2019
Submissions from the SPRINT Data Analysis Challenge on clinical risk prediction: a cross-sectional evaluation
Jackevicius CA, An J, Ko DT, Ross JS, Angraal S, Wallach JD, Koh M, Song J, Krumholz HM. Submissions from the SPRINT Data Analysis Challenge on clinical risk prediction: a cross-sectional evaluation. BMJ Open 2019, 9: e025936. PMID: 30904868, PMCID: PMC6475140, DOI: 10.1136/bmjopen-2018-025936.Peer-Reviewed Original ResearchConceptsRisk prediction toolsCross-sectional evaluationClinical risk predictionClinical performanceCardiovascular disease historyClinical risk scoreHigh-risk patientsLow-risk patientsClinical prediction toolRisk predictionEfficacy outcomesC-statisticDisease historyInclusion criteriaIndependent reviewersRisk scoreExternal validationPatientsPrediction toolsEfficacyOutcomesSame outcome
2018
Large-Scale Epidemiologic Studies of Cardiovascular Diseases in China Need for Improved Data Collection, Methods, Transparency, and Documentation
Qu H, Lu Y, Gudbranson E, Bucholz EM, Xuan S, Masoudi FA, Spertus JA, Zheng X, Li J, Krumholz HM. Large-Scale Epidemiologic Studies of Cardiovascular Diseases in China Need for Improved Data Collection, Methods, Transparency, and Documentation. Global Heart 2018, 13: 3-12.e4. PMID: 29248362, DOI: 10.1016/j.gheart.2017.07.002.Peer-Reviewed Original Research
2010
Implementation of a Registry for Acute Coronary Syndrome in Resource-Limited Settings: Barriers and Opportunities
Safavi K, Linnander EL, Allam AA, Bradley EH, Krumholz HM. Implementation of a Registry for Acute Coronary Syndrome in Resource-Limited Settings: Barriers and Opportunities. Asia Pacific Journal Of Public Health 2010, 22: 90s-95s. PMID: 20566539, DOI: 10.1177/1010539510373017.Peer-Reviewed Original ResearchConceptsAcute coronary syndromeCardiovascular diseaseCoronary syndromeHealth systemClinical Outcomes RegistryEvidence-based careCause of deathResource limited settingsResource-limited settingsWorld health systemsQuality improvement activitiesMiddle-income countriesOutcomes RegistryHigh-quality treatmentBlame-free cultureClinical registryRegistrySyndromeImprovement activitiesHospitalDiseaseSetting
2007
Comparing Hospital Performance in Door-to-Balloon Time Between the Hospital Quality Alliance and the National Cardiovascular Data Registry
Nallamothu BK, Wang Y, Bradley EH, Ho KK, Curtis JP, Rumsfeld JS, Masoudi FA, Krumholz HM. Comparing Hospital Performance in Door-to-Balloon Time Between the Hospital Quality Alliance and the National Cardiovascular Data Registry. Journal Of The American College Of Cardiology 2007, 50: 1517-1519. PMID: 17919575, DOI: 10.1016/j.jacc.2007.07.010.Peer-Reviewed Original Research
2006
Transfers of Patient Care Between House Staff on Internal Medicine Wards: A National Survey
Horwitz LI, Krumholz HM, Green ML, Huot SJ. Transfers of Patient Care Between House Staff on Internal Medicine Wards: A National Survey. JAMA Internal Medicine 2006, 166: 1173-1177. PMID: 16772243, DOI: 10.1001/archinte.166.11.1173.Peer-Reviewed Original ResearchMeSH KeywordsData CollectionHospital DepartmentsInternal MedicineInternship and ResidencyPatient TransferUnited StatesConceptsTransfer of careInternal medicine residency programsMedicine residency programsPatient careWork-hour regulationsResidency programsResident work hour regulationsInternal medicine wardsMain outcome measuresUS internal medicine residency programsClinical outcomesMedicine wardsPrimary teamOutcome measuresHypothetical patientsSelf-administered surveyResident physiciansCare systemCarePatient informationHouse staffHospitalizationPatientsNational surveyComprehensive transferRelation Between Hospital Specialization With Primary Percutaneous Coronary Intervention and Clinical Outcomes in ST-Segment Elevation Myocardial Infarction
