2020
Changes in Functional Status and Health-Related Quality of Life in Older Adults After Surgical, Interventional, or Medical Management of Acute Myocardial Infarction
Mori M, Djulbegovic M, Hajduk A, Holland ML, Krumholz HM, Chaudhry SI. Changes in Functional Status and Health-Related Quality of Life in Older Adults After Surgical, Interventional, or Medical Management of Acute Myocardial Infarction. Seminars In Thoracic And Cardiovascular Surgery 2020, 33: 72-81. PMID: 32439546, PMCID: PMC7983308, DOI: 10.1053/j.semtcvs.2020.05.001.Peer-Reviewed Original ResearchConceptsCoronary artery bypass graftPercutaneous coronary interventionAcute myocardial infarctionPhysical component scaleMedical managementFunctional statusOlder patientsMyocardial infarctionArtery bypass graftHealth-related qualityAge 75 yearsPatient-centered outcomesRisk of declinePredictors of declineQuality of lifeUnadjusted incidenceCoronary interventionADL declineCardiac surgeryMedical therapyBypass graftSF-12Multivariable modelHRQoLPatients
2011
Angina frequency after myocardial infarction and quality of life in older versus younger adults: The Prospective Registry Evaluating Myocardial Infarction: Event and Recovery study
Longmore RB, Spertus JA, Alexander KP, Gosch K, Reid KJ, Masoudi FA, Krumholz HM, Rich MW. Angina frequency after myocardial infarction and quality of life in older versus younger adults: The Prospective Registry Evaluating Myocardial Infarction: Event and Recovery study. American Heart Journal 2011, 161: 631-638. PMID: 21392621, DOI: 10.1016/j.ahj.2010.12.005.Peer-Reviewed Original ResearchConceptsSeattle Angina QuestionnaireCoronary artery diseaseYounger patientsAngina controlAngina frequencyOlder patientsArtery diseaseMyocardial infarctionChronic coronary artery diseaseSAQ angina frequency scoreYoung adultsAngina frequency scoreGreater HRQL improvementsHealth-related qualityQuality of lifeBaseline HRQLHRQL improvementResidual anginaAngina QuestionnaireProspective registryStable patientsMI survivorsRecent MISurvivors increasesHRQL
2008
The influence of age on health status outcomes after acute myocardial infarction
Ho PM, Eng MH, Rumsfeld JS, Spertus JA, Peterson PN, Jones PG, Peterson ED, Alexander KP, Havranek EP, Krumholz HM, Masoudi FA. The influence of age on health status outcomes after acute myocardial infarction. American Heart Journal 2008, 155: 855-861. PMID: 18440332, DOI: 10.1016/j.ahj.2007.11.032.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionYears of ageSurvivors of AMIHealth status outcomesOlder patientsBetter HRQLHigh mortalityMyocardial infarctionStatus outcomesSeattle Angina QuestionnaireBaseline health statusHealth-related qualityNumber of patientsInfluence of ageAngina burdenBaseline anginaAngina QuestionnaireAngina symptomsClinical characteristicsProspective cohortYounger patientsMultivariable analysisRisk factorsSpectrum of ageHRQL
2006
Impact of Chronic Kidney Disease on Health-Related Quality-of-Life Improvement After Coronary Artery Bypass Surgery
Parikh CR, Coca SG, Smith GL, Vaccarino V, Krumholz HM. Impact of Chronic Kidney Disease on Health-Related Quality-of-Life Improvement After Coronary Artery Bypass Surgery. JAMA Internal Medicine 2006, 166: 2014-2019. PMID: 17030836, DOI: 10.1001/archinte.166.18.2014.Peer-Reviewed Original ResearchConceptsSevere chronic kidney diseaseChronic kidney diseasePhysical functionMH scorePF scoresKidney diseaseMedical Outcomes Trust Short FormAdvanced chronic kidney diseaseCoronary artery bypass surgeryLife outcomesCoronary artery bypassPrimary end pointArtery bypass surgeryHealth-related qualityCoronary artery diseaseMH subscalesArtery bypassCKD stageBypass surgeryArtery diseaseHealth SurveyMean changeStage 0Mean decreaseCABGSocial support and change in health-related quality of life 6 months after coronary artery bypass grafting
