2016
Association of Guideline-Based Admission Treatments and Life Expectancy After Myocardial Infarction in Elderly Medicare Beneficiaries
Bucholz EM, Butala NM, Normand SL, Wang Y, Krumholz HM. Association of Guideline-Based Admission Treatments and Life Expectancy After Myocardial Infarction in Elderly Medicare Beneficiaries. Journal Of The American College Of Cardiology 2016, 67: 2378-2391. PMID: 27199062, PMCID: PMC5097252, DOI: 10.1016/j.jacc.2016.03.507.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAgedAspirinFemaleFollow-Up StudiesGuideline AdherenceHospitalizationHumansLife ExpectancyMaleMedicareMyocardial InfarctionPercutaneous Coronary InterventionPlatelet Aggregation InhibitorsPractice Guidelines as TopicThrombolytic TherapyTime-to-TreatmentUnited StatesConceptsAcute myocardial infarctionPrimary percutaneous coronary interventionGuideline-based therapyYears of lifeAdmission therapyLife expectancyMyocardial infarctionMedicare beneficiariesCox proportional hazards regressionAcute reperfusion therapyLate survival benefitReceipt of aspirinPercutaneous coronary interventionLong-term outcomesProportional hazards regressionCooperative Cardiovascular ProjectElderly Medicare beneficiariesDose-response relationshipAssociation of GuidelineShort life expectancyLonger life expectancyReperfusion therapyCoronary interventionD2B timeElderly patientsUnderweight, Markers of Cachexia, and Mortality in Acute Myocardial Infarction: A Prospective Cohort Study of Elderly Medicare Beneficiaries
Bucholz EM, Krumholz HA, Krumholz HM. Underweight, Markers of Cachexia, and Mortality in Acute Myocardial Infarction: A Prospective Cohort Study of Elderly Medicare Beneficiaries. PLOS Medicine 2016, 13: e1001998. PMID: 27093615, PMCID: PMC4836735, DOI: 10.1371/journal.pmed.1001998.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overBody Mass IndexCachexiaComorbidityFemaleFrail ElderlyGeriatric AssessmentHospital MortalityHumansInsurance BenefitsKaplan-Meier EstimateMaleMedicareMyocardial InfarctionNutrition AssessmentNutritional StatusPrevalencePrognosisProportional Hazards ModelsProspective StudiesRisk AssessmentRisk FactorsThinnessTime FactorsUnited StatesConceptsLower body mass indexNormal weight patientsBody mass indexAcute myocardial infarctionUnderweight patientsWeight patientsSubset of patientsHigh riskFrailty measuresLaboratory markersMyocardial infarctionMedicare beneficiariesNutritional statusCox proportional hazards regressionUnderweight body mass indexMarkers of cachexiaLong-term mortalityProspective cohort studyCohort-based studyMeasures of frailtyProportional hazards regressionCooperative Cardiovascular ProjectElderly Medicare beneficiariesImportant risk factorSignificant chronic illness
2010
Thirty-Day Outcomes in Medicare Patients With Heart Failure at Heart Transplant Centers
Hummel SL, Pauli NP, Krumholz HM, Wang Y, Chen J, Normand SL, Nallamothu BK. Thirty-Day Outcomes in Medicare Patients With Heart Failure at Heart Transplant Centers. Circulation Heart Failure 2010, 3: 244-252. PMID: 20061519, DOI: 10.1161/circheartfailure.109.884098.Peer-Reviewed Original ResearchConceptsHeart transplant centersRisk-standardized readmission ratesRisk-standardized mortality ratesTransplant centersStandardized mortality ratioHeart failureTransplant hospitalsReadmission ratesMortality rateStandardized readmission ratioMortality ratioMedicare patientsReadmission ratiosMean standardized mortality ratioThirty-day outcomesCoronary artery bypassHeart failure careElderly Medicare patientsElderly Medicare beneficiariesArtery bypassElderly patientsTransplant candidatesMedicare beneficiariesHospitalPatients
2003
Patient characteristics associated with underuse of angiotensin-converting enyzme inhibitors among elderly medicare beneficiaries hospitalized for heart failure
Rathore S, Masoudi F, Wang Y, Foody J, Havranek E, Krumholz H. Patient characteristics associated with underuse of angiotensin-converting enyzme inhibitors among elderly medicare beneficiaries hospitalized for heart failure. Journal Of Cardiac Failure 2003, 9: s85. DOI: 10.1016/s1071-9164(03)00153-2.Peer-Reviewed Original ResearchElderly Medicare beneficiariesPatient characteristicsHeart failureMedicare beneficiariesAngiotensinUnderuse
2002
Nonsteroidal antiinflammatory drugs after acute myocardial infarction
Ko D, Wang Y, Berger AK, Radford MJ, Krumholz HM. Nonsteroidal antiinflammatory drugs after acute myocardial infarction. American Heart Journal 2002, 143: 475-481. PMID: 11868054, DOI: 10.1067/mhj.2002.121270.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionNonsteroidal antiinflammatory drugsNSAID therapyMyocardial infarctionAddition of aspirinMortality rateAspirin therapyElderly patientsAntiinflammatory drugsMedicare beneficiariesUse of NSAIDsRetrospective medical record reviewAdditional survival benefitMedical record reviewCooperative Cardiovascular ProjectElderly Medicare beneficiariesHospital dischargeOlder patientsSurvival benefitRecord reviewClinical informationInfarctionAspirinPatientsMedications
1999
Do “America's Best Hospitals” Perform Better for Acute Myocardial Infarction?
