2008
Ovarian cancer risk is associated with a common variant in the promoter sequence of the mismatch repair gene MLH1
Harley I, Rosen B, Risch HA, Siminovitch K, Beiner ME, McLaughlin J, Sun P, Narod SA. Ovarian cancer risk is associated with a common variant in the promoter sequence of the mismatch repair gene MLH1. Gynecologic Oncology 2008, 109: 384-387. PMID: 18405947, PMCID: PMC3060029, DOI: 10.1016/j.ygyno.2007.11.046.Peer-Reviewed Original ResearchConceptsHereditary non-polyposis colon cancer syndromeInvasive ovarian cancerOvarian cancerMLH1 genePolymorphic variantsOvarian cancer riskColon cancer syndromesMismatch repair genes MLH1Endometrial cancerClear cellsCancer riskCardinal featuresCancer syndromesCancerGenes MLH1Proportion of familiesSignificant riskSyndromeColonCommon variantsRiskEthnic groupsPredisposesHistologyVariants
1997
Perineal talc exposure and risk of ovarian carcinoma
Chang S, Risch H. Perineal talc exposure and risk of ovarian carcinoma. Cancer 1997, 79: 2396-2401. PMID: 9191529, DOI: 10.1002/(sici)1097-0142(19970615)79:12<2396::aid-cncr15>3.0.co;2-m.Peer-Reviewed Original ResearchConceptsOvarian carcinomaTalc exposureFrequency of exposureUnconditional logistic regression methodsTalcum powder useInvasive ovarian carcinomasBorderline significant associationPerineal talc exposureBorderline carcinomaMenstrual historyInvasive carcinomaCarcinoma typesEpidemiologic studiesEpidemiologic investigationsCarcinomaSignificant associationPowder useHistologic sectionsLogistic regression methodRole of talcSignificant riskFurther studiesOnly riskRiskPerineum