2021
Assessment of Concordance and Discordance Among Clinical Studies Posted as Preprints and Subsequently Published in High-Impact Journals
Shi X, Ross JS, Amancharla N, Niforatos JD, Krumholz HM, Wallach JD. Assessment of Concordance and Discordance Among Clinical Studies Posted as Preprints and Subsequently Published in High-Impact Journals. JAMA Network Open 2021, 4: e212110. PMID: 33734411, PMCID: PMC7974637, DOI: 10.1001/jamanetworkopen.2021.2110.Peer-Reviewed Original Research
2020
Non-inferiority trials using a surrogate marker as the primary endpoint: An increasing phenotype in cardiovascular trials
Bikdeli B, Caraballo C, Welsh J, Ross JS, Kaul S, Stone GW, Krumholz HM. Non-inferiority trials using a surrogate marker as the primary endpoint: An increasing phenotype in cardiovascular trials. Clinical Trials 2020, 17: 723-728. PMID: 32838556, PMCID: PMC8088773, DOI: 10.1177/1740774520949157.Peer-Reviewed Original ResearchMeSH KeywordsBiomarkersCardiovascular DiseasesEndpoint DeterminationEquivalence Trials as TopicHumansJournal Impact FactorPhenotypeResearch DesignResearch ReportConceptsNon-inferiority trialPrimary endpointClinical outcome trialsNon-inferiority marginSurrogate markerNon-inferiority designCardiovascular trialsOutcome trialsClinical outcomesDefinitive clinical outcome trialsNon-inferiority criteriaStudy protocolSurrogate outcomesBACKGROUND/Median numberSurrogate endpointsPrimary analysisCardiovascular interventionsCardiovascular medicineTrialsEndpointClinical interpretationOutcomesMarkersInterventionAssessment of Preprint Policies of Top-Ranked Clinical Journals
Massey DS, Opare MA, Wallach JD, Ross JS, Krumholz HM. Assessment of Preprint Policies of Top-Ranked Clinical Journals. JAMA Network Open 2020, 3: e2011127. PMID: 32697320, PMCID: PMC7376388, DOI: 10.1001/jamanetworkopen.2020.11127.Peer-Reviewed Original ResearchMeSH KeywordsCross-Sectional StudiesEditorial PoliciesHumansJournal Impact FactorJournalism, MedicalPeriodicals as TopicPreprints as Topic
2019
Noninferiority Designed Cardiovascular Trials in Highest-Impact Journals
Bikdeli B, Welsh JW, Akram Y, Punnanithinont N, Lee I, Desai NR, Kaul S, Stone G, Ross JS, Krumholz HM. Noninferiority Designed Cardiovascular Trials in Highest-Impact Journals. Circulation 2019, 140: 379-389. PMID: 31177811, PMCID: PMC8416048, DOI: 10.1161/circulationaha.119.040214.Peer-Reviewed Original ResearchMeSH KeywordsCardiovascular DiseasesEquivalence Trials as TopicHumansJournal Impact FactorPeriodicals as TopicConceptsNoninferiority marginNoninferiority trialCardiovascular trialsAllocation concealmentLower riskOpen labelHazard ratioRelative riskMethodological qualityProportion of trialsIndependent reviewersRisk differenceNew England JournalNoninferiorityHigh-impact journalsNew interventionsTrialsCohortDiscrepant resultsProtocol analysisTime trendsRiskTreatInterventionFactors
2018
Age of Data at the Time of Publication of Contemporary Clinical Trials
Welsh J, Lu Y, Dhruva SS, Bikdeli B, Desai NR, Benchetrit L, Zimmerman CO, Mu L, Ross JS, Krumholz HM. Age of Data at the Time of Publication of Contemporary Clinical Trials. JAMA Network Open 2018, 1: e181065-e181065. PMID: 30646100, PMCID: PMC6324269, DOI: 10.1001/jamanetworkopen.2018.1065.Peer-Reviewed Original ResearchMeSH KeywordsCross-Sectional StudiesJournal Impact FactorPublishingRandomized Controlled Trials as TopicResearch DesignTime FactorsConceptsClinical trialsFinal data collectionParticipant enrollmentInternal medicineMultivariable linear regression analysisFirst participant enrollmentPrimary end pointMultivariable regression analysisContemporary clinical trialsClinical trial dataJAMA Internal MedicineRegression analysisCross-sectional analysisTime of publicationMedian timeTrial characteristicsOutcome measuresMAIN OUTCOMENew England JournalClinical practiceLinear regression analysisTrial dataEnd pointTrial resultsTrials
2015
Association Between Journal Citation Distribution and Impact Factor A Novel Application of the Gini Coefficient
Nuti SV, Ranasinghe I, Murugiah K, Shojaee A, Li SX, Krumholz HM. Association Between Journal Citation Distribution and Impact Factor A Novel Application of the Gini Coefficient. Journal Of The American College Of Cardiology 2015, 65: 1711-1712. PMID: 25908079, PMCID: PMC5459371, DOI: 10.1016/j.jacc.2014.12.071.Peer-Reviewed Original ResearchPoorly Cited Articles in Peer-Reviewed Cardiovascular Journals from 1997 to 2007
Ranasinghe I, Shojaee A, Bikdeli B, Gupta A, Chen R, Ross JS, Masoudi FA, Spertus JA, Nallamothu BK, Krumholz HM. Poorly Cited Articles in Peer-Reviewed Cardiovascular Journals from 1997 to 2007. Circulation 2015, 131: 1755-1762. PMID: 25812573, PMCID: PMC4560203, DOI: 10.1161/circulationaha.114.015080.Peer-Reviewed Original Research
2014
Reporting of Results in ClinicalTrials.gov and High-Impact Journals
Becker JE, Krumholz HM, Ben-Josef G, Ross JS. Reporting of Results in ClinicalTrials.gov and High-Impact Journals. JAMA 2014, 311: 1063-1065. PMID: 24618969, PMCID: PMC3979514, DOI: 10.1001/jama.2013.285634.Peer-Reviewed Original Research
2012
Sharing of clinical trial data among trialists: a cross sectional survey
Rathi V, Dzara K, Gross CP, Hrynaszkiewicz I, Joffe S, Krumholz HM, Strait KM, Ross JS. Sharing of clinical trial data among trialists: a cross sectional survey. The BMJ 2012, 345: e7570. PMID: 23169870, PMCID: PMC3502744, DOI: 10.1136/bmj.e7570.Peer-Reviewed Original ResearchMeSH KeywordsClinical Trials as TopicCross-Sectional StudiesInformation DisseminationJournal Impact FactorSurveys and QuestionnairesConceptsClinical trial dataTrial dataGeneral medical journalsHigh-impact general medical journalsCross-sectional surveyDe-identified dataMedical journalsClinical trialsTrial fundersClinical trialistsSectional surveyTrialistsTrialsInvestigatorsExperiences of sharingPrevalence of dataPotential respondentsHigh impact factorAppropriate data usePrevalenceRespondentsCirculation
Krumholz HM, Spertus JA. Circulation. Circulation Cardiovascular Quality And Outcomes 2012, 5: e28-e32. PMID: 22811507, DOI: 10.1161/circoutcomes.112.967653.Peer-Reviewed Original Research