2018
Complementary Medicine, Refusal of Conventional Cancer Therapy, and Survival Among Patients With Curable Cancers
Johnson SB, Park HS, Gross CP, Yu JB. Complementary Medicine, Refusal of Conventional Cancer Therapy, and Survival Among Patients With Curable Cancers. JAMA Oncology 2018, 4: 1375-1381. PMID: 30027204, PMCID: PMC6233773, DOI: 10.1001/jamaoncol.2018.2487.Peer-Reviewed Original ResearchConceptsConventional cancer treatmentsUse of CMOverall survivalComplementary medicineHormone therapyTreatment delayCharlson-Deyo comorbidity scoreCancer treatmentCancer-accredited centersNational Cancer DatabaseCharacteristics of patientsYear of diagnosisRetrospective observational studyConventional cancer therapiesHigh refusal rateRace/ethnicityNonmetastatic breastComorbidity scorePatient characteristicsCurable cancerEntire cohortColorectal cancerCancer DatabaseInsurance typeObservational study
2017
Use of alternative medicine for cancer and its impact on survival.
Johnson S, Gross C, Park H, Yu J. Use of alternative medicine for cancer and its impact on survival. Journal Of Clinical Oncology 2017, 35: e18175-e18175. DOI: 10.1200/jco.2017.35.15_suppl.e18175.Peer-Reviewed Original ResearchCharlson-Deyo comorbidity scoreConventional cancer treatmentsNational Cancer DatabaseAlternative medicineColorectal cancerCancer treatmentComorbidity scoreCox proportional hazards regressionGreater riskNon-metastatic breastYear of diagnosisAlternative medicine useKaplan-Meier methodSubgroup of patientsAlternative medicine utilizationProportional hazards regressionCancer patient characteristicsDisease-related factorsLog-rank testAnti-cancer treatmentChi-square testPatterns of utilizationHigher socioeconomic statusHormone therapyOverall survival
2016
Postoperative Radiotherapy Patterns of Care and Survival Implications for Medulloblastoma in Young Children
Kann BH, Park HS, Lester-Coll NH, Yeboa DN, Benitez V, Khan AJ, Bindra RS, Marks AM, Roberts KB. Postoperative Radiotherapy Patterns of Care and Survival Implications for Medulloblastoma in Young Children. JAMA Oncology 2016, 2: 1574-1581. PMID: 27491009, DOI: 10.1001/jamaoncol.2016.2547.Peer-Reviewed Original ResearchConceptsPostoperative radiotherapyOverall survivalMultivariable logistic regressionNational Cancer Data BaseLogistic regressionAdjuvant chemotherapy strategyLow facility volumeNational treatment patternsMultivariable Cox regressionLong-term morbidityYear of diagnosisDay of surgeryKaplan-Meier analysisNational database analysisPoor overall survivalLog-rank testYoung childrenAge 3Adjuvant chemotherapyRadiotherapy patternsRadiotherapy utilizationWorse survivalDistant metastasisMultivariable analysisTreatment patterns
2015
Changing practice patterns of Gamma Knife versus linear accelerator-based stereotactic radiosurgery for brain metastases in the US.
Park HS, Wang EH, Rutter CE, Corso CD, Chiang VL, Yu JB. Changing practice patterns of Gamma Knife versus linear accelerator-based stereotactic radiosurgery for brain metastases in the US. Journal Of Neurosurgery 2015, 124: 1018-24. PMID: 26473783, DOI: 10.3171/2015.4.jns1573.Peer-Reviewed Original ResearchConceptsSingle-fraction stereotactic radiosurgeryNon-small cell lung cancerBrain metastasesStereotactic radiosurgeryNational Cancer Data BaseMultivariable logistic regression analysisSingle-fraction SRSLinear accelerator-based stereotactic radiosurgeryAcademic facility typesLimited brain metastasesNSCLC brain metastasesProportion of patientsYear of diagnosisToxicity of treatmentCell lung cancerLogistic regression analysisSRS useWide geographic variationChi-square testComparative effectiveness researchProspective trialIndependent predictorsMultivariable analysisNonclinical factorsRadiosurgery systemThe evolving role of adjuvant radiotherapy for elderly women with early‐stage breast cancer
Rutter CE, Lester-Coll NH, Mancini BR, Corso CD, Park HS, Yeboa DN, Gross CP, Evans SB. The evolving role of adjuvant radiotherapy for elderly women with early‐stage breast cancer. Cancer 2015, 121: 2331-2340. PMID: 25810128, DOI: 10.1002/cncr.29377.Peer-Reviewed Original ResearchConceptsEarly-stage breast cancerER-positive early-stage breast cancerRT useElderly patientsLogistic regression analysisBoost radiotherapyAdjuvant radiotherapyBreast cancerLeukemia Group B (CALGB) 9343 trialPositive early-stage breast cancerNational Cancer Data BaseMultivariable logistic regression analysisAvoidance of radiotherapyLocal control benefitNegative resection marginsYear of diagnosisUse of radiotherapyRegression analysisClinicopathologic covariatesRT detailsOlder patientsOverall survivalHypofractionated radiotherapyResection marginsEvidence-based practice
2014
Increase in the use of lung stereotactic body radiotherapy without a preceding biopsy in the United States
Rutter CE, Corso CD, Park HS, Mancini BR, Yeboa DN, Lester-Coll NH, Kim AW, Decker RH. Increase in the use of lung stereotactic body radiotherapy without a preceding biopsy in the United States. Lung Cancer 2014, 85: 390-394. PMID: 25001510, DOI: 10.1016/j.lungcan.2014.06.013.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancerStereotactic body radiotherapyBody radiotherapyStage I non-small cell lung cancerEarly-stage non-small cell lung cancerStage non-small cell lung cancerMultivariate analysisUse of SBRTLung stereotactic body radiotherapyLogistic regressionNational Cancer DatabasePercentage of patientsYear of diagnosisSmaller tumor sizeCell lung cancerMultivariate logistic regressionMedical inoperabilityMedical comorbiditiesInoperable patientsTumor sizeLung cancerCancer DatabaseEfficacious treatmentSBRT deliveryBiopsy