2012
A nonparametric regression method for multiple longitudinal phenotypes using multivariate adaptive splines
Zhu W, Zhang H. A nonparametric regression method for multiple longitudinal phenotypes using multivariate adaptive splines. Frontiers Of Mathematics In China 2012, 8: 731-743. PMID: 25309585, PMCID: PMC4193387, DOI: 10.1007/s11464-012-0256-8.Peer-Reviewed Original Research
2009
A genome-wide association analysis of Framingham Heart Study longitudinal data using multivariate adaptive splines
Zhu W, Cho K, Chen X, Zhang M, Wang M, Zhang H. A genome-wide association analysis of Framingham Heart Study longitudinal data using multivariate adaptive splines. BMC Proceedings 2009, 3: s119. PMID: 20017984, PMCID: PMC2795891, DOI: 10.1186/1753-6561-3-s7-s119.Peer-Reviewed Original ResearchTraits of interestGenome-wide analysisGenome-wide association studiesWide association analysisGenome-wide dataMultivariate adaptive splinesAssociation studiesAssociation analysisGene-environment interactionsTraitsLongitudinal phenotypesGene-environment interaction effectsMasalFramingham Heart StudyPermutation testGenesPhenotype
2008
Modelling gene regulation networks via multivariate adaptive splines.
Chen X, Zhang H. Modelling gene regulation networks via multivariate adaptive splines. Cancer Genomics & Proteomics 2008, 5: 55-62. PMID: 18359980, PMCID: PMC3159687.Peer-Reviewed Original ResearchConceptsRegulatory networksRegulation networkMultivariate adaptive splinesTranscriptional regulation networkTranscriptional regulatory networksGene regulation networksDozens of genomesTranscriptome reprogrammingGene expression time series dataRegulatory motifsHuman genomeTranscription factorsPutative motifsRegulatory functionsRegulatory roleEukaryotesMotifGenomePhysiological conditionsReprogrammingYeastAdaptive splinesIdentification
1999
Analysis of Infant Growth Curves Using Multivariate Adaptive Splines
Zhang H. Analysis of Infant Growth Curves Using Multivariate Adaptive Splines. Biometrics 1999, 55: 452-459. PMID: 11318199, DOI: 10.1111/j.0006-341x.1999.00452.x.Peer-Reviewed Original Research
1997
Multivariate Adaptive Splines for Analysis of Longitudinal Data
Zhang H. Multivariate Adaptive Splines for Analysis of Longitudinal Data. Journal Of Computational And Graphical Statistics 1997, 6: 74-91. DOI: 10.1080/10618600.1997.10474728.Peer-Reviewed Original ResearchSemi-parametric modelNonparametric modelLongitudinal dataMultivariate adaptive splinesGeneral time trendExistence of autocorrelationMultivariate adaptive regression splinesRandom-effects linear modelsAdaptive regression splinesAdaptive splinesCovariance estimationDesign matrixRegression splinesFast algorithmTime trendsIterative procedureGeneral algorithmLinear modelSplinesModel buildingMean curveEstimationAlgorithmData structureEssential features