2024
Variant Selection and Aggregation of Genetic Association Studies in Precision Medicine
Hu J, Wang S, Zhang H. Variant Selection and Aggregation of Genetic Association Studies in Precision Medicine. ICSA Book Series In Statistics 2024, 423-451. DOI: 10.1007/978-3-031-50690-1_17.Peer-Reviewed Original ResearchAssociation studiesGenetic association studiesPrecision medicineTests of associationHeterogeneous drug responsesDisease risk predictionVariant identificationSignal variantsControl of type I errorDisease riskDrug responseGenomic profilingType I errorRisk predictionGenetic biomarkersVariantsPharmaceutical interventionsMarginal testsAssociation methodAssociationMedicineInterventionIdentificationReplicationDisease
2017
modSaRa: a computationally efficient R package for CNV identification
Xiao F, Niu Y, Hao N, Xu Y, Jin Z, Zhang H. modSaRa: a computationally efficient R package for CNV identification. Bioinformatics 2017, 33: 2384-2385. PMID: 28453611, PMCID: PMC5860124, DOI: 10.1093/bioinformatics/btx212.Peer-Reviewed Original ResearchConceptsComputational complexityHigh computational complexityR packageOptimal computational complexityUser-friendly R packageEfficient R packageSupplementary dataCurrent versionComputational algorithmDesirable accuracyComplexityPackageComprehensive toolCNV identificationDownloadAlgorithmVariant identificationBioinformaticsImplementationTypes of variationRCPPAccuracyIntegrationStepTool