2024
Effects of gestational hypothyroidism on mouse brain development: Gabaergic systems and oxidative stress
da Cunha Menezes E, de Abreu F, Davis J, Maurer S, Roshko V, Richardson A, Dowell J, Cassella S, Stevens H. Effects of gestational hypothyroidism on mouse brain development: Gabaergic systems and oxidative stress. Developmental Biology 2024, 515: 112-120. PMID: 39048051, PMCID: PMC11330572, DOI: 10.1016/j.ydbio.2024.07.010.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrainCell MovementFemaleGABAergic NeuronsGene Expression Regulation, DevelopmentalGlutamate DecarboxylaseGlutathione PeroxidaseGlutathione Peroxidase GPX1HypothyroidismMaleMethimazoleMiceNF-E2-Related Factor 2Oxidative StressPlacentaPregnancyPrenatal Exposure Delayed EffectsThyroid HormonesConceptsGestational hypothyroidismGABAergic system developmentMaternal thyroid hormone supplyThyroid hormone supplyCortical GABAergic interneuronsMaternal thyroid hormonesGene expressionCD-1 miceCentral nervous system developmentEmbryonic day 9Central nervous systemIntrauterine restrictionGABAergic interneuronsGABAergic systemGPx1 gene expressionBrain gene expressionMouse brain developmentCD-1HypothyroidismEmbryonic dayNervous system developmentThyroid hormonesRisk factorsNeural system developmentHormonal imbalance
2017
Cross‐tissue telomere length measurement to determine auxiliary marker of brain telomere length in neurosurgery patients
Lussier S, Braun P, Potash J, Shinozaki G, Stevens H. Cross‐tissue telomere length measurement to determine auxiliary marker of brain telomere length in neurosurgery patients. The FASEB Journal 2017, 31 DOI: 10.1096/fasebj.31.1_supplement.lb60.Peer-Reviewed Original ResearchCentral nervous systemBlood telomere lengthCentral nervous system measuresNeurosurgery patientsTelomere lengthTelomere length measurementAcute time courseExposure to glucocorticoidsCoronary artery diseasePost-surgery samplesRisk of strokeResection surgeryArtery diseaseSynthetic glucocorticoidSamples of bloodLength measurementsExposure to stressRemoved tissueHeart diseaseHuman studiesAverage agePatientsPeripheral tissuesSurgeryPeripheral measures