1986
Sodium and chloride transport in the large intestine of potassium-loaded rats
Budinger M, Foster E, Hayslett J, Binder H. Sodium and chloride transport in the large intestine of potassium-loaded rats. American Journal Of Physiology 1986, 251: g249-g252. PMID: 2426972, DOI: 10.1152/ajpgi.1986.251.2.g249.Peer-Reviewed Original ResearchConceptsPotassium secretionSodium absorptionRat distal colonic mucosaElectroneutral sodium chloride absorptionPotassium loadingNa-K-ATPase activityElectrogenic sodium absorptionDistal colonic mucosaActive potassium secretionPotassium-loaded ratsNet sodium absorptionSodium chloride absorptionActive sodium transportVoltage-clamp conditionsDietary potassiumColonic functionColonic mucosaNet chloride fluxNet sodium fluxJNanetNet sodiumLarge intestineChloride fluxSodium transportIdentical increaseEffect of glucocorticoids on rectal transport in normal subjects and patients with ulcerative colitis.
Sandle G, Hayslett J, Binder H. Effect of glucocorticoids on rectal transport in normal subjects and patients with ulcerative colitis. Gut 1986, 27: 309. PMID: 3699552, PMCID: PMC1433405, DOI: 10.1136/gut.27.3.309.Peer-Reviewed Original ResearchConceptsActive ulcerative colitisInactive ulcerative colitisUlcerative colitisControl subjectsPharmacological dosesIntravenous administrationNet sodiumAcute ulcerative colitisAnti-inflammatory actionEffects of glucocorticoidsNet sodium absorptionColonic sodiumRectal pdAcute increaseAcute effectsColitisHydrocortisone hemisuccinateNormal subjectsPatientsGlucocorticoid hormonesSodium absorptionNet electrolyteGlucocorticoidsSimilar increaseSimilar changes
1985
Evidence that aldosterone influences transport in target tissues by dissimilar mechanisms
Hirsch D, Pace P, Binder H, Hayslett J. Evidence that aldosterone influences transport in target tissues by dissimilar mechanisms. American Journal Of Physiology 1985, 248: f507-f512. PMID: 3985157, DOI: 10.1152/ajprenal.1985.248.4.f507.Peer-Reviewed Original ResearchConceptsProximal colonDistal colonSodium absorptionEffects of hyperaldosteronismSodium-free dietTarget tissuesAction of aldosteroneNet sodium absorptionRat proximal colonTransmural potential differenceAldosterone influencesHormone-induced changesSecondary hyperaldosteronismPotassium secretionControl animalsNet sodiumColonExperimental animalsHyperaldosteronismAldosteroneSodium transportProximal portionElectrolyte transportMicroA xTissue
1983
Role of calcium in the regulation of colonic secretion in the rat
Zimmerman T, Dobbins J, Binder H. Role of calcium in the regulation of colonic secretion in the rat. American Journal Of Physiology 1983, 244: g552-g560. PMID: 6133455, DOI: 10.1152/ajpgi.1983.244.5.g552.Peer-Reviewed Original ResearchConceptsSerosal calciumRole of calciumExtracellular calciumElectrolyte transportNeutral sodium chloride absorptionEffect of bethanecholEffect of theophyllineMuscarinic cholinergic agonistNet sodium absorptionSodium chloride absorptionNet chloride absorptionCalcium-free mediumNeutral NaCl absorptionColonic secretionCholinergic agonistsIntracellular calciumBethanecholNet sodiumRat colonChloride secretionJNanetSodium absorptionChloride absorptionJClnetNaCl absorption