Nallamothu BK, Wang Y, Magid DJ, McNamara RL, Herrin J, Bradley EH, Bates ER, Pollack CV, Krumholz HM. Relation Between Hospital Specialization With Primary Percutaneous Coronary Intervention and Clinical Outcomes in ST-Segment Elevation Myocardial Infarction. Circulation 2006, 113: 222-229. PMID: 16401769, DOI: 10.1161/circulationaha.105.578195.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionElevation myocardial infarctionHospital mortalityBalloon timePPCI volumeFibrinolytic therapyClinical outcomesMyocardial infarctionPrimary percutaneous coronary intervention capabilityPercutaneous coronary intervention capabilityPrimary percutaneous coronary interventionHierarchical multivariable regressionMyocardial infarction 4Hospital-level factorsPercutaneous coronary interventionHospital specializationSTEMI patientsCoronary interventionHighest quartileShorter doorHospital characteristicsNational registryLowest quartileRelative riskMultivariable regression
2005
American College of Cardiology and American Heart Association Methodology for the Selection and Creation of Performance Measures for Quantifying the Quality of Cardiovascular Care
Spertus JA, Eagle KA, Krumholz HM, Mitchell KR, Normand SL. American College of Cardiology and American Heart Association Methodology for the Selection and Creation of Performance Measures for Quantifying the Quality of Cardiovascular Care. Circulation 2005, 111: 1703-1712. PMID: 15811870, DOI: 10.1161/01.cir.0000157096.95223.d7.Peer-Reviewed Original Research
2003
The roles of senior management in quality improvement efforts: what are the key components?
Bradley EH, Holmboe ES, Mattera JA, Roumanis SA, Radford MJ, Krumholz HM. The roles of senior management in quality improvement efforts: what are the key components? Journal Of Healthcare Management 2003, 48: 15-28; discussion 29. PMID: 12592866, DOI: 10.1097/00115514-200301000-00005.Peer-Reviewed Original Research
2001
American College of Cardiology key data elements and definitions for measuring the clinical management and outcomes of patients with acute coronary syndromes
Cannon C, Battler A, Brindis R, Cox J, Ellis S, Every N, Flaherty J, Harrington R, Krumholz H, Simoons M, Van De Werf F, Weintraub W, Mitchell K, Morrisson S, Brindis R, Anderson H, Cannom D, Chitwood W, Cigarroa J, Collins-Nakai R, Ellis S, Gibbons R, Grover F, Heidenreich P, Khandheria B, Knoebel S, Krumholz H, Malenka D, Mark D, Mckay C, Passamani E, Radford M, Riner R, Schwartz J, Shaw R, Shemin R, Van Fossen D, Verrier E, Watkins M, Phoubandith D, Furnelli T. American College of Cardiology key data elements and definitions for measuring the clinical management and outcomes of patients with acute coronary syndromes. Journal Of The American College Of Cardiology 2001, 38: 2114-2130. PMID: 11738323, DOI: 10.1016/s0735-1097(01)01702-8.Peer-Reviewed Original Research
2000
Evaluating Quality of Care for Patients With Heart Failure
Krumholz H, Baker D, Ashton C, Dunbar S, Friesinger G, Havranek E, Hlatky M, Konstam M, Ordin D, Pina I, Pitt B, Spertus J. Evaluating Quality of Care for Patients With Heart Failure. Circulation 2000, 101: e122-40. PMID: 10736303, DOI: 10.1161/01.cir.101.12.e122.Peer-Reviewed Original ResearchAdrenergic beta-AntagonistsAgedAngiotensin-Converting Enzyme InhibitorsAnticoagulantsAspirinAtrial FibrillationData CollectionDigoxinExercise TherapyFee-for-Service PlansHeart FailureHumansInformation ServicesLength of StayOutcome and Process Assessment, Health CarePatient Education as TopicPractice Guidelines as TopicPractice Patterns, Physicians'Quality of Health CareReferral and ConsultationStroke VolumeUnited StatesVentricular Dysfunction, Left
1999
Variations in and correlates of length of stay in academic hospitals among patients with heart failure resulting from systolic dysfunction.
