2017
Assessing the reliability of self-reported weight for the management of heart failure: application of fraud detection methods to a randomised trial of telemonitoring
Steventon A, Chaudhry SI, Lin Z, Mattera JA, Krumholz HM. Assessing the reliability of self-reported weight for the management of heart failure: application of fraud detection methods to a randomised trial of telemonitoring. BMC Medical Informatics And Decision Making 2017, 17: 43. PMID: 28420352, PMCID: PMC5395848, DOI: 10.1186/s12911-017-0426-4.Peer-Reviewed Original ResearchConceptsEnd-digit preferenceHeart failureHeart Failure Outcomes trialEffective preventive careCharacteristics of patientsSelf-reported weightHealth care professionalsSix-month trial periodIntervention patientsMore medicationsAccuracy of reportingOutcome trialsTrial enrollmentPreventive careClinical managementUnnecessary treatmentDesign of initiativesCare professionalsPatientsRegistration numberAlert fatigueElectronic medical dataTrial periodTrialsNumber of days
2013
Regional Density of Cardiologists and Rates of Mortality for Acute Myocardial Infarction and Heart Failure
Kulkarni VT, Ross JS, Wang Y, Nallamothu BK, Spertus JA, Normand SL, Masoudi FA, Krumholz HM. Regional Density of Cardiologists and Rates of Mortality for Acute Myocardial Infarction and Heart Failure. Circulation Cardiovascular Quality And Outcomes 2013, 6: 352-359. PMID: 23680965, PMCID: PMC5323047, DOI: 10.1161/circoutcomes.113.000214.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCardiologyCohort StudiesFemaleHealth Services AccessibilityHealth Services Needs and DemandHealthcare DisparitiesHeart FailureHospitalizationHumansLinear ModelsLogistic ModelsMaleMedicareMyocardial InfarctionOdds RatioPhysiciansPneumoniaPrognosisResidence CharacteristicsRisk AssessmentRisk FactorsTime FactorsUnited StatesWorkforceConceptsAcute myocardial infarctionHeart failureHospital referral regionsMortality riskLowest quintileMyocardial infarctionReferral regionsMedicare administrative claims dataCharacteristics of patientsRisk of deathAdministrative claims dataHierarchical logistic regression modelsLogistic regression modelsRate of mortalityRegional densityHighest quintileNumber of cardiologistsWorse outcomesClaims dataPatientsPneumoniaCardiologistsHospitalizationAdmissionQuintile
2011
Improvements in Door-to-Balloon Time in the United States, 2005 to 2010
Krumholz HM, Herrin J, Miller LE, Drye EE, Ling SM, Han LF, Rapp MT, Bradley EH, Nallamothu BK, Nsa W, Bratzler DW, Curtis JP. Improvements in Door-to-Balloon Time in the United States, 2005 to 2010. Circulation 2011, 124: 1038-1045. PMID: 21859971, PMCID: PMC3598634, DOI: 10.1161/circulationaha.111.044107.Peer-Reviewed Original ResearchConceptsPrimary percutaneous coronary interventionPercutaneous coronary interventionBalloon timeCoronary interventionMedian timeST-segment elevation myocardial infarctionHigher median timeCharacteristics of patientsPercentage of patientsTimeliness of treatmentYears of ageRegistry studyMyocardial infarctionInpatient measuresPatientsHospital groupMedicaid ServicesCalendar yearInterventionMinutesMedianGroupYearsPercentageInfarction
2006
Delay in the Diagnosis of Acute Myocardial Infarction: Effect on Quality of Care and Its Assessment
Graff LG, Wang Y, Borkowski B, Tuozzo K, Foody JM, Krumholz HM, Radford MJ. Delay in the Diagnosis of Acute Myocardial Infarction: Effect on Quality of Care and Its Assessment. Academic Emergency Medicine 2006, 13: 931-938. PMID: 16894002, DOI: 10.1197/j.aem.2006.04.016.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAge DistributionAgedAged, 80 and overAngina, UnstableAspirinCohort StudiesConnecticutEvidence-Based MedicineFemaleFibrinolytic AgentsHumansMaleMyocardial InfarctionPatient AdmissionQuality Assurance, Health CareQuality of Health CareRetrospective StudiesTime FactorsConceptsAcute myocardial infarctionAdmission diagnosisBeta blockersQuality of careMyocardial infarctionDiagnosis of AMICharacteristics of patientsPercutaneous coronary interventionPrincipal discharge diagnosisEvidence-based therapiesRate of administrationCoronary interventionCardiac catheterizationDischarge diagnosisPrincipal diagnosisFrequency of delaysDischarge statusPatient careAdmissionAMI diagnosisPatientsDiagnosisMedicare casesCareInfarction
2002
Representation of the elderly, women, and minorities in heart failure clinical trials.
Heiat A, Gross CP, Krumholz HM. Representation of the elderly, women, and minorities in heart failure clinical trials. JAMA Internal Medicine 2002, 162: 1682-8. PMID: 12153370, DOI: 10.1001/archinte.162.15.1682.Peer-Reviewed Original ResearchConceptsClinical trialsHF RCTsHeart failure clinical trialsCharacteristics of patientsSystolic ejection fractionFuture clinical trialsInvasive diagnostic testsCharacteristics of participantsType of interventionChronic HFHF trialsEjection fractionHF populationExclusion criteriaGeneralizability of evidenceRCTsAdditional trialsPatientsDiagnostic testsTrialsOriginal reportMore participantsPrincipal investigatorWomenPublication year
2001
Do Existing Databases Answer Clinical Questions about Geriatric Cardiovascular Disease and Stroke?
Cheitlin MD, Gerstenblith G, Hazzard WR, Pasternak R, Fried LP, Rich MW, Krumholz HM, Peterson E, Reves JG, McKay C, Saksena S, Shen WK, Akhtar M, Brass LM, Biller J. Do Existing Databases Answer Clinical Questions about Geriatric Cardiovascular Disease and Stroke? The American Journal Of Geriatric Cardiology 2001, 10: 207-223. PMID: 11455241, DOI: 10.1111/j.1076-7460.2003.00696.x.Peer-Reviewed Original ResearchConceptsCardiovascular diseaseYounger patientsChronic coronary artery diseaseExtrapolation of safetyRole of revascularizationChronic heart failurePatients 75 yearsRisk factor modificationCharacteristics of patientsCoronary artery diseaseAcute myocardial infarctionYears of ageCollaborative outcomes researchPrincipal investigatorGeriatric cardiologyValve surgeryArtery diseaseHeart failureCarotid endarterectomyFactor modificationMyocardial infarctionEfficacy dataCardiovascular conditionsClinical questionsAvailable safety