2020
Relationship of Age With the Hemodynamic Parameters in Individuals With Elevated Blood Pressure
Mahajan S, Gu J, Caraballo C, Lu Y, Spatz ES, Zhao H, Zhang M, Sun N, Zheng X, Lu H, Yuan H, J. Z, Krumholz HM. Relationship of Age With the Hemodynamic Parameters in Individuals With Elevated Blood Pressure. Journal Of The American Geriatrics Society 2020, 68: 1520-1528. PMID: 32212398, DOI: 10.1111/jgs.16411.Peer-Reviewed Original ResearchConceptsElevated blood pressureBlood pressureCardiac indexHemodynamic profileHemodynamic parametersHealth checkup centerFinal study populationPathophysiology of hypertensionSelection of therapyCross-sectional studyMin/Relationship of ageDifferent age groupsHemodynamic assessmentMean ageStudy populationMAIN OUTCOMEAge strataAge groupsLarger studyImpedance cardiographyAgeSVRIWomenMen
2014
Age-specific gender differences in early mortality following ST-segment elevation myocardial infarction in China
Zheng X, Dreyer RP, Hu S, Spatz ES, Masoudi FA, Spertus JA, Nasir K, Li X, Li J, Wang S, Krumholz HM, Jiang L. Age-specific gender differences in early mortality following ST-segment elevation myocardial infarction in China. Heart 2014, 101: 349. PMID: 25510395, PMCID: PMC4453015, DOI: 10.1136/heartjnl-2014-306456.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAge FactorsAgedAged, 80 and overChinaDrug UtilizationFemaleHospital MortalityHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMaleMiddle AgedMyocardial InfarctionMyocardial RevascularizationPercutaneous Coronary InterventionPlatelet Aggregation InhibitorsRetrospective StudiesRural PopulationSex FactorsUrban PopulationConceptsST-segment elevation myocardial infarctionElevation myocardial infarctionGender-age interactionHospital mortalityEarly mortalityMyocardial infarctionChina PEACE-Retrospective AMI StudyHospital mortality rateYears of ageAge-specific gender differencesPatient characteristicsHospital characteristicsMultivariable modelMortality rateGender differencesChinese populationMortalityYounger groupChinese hospitalsWomenAMI studyMenInfarctionAgeRepresentative sampleReadmission Rates and Long-Term Hospital Costs Among Survivors of an In-Hospital Cardiac Arrest
Chan PS, Nallamothu BK, Krumholz HM, Curtis LH, Li Y, Hammill BG, Spertus JA. Readmission Rates and Long-Term Hospital Costs Among Survivors of an In-Hospital Cardiac Arrest. Circulation Cardiovascular Quality And Outcomes 2014, 7: 889-895. PMID: 25351479, PMCID: PMC4241155, DOI: 10.1161/circoutcomes.114.000925.Peer-Reviewed Original ResearchConceptsHospital cardiac arrestCardiac arrestInpatient costsMean inpatient costsLarge national registryInpatient resource useNeurological statusReadmission patternsHospital dispositionPatient demographicsReadmission ratesMean ageInpatient useNational registryYounger ageReadmissionArrestAgeYearsDaysPatientsRegistryResource useSurvivors
2007
Failure to Rescue
Horwitz LI, Cuny JF, Cerese J, Krumholz HM. Failure to Rescue. Medical Care 2007, 45: 283-287. PMID: 17496710, DOI: 10.1097/01.mlr.0000250226.33094.d4.Peer-Reviewed Original ResearchConceptsChart reviewQuality Patient Safety IndicatorsRetrospective chart reviewPatient safety indicatorsRate of deathAdministrative dataHospital complicationsComplication typePatient agePatient characteristicsPrimary outcomeNonsurgical casesInsurance statusComplicationsHealthcare ResearchPatientsMortalityConsortium institutionsAgeSafety indicatorsFailureReviewHospitalizationAdmissionCases
2003
Age does not limit quality of life improvement in cardiac valve surgery
Sedrakyan A, Vaccarino V, Paltiel AD, Elefteriades JA, Mattera JA, Roumanis SA, Lin Z, Krumholz HM. Age does not limit quality of life improvement in cardiac valve surgery. Journal Of The American College Of Cardiology 2003, 42: 1208-1214. PMID: 14522482, DOI: 10.1016/s0735-1097(03)00949-5.Peer-Reviewed Original ResearchConceptsMental component summaryQuality of lifeCardiac valve surgeryPhysical component summaryValve surgeryAssociation of ageValve proceduresComponent summarySF-36PCS scoresMedical Outcomes Trust Short FormPatients' QOLMitral valve proceduresAortic valve proceduresOlder patientsAortic patientsMCS scoresMitral patientsQOL benefitsHealth SurveyPatientsSurgeryStatistical significanceAgeMultiple regression analysis