Krumholz HM, Chen YT, Bradford WD, Cerese J. Variations in and correlates of length of stay in academic hospitals among patients with heart failure resulting from systolic dysfunction. The American Journal Of Managed Care 1999, 5: 715-23. PMID: 10538451.Peer-Reviewed Original ResearchConceptsLength of stayCongestive heart failureHeart failureSystolic dysfunctionPatient characteristicsAcademic hospitalCollaborative quality improvement projectIndividual hospitalsAdmission clinical characteristicsRetrospective cohort studyPrincipal discharge diagnosisNumber of patientsQuality improvement projectUniversity HealthSystem ConsortiumCorrelates of lengthHospital stayPeripheral edemaClinical characteristicsCohort studyRenal failureClinical factorsMajor complicationsHospital eventsRegression modelsAtrial fibrillationQuality of care for patients hospitalized with heart failure at academic medical centers
Nohria A, Chen Y, Morton D, Walsh R, Vlasses P, Krumholz H. Quality of care for patients hospitalized with heart failure at academic medical centers. American Heart Journal 1999, 137: 1028-1034. PMID: 10347327, DOI: 10.1016/s0002-8703(99)70358-3.Peer-Reviewed Original ResearchConceptsLeft ventricular ejection fractionCongestive heart failureAcademic medical centerTime of dischargeStandard of careMedical CenterHeart failureACE inhibitorsAssessment of LVEFDiagnosis of CHFDaily weightEnzyme inhibitor therapyRetrospective chart reviewVentricular ejection fractionLarge clinical trialsPatient education guidelinesQuality of careHealth care policyChart reviewDietary counselingHospital dischargeEjection fractionInhibitor therapyTreatment guidelinesMedication compliance
1998
Trends in costs of percutaneous transluminal coronary angioplasty.
Heiat A, Mattera JA, Henry GA, Chen YT, Krumholz HM. Trends in costs of percutaneous transluminal coronary angioplasty. The American Journal Of Managed Care 1998, 4: 1667-74. PMID: 10339099.Peer-Reviewed Original ResearchConceptsPercutaneous transluminal coronary angioplastyTransluminal coronary angioplastyCoronary angioplastyClinical outcomesElective percutaneous transluminal coronary angioplastyYale-New Haven HospitalCatheterization laboratory costsMedical chart reviewGroup of patientsTotal hospital costsLength of stayHospital cost accounting systemChart reviewClinical characteristicsConsecutive patientsAngiographic featuresHospital recordsContrast volumeRetrospective studyPatient populationHospital costsLesion characteristicsStent useCatheterization laboratoryPatient profilesImproving the Quality of Care for Medicare Patients With Acute Myocardial Infarction: Results From the Cooperative Cardiovascular Project
Marciniak TA, Ellerbeck EF, Radford MJ, Kresowik TF, Gold JA, Krumholz HM, Kiefe CI, Allman RM, Vogel RA, Jencks SF. Improving the Quality of Care for Medicare Patients With Acute Myocardial Infarction: Results From the Cooperative Cardiovascular Project. JAMA 1998, 279: 1351-1357. PMID: 9582042, DOI: 10.1001/jama.279.17.1351.Peer-Reviewed Original ResearchMeSH KeywordsAlabamaCardiologyCardiology Service, HospitalConnecticutData CollectionHospital MortalityHospitalsHumansIowaMedicareMyocardial InfarctionPilot ProjectsProfessional Review OrganizationsQuality Assurance, Health CareQuality Indicators, Health CareStatistics, NonparametricSurvival AnalysisUnited StatesWisconsinConceptsAcute myocardial infarctionQuality of careMyocardial infarctionMedicare patientsBeta-blocker useAdministration of aspirinClinical practice guidelinesCooperative Cardiovascular ProjectLength of stayAcute care hospitalsQuality improvement projectQuality Improvement ProgramPilot statesPostinfarction mortalityAspirin useCessation counselingCare hospitalPeer review organizationsMedian lengthInpatient claimsPrincipal diagnosisPractice guidelinesInfarctionPatientsMortality comparisons