Increased Mortality among Survivors of Myocardial Infarction with Kidney Dysfunction: the Contribution of Gaps in the use of Guideline-Based Therapies
Peterson PN, Ambardekar AV, Jones PG, Krumholz HM, Schelbert E, Spertus JA, Rumsfeld JS, Masoudi FA. Increased Mortality among Survivors of Myocardial Infarction with Kidney Dysfunction: the Contribution of Gaps in the use of Guideline-Based Therapies. BMC Cardiovascular Disorders 2009, 9: 29. PMID: 19586550, PMCID: PMC2716301, DOI: 10.1186/1471-2261-9-29.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedFemaleGlomerular Filtration RateHumansKaplan-Meier EstimateKidney DiseasesMaleMiddle AgedMyocardial InfarctionPractice Guidelines as TopicProportional Hazards ModelsProspective StudiesRegistriesRisk AssessmentSeverity of Illness IndexSurvivorsTime FactorsTreatment OutcomeUnited StatesConceptsGlomerular filtration rateAcute myocardial infarctionGuideline-based medical therapyGuideline-based therapyMedical therapyKidney dysfunctionMyocardial infarctionUse of guidelinesEligible patientsRenal dysfunctionHazard ratioCox regressionPathophysiological abnormalitiesClinical variablesKidney diseaseFiltration rateNovel therapiesUS CentersHigh mortalityPatientsTherapyFurther adjustmentMortalityDysfunctionTreatment factors