2020
Timely estimation of National Admission, readmission, and observation-stay rates in medicare patients with acute myocardial infarction, heart failure, or pneumonia using near real-time claims data
Li SX, Wang Y, Lama SD, Schwartz J, Herrin J, Mei H, Lin Z, Bernheim SM, Spivack S, Krumholz HM, Suter LG. Timely estimation of National Admission, readmission, and observation-stay rates in medicare patients with acute myocardial infarction, heart failure, or pneumonia using near real-time claims data. BMC Health Services Research 2020, 20: 733. PMID: 32778098, PMCID: PMC7416804, DOI: 10.1186/s12913-020-05611-w.Peer-Reviewed Original ResearchLarge-scale evidence generation and evaluation across a network of databases (LEGEND): assessing validity using hypertension as a case study
Schuemie MJ, Ryan PB, Pratt N, Chen R, You SC, Krumholz HM, Madigan D, Hripcsak G, Suchard MA. Large-scale evidence generation and evaluation across a network of databases (LEGEND): assessing validity using hypertension as a case study. Journal Of The American Medical Informatics Association 2020, 27: 1268-1277. PMID: 32827027, PMCID: PMC7481033, DOI: 10.1093/jamia/ocaa124.Peer-Reviewed Original ResearchPrinciples of Large-scale Evidence Generation and Evaluation across a Network of Databases (LEGEND)
Schuemie MJ, Ryan PB, Pratt N, Chen R, You SC, Krumholz HM, Madigan D, Hripcsak G, Suchard MA. Principles of Large-scale Evidence Generation and Evaluation across a Network of Databases (LEGEND). Journal Of The American Medical Informatics Association 2020, 27: 1331-1337. PMID: 32909033, PMCID: PMC7481029, DOI: 10.1093/jamia/ocaa103.Peer-Reviewed Original ResearchConceptsNetwork of databasesLarge-scale Evidence GenerationObservational Health Data SciencesObservational health care databasesHealth Data SciencesHealth care dataElectronic health recordsData sciencePublication biasPatient-level informationGeneric overviewHealth recordsMethods addressAforementioned concernsHealth care databasesAnalytic codeNetworkNew paradigmSuch dataHackingEvidence generationDissemination of evidenceHypertension treatmentResidual confoundingAdministrative claims
2010
Implementation of a Registry for Acute Coronary Syndrome in Resource-Limited Settings: Barriers and Opportunities
Safavi K, Linnander EL, Allam AA, Bradley EH, Krumholz HM. Implementation of a Registry for Acute Coronary Syndrome in Resource-Limited Settings: Barriers and Opportunities. Asia Pacific Journal Of Public Health 2010, 22: 90s-95s. PMID: 20566539, DOI: 10.1177/1010539510373017.Peer-Reviewed Original ResearchConceptsAcute coronary syndromeCardiovascular diseaseCoronary syndromeHealth systemClinical Outcomes RegistryEvidence-based careCause of deathResource limited settingsResource-limited settingsWorld health systemsQuality improvement activitiesMiddle-income countriesOutcomes RegistryHigh-quality treatmentBlame-free cultureClinical registryRegistrySyndromeImprovement activitiesHospitalDiseaseSetting
2005
Low-to-Moderate Alcohol Intake and Health Status in Heart Failure Patients
Salisbury AC, House JA, Conard MW, Krumholz HM, Spertus JA. Low-to-Moderate Alcohol Intake and Health Status in Heart Failure Patients. Journal Of Cardiac Failure 2005, 11: 323-328. PMID: 15948080, DOI: 10.1016/j.cardfail.2004.11.009.Peer-Reviewed Original ResearchConceptsKansas City Cardiomyopathy QuestionnaireModerate alcohol intakeHealth statusHF hospitalizationAlcohol intakeAlcohol abstinenceBaseline Kansas City Cardiomyopathy QuestionnaireShort Form-12 scoresComplete alcohol abstinenceHeart failure guidelinesMulticenter observational studyHeart failure patientsModerate alcohol consumptionSF-12 scoresKCCQ scoresHF outpatientsHF patientsFailure patientsMultivariable analysisBaseline differencesObservational studyModerate drinkersAlcohol consumptionSimilar outcomesAlcohol use