Barry LC, Kasl SV, Lichtman J, Vaccarino V, Krumholz HM. Social support and change in health-related quality of life 6 months after coronary artery bypass grafting. Journal Of Psychosomatic Research 2006, 60: 185-193. PMID: 16439272, DOI: 10.1016/j.jpsychores.2005.06.080.Peer-Reviewed Original ResearchConceptsHealth-related qualityCoronary artery bypassPhysical functioningMental healthArtery bypassSF-36 subscale scoresAge 65.7 yearsLife 6 monthsStepwise linear regression analysisSocial supportFirst CABGHospital dischargeProspective cohortClinical presentationLinear regression analysisInstrumental supportChange scoresSubscale scoresMonthsSocial support variablesRegression analysisBypassHealthIntervention effortsEmotional support
2004
Age, functional capacity, and health-related quality of life in patients with heart failure
Masoudi FA, Rumsfeld JS, Havranek EP, House JA, Peterson ED, Krumholz HM, Spertus JA, Consortium F. Age, functional capacity, and health-related quality of life in patients with heart failure. Journal Of Cardiac Failure 2004, 10: 368-373. PMID: 15470645, DOI: 10.1016/j.cardfail.2004.01.009.Peer-Reviewed Original ResearchConceptsKansas City Cardiomyopathy QuestionnaireHealth-related qualityHeart failureYounger patientsFunctional statusNYHA classOlder patientsBetter HRQLFunctional limitationsWalk distanceNew York Heart Association classificationMulticenter prospective cohort studyOlder personsBaseline NYHA classWorse NYHA classProspective cohort studySignificant functional limitationsBaseline functional limitationsSignificant physical disabilityImportance of treatmentBaseline HRQLMultivariable adjustmentCohort studyAssociation classificationHRQL
2000
Impact of Smoking on Health-Related Quality of Life After Percutaneous Coronary Revascularization
Taira D, Seto T, Ho K, Krumholz H, Cutlip D, Berezin R, Kuntz R, Cohen D. Impact of Smoking on Health-Related Quality of Life After Percutaneous Coronary Revascularization. Circulation 2000, 102: 1369-1374. PMID: 10993854, DOI: 10.1161/01.cir.102.12.1369.Peer-Reviewed Original ResearchConceptsGeneral health perceptionSmoking statusHealth perceptionMedical Outcomes Study SF-36 questionnaireSymptomatic coronary artery diseaseMental healthRole-physical functioningImpact of smokingLate myocardial infarctionHealth-related qualityPercutaneous coronary revascularizationSF-36 questionnaireCoronary artery diseaseMulticenter clinical trialTime of PTCAQuality of lifeHRQoL improvementContinued smokingCoronary revascularizationBaseline characteristicsArtery diseaseIndex procedureSmoking cessationPhysical functionMyocardial infarctionAssociation of patients’ perception of health status and exercise electrocardiogram, myocardial perfusion imaging, and ventricular function measures
Mattera J, de Leon C, Wackers F, Williams C, Wang Y, Krumholz H. Association of patients’ perception of health status and exercise electrocardiogram, myocardial perfusion imaging, and ventricular function measures. American Heart Journal 2000, 140: 409-418. PMID: 10966538, DOI: 10.1067/mhj.2000.108518.Peer-Reviewed Original ResearchConceptsGeneral health perceptionHealth-related qualityPhysical functioningHealth perceptionMyocardial perfusion imagingHealth statusExercise testingPerfusion imagingMedical Outcomes Study Short Form SurveyPatients' health-related qualityShort Form SurveyAssociation of patientGeneral health statusImportant outcome measureSuccess of treatmentConsecutive patientsSF-36Metabolic equivalentsNoninvasive testingExercise testPatient outcomesIndividual patientsOutcome measuresForm SurveyPatient's viewpoint
1999
Economics, health-related quality of life, and cost-effectiveness methods for the TACTICS (Treat Angina with Aggrastat® [tirofiban] and Determine Cost of Therapy with Invasive or Conservative Strategy)–TIMI 18 trial
