasiaPreterm newbornsSignificant morbidityRetrospective studyOxygen supplementationHeart diseaseMonozygotic twin pairsPremature twinsArteriosus
2006
Genetic Susceptibility to Retinopathy of Prematurity
Bizzarro MJ, Hussain N, Jonsson B, Feng R, Ment LR, Gruen JR, Zhang H, Bhandari V. Genetic Susceptibility to Retinopathy of Prematurity. Pediatrics 2006, 118: 1858-1863. PMID: 17079555, DOI: 10.1542/peds.2006-1088.Peer-Reviewed Original ResearchMeSH KeywordsFemaleGenetic Predisposition to DiseaseHumansInfant, NewbornMaleRetinopathy of PrematurityRetrospective StudiesConceptsRetinopathy of prematuritySupplemental oxygen useLogistic regression analysisGestational ageOxygen useGenetic susceptibilityDuration of ventilationRespiratory distress syndromeLength of stayMixed-effects logistic regression analysisStrong genetic predispositionRegression analysisBronchopulmonary dysplasiaDistress syndromePostmenstrual ageRetrospective studyBirth weightPediatric ophthalmologistsPremature twinsPrematurityRetinopathyGenetic predispositionSignificant covariatesDizygotic twin pairsZygosity dataFamilial and Genetic Susceptibility to Major Neonatal Morbidities in Preterm Twins
Bhandari V, Bizzarro MJ, Shetty A, Zhong X, Page GP, Zhang H, Ment LR, Gruen JR. Familial and Genetic Susceptibility to Major Neonatal Morbidities in Preterm Twins. Pediatrics 2006, 117: 1901-1906. PMID: 16740829, DOI: 10.1542/peds.2005-1414.Peer-Reviewed Original Research
2003
Recurrence of bipolar disorders and major depression
Angst J, Gamma A, Sellaro R, Lavori PW, Zhang H. Recurrence of bipolar disorders and major depression. European Archives Of Psychiatry And Clinical Neuroscience 2003, 253: 236-240. PMID: 14504992, DOI: 10.1007/s00406-003-0437-2.Peer-Reviewed Original ResearchConceptsRecurrence riskBipolar disorderDepressive disorderMajor depressionLifelong prophylactic treatmentRisk of recurrenceState of remissionMajor depressive disorderHigh recurrence riskLong-term trialsProphylactic treatmentDepressive patientsNew episodesBipolar IIRecurrenceSevere typeBP-IIDisordersSignificant gender differencesDepressionRiskGender differencesConstant riskHospitalisationRemissionTree‐based disease classification using protein data
Zhu H, Yu C, Zhang H. Tree‐based disease classification using protein data. Proteomics 2003, 3: 1673-1677. PMID: 12973723, DOI: 10.1002/pmic.200300520.Peer-Reviewed Original Research