Chen J, Radford M, Wang Y, Marciniak T, Krumholz H. Do “America's Best Hospitals” Perform Better for Acute Myocardial Infarction? New England Journal Of Medicine 1999, 340: 286-292. PMID: 9920954, DOI: 10.1056/nejm199901283400407.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAgedAngioplasty, Balloon, CoronaryAspirinFemaleHealth Care SurveysHospitalsHumansLogistic ModelsMaleMedicareMultivariate AnalysisMyocardial InfarctionOutcome and Process Assessment, Health CareQuality of Health CareSeverity of Illness IndexThrombolytic TherapyUnited StatesConceptsAcute myocardial infarctionShort-term mortalityMyocardial infarctionAmerica's Best HospitalsBest HospitalsSurvival advantageLower short-term mortalityBeta-blocker therapyRates of therapyHigh rateOutcomes of patientsUse of aspirinCooperative Cardiovascular ProjectElderly Medicare beneficiariesType of hospitalQuality of hospitalsReperfusion therapyElderly patientsRate of useBypass surgeryCardiac catheterizationCoronary angioplastyMedicare beneficiariesInfarctionAspirin
1995
Aspirin in the treatment of acute myocardial infarction in elderly Medicare beneficiaries. Patterns of use and outcomes.
Krumholz H, Radford M, Ellerbeck E, Hennen J, Meehan T, Petrillo M, Wang Y, Kresowik T, Jencks S. Aspirin in the treatment of acute myocardial infarction in elderly Medicare beneficiaries. Patterns of use and outcomes. Circulation 1995, 92: 2841-7. PMID: 7586250, DOI: 10.1161/01.cir.92.10.2841.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionUse of aspirinDays of hospitalizationElderly patientsMyocardial infarctionMedicare beneficiariesHospital medical recordsElderly Medicare beneficiariesHigh-risk characteristicsPopulation-based sampleDelivery of careQuality of careAspirin therapyMore comorbiditiesAspirin useChest painAbsolute contraindicationHeart failureThrombolytic therapyPotential confoundersMedical recordsSafe treatmentEffective therapyHigh riskLower oddsReadmission rates, 30 days and 365 days postdischarge, among the 20 most frequent DRG groups, Medicare inpatients age 65 or older in Connecticut hospitals, fiscal years 1991, 1992, and 1993.
Hennen J, Krumholz HM, Radford MJ, Meehan TP. Readmission rates, 30 days and 365 days postdischarge, among the 20 most frequent DRG groups, Medicare inpatients age 65 or older in Connecticut hospitals, fiscal years 1991, 1992, and 1993. Connecticut Medicine 1995, 59: 263-70. PMID: 7600797.Peer-Reviewed Original ResearchConceptsCrude readmission ratesReadmission ratesDRG categoriesConnecticut acute care hospitalsAge 65Three-year study periodStudy periodElderly Medicare beneficiariesAcute care hospitalsInpatients age 65Days postdischargeFiscal year 1991Inpatient admissionsInpatients ageConnecticut hospitalsAge 75Medicare beneficiariesAge groupsDRG groupsSignificant decreaseHospitalCorresponding ratesAgeFY 1993YearsMortality experience, 30-days and 365-days after admission, for the 20 most frequent DRG groups among Medicare inpatients aged 65 or older in Connecticut hospitals, fiscal years 1991, 1992, and 1993.
Hennen J, Krumholz HM, Radford MJ. Mortality experience, 30-days and 365-days after admission, for the 20 most frequent DRG groups among Medicare inpatients aged 65 or older in Connecticut hospitals, fiscal years 1991, 1992, and 1993. Connecticut Medicine 1995, 59: 137-42. PMID: 7729135.Peer-Reviewed Original ResearchConceptsCrude mortality rateMortality rateDRG categoriesFiscal year 1991Medicare inpatientConnecticut acute care hospitalsThree-year study periodStudy periodElderly Medicare beneficiariesAcute care hospitalsInpatient admissionsConnecticut hospitalsAge 75Medicare beneficiariesFiscal year 1993Age 65Age groupsMortality experienceDRG groupsYears 1991AdmissionInpatientsHospitalMortality differentialsThree-year periodTwenty most frequent DRG groups among Medicare inpatients age 65 or older in Connecticut hospitals, fiscal years 1991, 1992, and 1993.
Hennen J, Krumholz HM, Radford MJ. Twenty most frequent DRG groups among Medicare inpatients age 65 or older in Connecticut hospitals, fiscal years 1991, 1992, and 1993. Connecticut Medicine 1995, 59: 11-5. PMID: 7859443.Peer-Reviewed Original ResearchConceptsDRG categoriesConnecticut acute care hospitalsElderly Medicare beneficiariesElderly Medicare patientsAge group 65Acute care hospitalsInpatients age 65Care hospitalFiscal year 1991Inpatient admissionsInpatients ageConnecticut hospitalsGroup 65Medicare patientsAge subgroupsMedicare beneficiariesThree-year study periodAge 65Study periodDRG groupsNumber of dischargesMedicare dischargesHospitalYear periodYears