Weintraub W, Culler S, Kosinski A, Becker E, Mahoney E, Burnette J, Spertus J, Feeny D, Cohen D, Krumholz H, Ellis S, Demopoulos L, Robertson D, Boccuzzi S, Barr E, Cannon C. Economics, health-related quality of life, and cost-effectiveness methods for the TACTICS (Treat Angina with Aggrastat® [tirofiban] and Determine Cost of Therapy with Invasive or Conservative Strategy)–TIMI 18 trial. The American Journal Of Cardiology 1999, 83: 317-322. PMID: 10072215, DOI: 10.1016/s0002-9149(98)00860-1.Peer-Reviewed Original ResearchConceptsQuality-adjusted life yearsHealth Utilities IndexLife yearsHealth-related qualityCost-effectiveness methodsNon-Q-wave myocardial infarctionUtility indexCost-effectiveness analysisDetermine CostImpact of invasiveEconomic formsUB92 formulationHealth care costsUnstable anginaRelative value scaleMedicare conversion factorMyocardial infarctionMedicare fee scheduleDepartmental costsEconomicsExpensive formFee scheduleTACTICS-TIMI 18Care costsOutcomes of patients
1998
A Population-Based Perspective of Changes in Health-Related Quality of Life After Myocardial Infarction in Older Men and Women
de Leon C, Krumholz H, Vaccarino V, Williams C, Glass T, Berkman L, Kas S. A Population-Based Perspective of Changes in Health-Related Quality of Life After Myocardial Infarction in Older Men and Women. Journal Of Clinical Epidemiology 1998, 51: 609-616. PMID: 9674668, DOI: 10.1016/s0895-4356(98)00037-7.Peer-Reviewed Original ResearchConceptsMyocardial infarctionMI patientsSelf-rated healthSocial functioningEffects of MICHD risk factorsWomen 65 yearsBurden of illnessHealth-related qualityRecent myocardial infarctionPopulation-based perspectiveQuality of lifePooled logistic regression modelLogistic regression modelsLife-related outcomesRisk factorsPhysical functioningMI periodDepressive symptomsOlder livingOlder menPatientsBivariate analysisLife outcomesSubstantial proportion
1997
Health after coronary stenting or balloon angioplasty: Results from the Stent Restenosis Study
Krumholz H, Cohen D, Williams C, Baim D, Brinker J, Cabin H, Heuser R, Hirshfeld J, Leon M, Moses J, Savage M, Cleman M. Health after coronary stenting or balloon angioplasty: Results from the Stent Restenosis Study. American Heart Journal 1997, 134: 337-344. PMID: 9327686, DOI: 10.1016/s0002-8703(97)70065-6.Peer-Reviewed Original ResearchConceptsStent Restenosis StudyCoronary stentingBalloon angioplastyRestenosis StudyDuke Activity Status IndexPalmaz-Schatz coronary stentingCanadian Cardiovascular Society classificationPalmaz-Schatz coronary stent implantationPercutaneous transluminal coronary angioplastyU.S. clinical sitesLong-term HRQoLForm Health SurveyHealth-related qualityMedical Outcomes StudyTransluminal coronary angioplastyCoronary stent implantationConventional balloon angioplastyDisease-specific measuresAngiographic restenosisConventional angioplastyIschemic eventsBodily painConsecutive patientsCoronary angioplastyCardiovascular perspective
1996
Changes in health after elective percutaneous coronary revascularization. A comparison of generic and specific measures.
Krumholz HM, McHorney CA, Clark L, Levesque M, Baim DS, Goldman L. Changes in health after elective percutaneous coronary revascularization. A comparison of generic and specific measures. Medical Care 1996, 34: 754-9. PMID: 8709657, DOI: 10.1097/00005650-199608000-00003.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAgedAngioplasty, Balloon, CoronaryBostonElective Surgical ProceduresFemaleHealth StatusHealth SurveysHumansMaleMental HealthMiddle AgedOutcome Assessment, Health CareProspective StudiesQuality of LifeReproducibility of ResultsSick RoleSurveys and QuestionnairesTime FactorsConceptsElective percutaneous coronary revascularizationCanadian Cardiovascular Society classificationPercutaneous coronary revascularizationHealth-related qualityCoronary revascularizationSpecific Activity ScaleRole limitationsElective percutaneous transluminal coronary angioplastyPercutaneous transluminal coronary angioplastyForm Health SurveyMedical Outcomes StudyTransluminal coronary angioplastyGeneral health perceptionRole physical scaleSF-36 Role Physical scaleSF-36 physical functioning scaleSF-36 measuresPhysical functioning scaleGeneral mental healthPhysical health problemsEmotional health problemsSymptomatic patientsCoronary angioplastyPhysical functioningSociety classification