1995
Chloride-dependent Na-H Exchange A NOVEL MECHANISM OF SODIUM TRANSPORT IN COLONIC CRYPTS*
Rajendran V, Geibel J, Binder H. Chloride-dependent Na-H Exchange A NOVEL MECHANISM OF SODIUM TRANSPORT IN COLONIC CRYPTS*. Journal Of Biological Chemistry 1995, 270: 11051-11054. PMID: 7744735, DOI: 10.1074/jbc.270.19.11051.Peer-Reviewed Original ResearchConceptsNa-H exchangeColonic crypt cellsCrypt cellsAcid loadRat distal colonApical membrane vesiclesNovel transport processRate of intracellularDistal colonMM amilorideSodium transportApical membraneGradient stimulationColonic cryptsAmiloride inhibitionSodium movementNovel mechanismOutward gradientCompelling evidenceCellsSodiumUptakePrior studiesColonRecovery
1987
Mechanism of electroneutral sodium chloride absorption in distal colon of the rat
Binder H, Foster E, Budinger M, Hayslett J. Mechanism of electroneutral sodium chloride absorption in distal colon of the rat. Gastroenterology 1987, 93: 449-455. PMID: 3609655, DOI: 10.1016/0016-5085(87)90905-x.Peer-Reviewed Original ResearchConceptsSodium chloride absorptionElectroneutral sodium chloride absorptionNet sodium absorptionNet chloride absorptionDistal colonChloride absorptionSodium absorptionRat distal colonSodium chloride cotransportVoltage-clamp conditionsMM furosemideMM amilorideMucosal bathing solutionChloride transportClamp conditionsColonBathing solutionRatsElectrogenic sodiumMechanism of sodiumAmilorideSodiumAbsence of potassiumCotransportMucosa
1986
Ion transport in proximal colon of the rat. Sodium depletion stimulates neutral sodium chloride absorption.
Foster E, Budinger M, Hayslett J, Binder H. Ion transport in proximal colon of the rat. Sodium depletion stimulates neutral sodium chloride absorption. Journal Of Clinical Investigation 1986, 77: 228-235. PMID: 2418060, PMCID: PMC423331, DOI: 10.1172/jci112281.Peer-Reviewed Original ResearchMeSH Keywords4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic AcidAcetazolamideAmilorideAnimalsBiological Transport, ActiveColonHyperaldosteronismIntestinal AbsorptionIntestinal MucosaIon ChannelsMaleRatsRats, Inbred StrainsSodium ChlorideTheophyllineConceptsMu eq/hSodium-hydrogen exchangeProximal colonSodium depletionSodium absorptionDistal colonNeutral sodium chloride absorptionDistal segmentsAmiloride-sensitive sodium absorptionNet sodium absorptionSodium-depleted ratsRat distal colonSodium chloride absorptionNeutral sodium absorptionHydrogen ion secretionSecondary hyperaldosteronismParallel fallRat colonControl groupMM amilorideMucosal amilorideJNanetColonIon secretionChloride absorption