2022
Analysis of Hospital-Level Readmission Rates and Variation in Adverse Events Among Patients With Pneumonia in the United States
Wang Y, Eldridge N, Metersky ML, Rodrick D, Faniel C, Eckenrode S, Mathew J, Galusha DH, Tasimi A, Ho SY, Jaser L, Peterson A, Normand ST, Krumholz HM. Analysis of Hospital-Level Readmission Rates and Variation in Adverse Events Among Patients With Pneumonia in the United States. JAMA Network Open 2022, 5: e2214586. PMID: 35639379, PMCID: PMC9157270, DOI: 10.1001/jamanetworkopen.2022.14586.Peer-Reviewed Original ResearchConceptsRisk-standardized readmission ratesMedicare Patient Safety Monitoring SystemCause readmission rateAdverse eventsReadmission ratesHigh riskHospital-level readmission ratesHigher patient riskHospital adverse eventsAdverse event dataCross-sectional studyHospital performanceIndex hospitalizationMedian ageHospital characteristicsMedical recordsReadmission dataPatient riskHospital careMAIN OUTCOMEPneumoniaHospital levelPatientsReadmissionGreater risk
2016
Return to Work After Acute Myocardial Infarction
Dreyer RP, Xu X, Zhang W, Du X, Strait KM, Bierlein M, Bucholz EM, Geda M, Fox J, D'Onofrio G, Lichtman JH, Bueno H, Spertus JA, Krumholz HM. Return to Work After Acute Myocardial Infarction. Circulation Cardiovascular Quality And Outcomes 2016, 9: s45-s52. PMID: 26908859, PMCID: PMC4771977, DOI: 10.1161/circoutcomes.115.002611.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionMyocardial infarctionYoung AMI Patients (VIRGO) studyPrevious coronary diseaseYoung populationPatients' sociodemographic characteristicsSex differencesMedical record abstractionMultivariable regression analysisCoronary diseasePatient characteristicsYounger patientsRecord abstractionPatient interviewsHealth characteristicsPsychosocial factorsWorse recoverySociodemographic characteristicsHealth measuresGreater riskYoung womenPhysical healthPatient studiesHigher likelihoodYoung men
2010
Do Self- or Parent-Reported Dietary, Physical Activity, and Sedentary Behaviors Predict Worsening Obesity in Children?
Dorsey KB, Mauldon M, Magraw R, Yu S, Krumholz HM. Do Self- or Parent-Reported Dietary, Physical Activity, and Sedentary Behaviors Predict Worsening Obesity in Children? The Journal Of Pediatrics 2010, 157: 566-571. PMID: 20542293, PMCID: PMC2936814, DOI: 10.1016/j.jpeds.2010.04.062.Peer-Reviewed Original ResearchConceptsBMI z-scoreRisk factorsZ-scoreFamily historySedentary behaviorPhysical activityRisk behaviorsRoutine healthcare visitsPhysical activity behaviorHealthcare visitsObese patientsDiabetes mellitusObese childrenAcanthosis nigricansMedical recordsPediatric cliniciansBMI valuesObesityRandom effects regression analysisGreater riskActivity behaviorOverweightPatientsRegression analysisVisits
2005
Admission Glucose and Mortality in Elderly Patients Hospitalized With Acute Myocardial Infarction
Kosiborod M, Rathore SS, Inzucchi SE, Masoudi FA, Wang Y, Havranek EP, Krumholz HM. Admission Glucose and Mortality in Elderly Patients Hospitalized With Acute Myocardial Infarction. Circulation 2005, 111: 3078-3086. PMID: 15939812, DOI: 10.1161/circulationaha.104.517839.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionGlucose levelsHigh glucose levelsMyocardial infarctionAdmission glucoseElderly patientsHyperglycemic patientsMortality riskElderly acute myocardial infarction patientsAcute myocardial infarction patientsAdmission glucose levelsMyocardial infarction patientsSimilar glucose levelsGreater mortality riskNondiabetic patientsMultivariable adjustmentDiabetic patientsInfarction patientsElevated glucosePatientsDiabetesGreater riskInfarctionMortality resultsMortality
2002
Cardiac outcomes after myocardial infarction in elderly patients with diabetes mellitus.
Chyun D, Vaccarino V, Murillo J, Young LH, Krumholz HM. Cardiac outcomes after myocardial infarction in elderly patients with diabetes mellitus. American Journal Of Critical Care 2002, 11: 504-19. PMID: 12425401, DOI: 10.4037/ajcc2002.11.6.504.Peer-Reviewed Original ResearchConceptsRecurrent myocardial infarctionInsulin-treated diabetes mellitusDiabetes mellitusMyocardial infarctionElderly patientsHeart failureVentricular functionComorbid conditionsClinical findingsIndex myocardial infarctionPoor ventricular functionInsulin-treated diabetesAcute myocardial infarctionCardiac outcomesPoor outcomeMedical recordsMellitusInfarctionMedicare beneficiariesPatientsGreater riskInsulinMortalityRiskOutcomesDepression and Risk of Heart Failure Among the Elderly: A Prospective Community-Based Study
Williams SA, Kasl SV, Heiat A, Abramson JL, Krumholz HM, Vaccarino V. Depression and Risk of Heart Failure Among the Elderly: A Prospective Community-Based Study. Psychosomatic Medicine 2002, 64: 6-12. PMID: 11818580, DOI: 10.1097/00006842-200201000-00002.Peer-Reviewed Original ResearchConceptsHeart failureIndependent risk factorCoronary heart diseaseImpact of depressionEffect of depressionHospital admissionComorbidity factorsCox regressionProspective CommunityElderly menFunctional statusHeart diseaseRisk factorsElderly womenBaseline differencesEpidemiological studiesFunctional limitationsGreater riskUnderlying causeDepressionIncidenceEstablished PopulationsCommunity sampleDepressed participantsWomen
2001
Sex differences in 2-year mortality after hospital discharge for myocardial infarction.
Vaccarino V, Krumholz H, Yarzebski J, Gore J, Goldberg R. Sex differences in 2-year mortality after hospital discharge for myocardial infarction. Annals Of Internal Medicine 2001, 134: 173-81. PMID: 11177329, DOI: 10.7326/0003-4819-134-3-200102060-00007.Peer-Reviewed Original ResearchConceptsMyocardial infarctionHigh mortality rateHospital dischargeMortality rateMedical historyHigher long-term mortality ratesCommunity-based prospective cohort studyLong-term mortality ratesGreater riskMortality 2 yearsProspective cohort studyDemographic characteristicsAcute myocardial infarctionYears of ageLower mortality rateSex differencesHospital mortalityClinical characteristicsCohort studyOlder patientsAge womenCommunity hospitalLower riskInfarctionPatients
2000
Long-term Outcome of Myocardial Infarction in Women and Men: A Population Perspective
Vaccarino V, Berkman LF, Krumholz HM. Long-term Outcome of Myocardial Infarction in Women and Men: A Population Perspective. American Journal Of Epidemiology 2000, 152: 965-973. PMID: 11092438, DOI: 10.1093/aje/152.10.965.Peer-Reviewed Original ResearchConceptsMyocardial infarctionSurvival advantageImpact of MIMultivariable-adjusted hazard ratiosWomen's survival advantageLong-term mortalityLong-term outcomesPresence of MIAbsence of MISurvival of personsProportional hazards modelPopulation perspectiveTime-dependent covariablesFatal infarctionHazard ratioSame followElderly cohortMI hospitalizationMI casesHazards modelGreater riskInfarctionWomenMenSurvival