2001
Cardiopatía isquémica en el anciano
Krumholz H. Cardiopatía isquémica en el anciano. Revista Española De Cardiología 2001, 54: 819-826. PMID: 11446955, DOI: 10.1016/s0300-8932(01)76405-6.Peer-Reviewed Original ResearchConceptsOlder patientsClinical trialsClinical practiceObservational studyPrognosis of illnessOlder patient groupGroup of patientsAcute myocardial infarctionDaily clinical practiceComorbidities increasesYounger patientsHeart failureMortal complicationsPatient groupMyocardial infarctionHigh incidencePatientsMedical focusFunctional changesField of cardiologyTrialsPublic healthDevelopment of strategiesHeterogeneous populationAge
1998
Clinical correlates of in-hospital costs for acute myocardial infarction in patients 65 years of age and older
Krumholz H, Chen J, Murillo J, Cohen D, Radford M. Clinical correlates of in-hospital costs for acute myocardial infarction in patients 65 years of age and older. American Heart Journal 1998, 135: 523-531. PMID: 9506340, DOI: 10.1016/s0002-8703(98)70331-x.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionPatients 65 yearsHospital costsMyocardial infarctionAcute myocardial infarction hospitalizationsActual clinical practiceMyocardial infarction hospitalizationsClinical characteristicsAdverse outcomesClinical correlatesMedical recordsClinical practiceHospital proceduresRoom costsInfarctionStudy sampleTotal meanRelative paucityAgeLarge proportionCorrelatesHospitalizationPatientsHospitalYears
1997
Differences in physician compensation for cardiovascular services by age, sex, and race.
Krumholz HM, Fendrick AM, Williams C, Hynes WM. Differences in physician compensation for cardiovascular services by age, sex, and race. The American Journal Of Managed Care 1997, 3: 557-63. PMID: 10169524.Peer-Reviewed Original ResearchConceptsConsecutive patientsCoronary angioplastyCardiovascular servicesPercutaneous transluminal coronary angioplastyPatients 75 yearsTransluminal coronary angioplastyPercutaneous coronary angioplastyPatients 40Patients 65Patient characteristicsPatient groupInsurance statusCardiology practicePhysiciansStress testingAngioplastySignificant differencesPatientsLower ratesSimilar differencesPhysician compensationAgeSexYearsDifferences
1995
Readmission rates, 30 days and 365 days postdischarge, among the 20 most frequent DRG groups, Medicare inpatients age 65 or older in Connecticut hospitals, fiscal years 1991, 1992, and 1993.
Hennen J, Krumholz HM, Radford MJ, Meehan TP. Readmission rates, 30 days and 365 days postdischarge, among the 20 most frequent DRG groups, Medicare inpatients age 65 or older in Connecticut hospitals, fiscal years 1991, 1992, and 1993. Connecticut Medicine 1995, 59: 263-70. PMID: 7600797.Peer-Reviewed Original ResearchConceptsCrude readmission ratesReadmission ratesDRG categoriesConnecticut acute care hospitalsAge 65Three-year study periodStudy periodElderly Medicare beneficiariesAcute care hospitalsInpatients age 65Days postdischargeFiscal year 1991Inpatient admissionsInpatients ageConnecticut hospitalsAge 75Medicare beneficiariesAge groupsDRG groupsSignificant decreaseHospitalCorresponding ratesAgeFY 1993YearsSex differences in mortality after myocardial infarction. Is there evidence for an increased risk for women?
Vaccarino V, Krumholz H, Berkman L, Horwitz R. Sex differences in mortality after myocardial infarction. Is there evidence for an increased risk for women? Circulation 1995, 91: 1861-71. PMID: 7882498, DOI: 10.1161/01.cir.91.6.1861.Peer-Reviewed Original ResearchConceptsMyocardial infarctionMortality rateIncreased early mortalitySex differencesUnadjusted mortality ratesHigh mortality rateEnglish-language literatureEarly phaseImproved survivalPatient seriesEarly mortalityFemale sexRisk factorsOutcome eventsCrude rateMEDLINE searchInfarctionSurvival rateOlder ageMortalityWomenAgeMenNumber of studiesLower survival