Clip Closure Does Not Reduce Risk of Bleeding After Resection of Large Serrated Polyps: Results From a Randomized Trial
Crockett S, Khashab M, Rex D, Grimm I, Moyer M, Rastogi A, Mackenzie T, Pohl H, Consortium L, Al-Kawas F, Antaki F, Aslanian H, Crockett S, Elias P, Elmunzer B, Gill J, Gordon S, Grimm I, Hasan M, Khashab M, Law R, Levenick J, Mackenzie T, Mathew A, Moyer M, Ortiz O, Pellise M, Pleskow D, Pohl H, Rastogi A, von Renteln D, Rex D, Sanaei O. Clip Closure Does Not Reduce Risk of Bleeding After Resection of Large Serrated Polyps: Results From a Randomized Trial. Clinical Gastroenterology And Hepatology 2021, 20: 1757-1765.e4. PMID: 34971811, DOI: 10.1016/j.cgh.2021.12.036.Peer-Reviewed Original ResearchConceptsLarge serrated polypsEndoscopic mucosal resectionPost-procedure bleedingAdenomatous polypsBleeding rateProximal colonSerrated polypsControl groupLarge non-pedunculated polypsLimited clinical trial evidenceOverall serious adverse eventsPost-polypectomy bleeding rateDay of colonoscopyNon-pedunculated polypsSerious adverse eventsClinical trial evidenceRisk of bleedingColorectal cancer precursorsResection baseBleeding riskAdverse eventsMucosal resectionMulticenter trialPrimary outcomeProphylactic clipping