2023
Mapping Lesion-Related Epilepsy to a Human Brain Network
Schaper F, Nordberg J, Cohen A, Lin C, Hsu J, Horn A, Ferguson M, Siddiqi S, Drew W, Soussand L, Winkler A, Simó M, Bruna J, Rheims S, Guenot M, Bucci M, Nummenmaa L, Staals J, Colon A, Ackermans L, Bubrick E, Peters J, Wu O, Rost N, Grafman J, Blumenfeld H, Temel Y, Rouhl R, Joutsa J, Fox M. Mapping Lesion-Related Epilepsy to a Human Brain Network. JAMA Neurology 2023, 80: 891-902. PMID: 37399040, PMCID: PMC10318550, DOI: 10.1001/jamaneurol.2023.1988.Peer-Reviewed Original ResearchConceptsRisk of epilepsyLesion locationBrain regionsPoststroke epilepsyControl patientsSeizure controlBrain lesionsIndependent cohortBrain networksLesion typeBrain stimulation sitesLesion network mappingLesion-related epilepsyImproved seizure controlDrug-resistant epilepsyCase-control studyBrain stimulation therapyHuman brain networksSpecific brain regionsDifferent lesion typesSpecific brain networksBasal gangliaVascular territoriesStimulation therapyMAIN OUTCOME
2014
Chapter 33 Future Trends in Neuronal Networks—Selective and Combined Targeting of Network Hubs
Faingold C, Blumenfeld H. Chapter 33 Future Trends in Neuronal Networks—Selective and Combined Targeting of Network Hubs. 2014, 467-485. DOI: 10.1016/b978-0-12-415804-7.00033-2.Peer-Reviewed Original ResearchCNS disordersDrug therapyCentral nervous systemSpecific CNS disordersStimulation paradigmFuture therapiesAbnormal neuronal firing patternsEffective stimulation paradigmsSpecific pathophysiological mechanismsSpecific brain sitesAppropriate animal modelsSelective drug therapyNew potential therapiesPotential therapeutic targetPotential drug therapiesNeuronal firing patternsTypes of drugsChronic painNeuronal responsivenessPathophysiological mechanismsCurrent therapiesTherapeutic dosesCholinergic stimulationMajor depressionStimulation therapy
2009
Brain imaging and electroconvulsive therapy
Peng K, Blumenfeld H. Brain imaging and electroconvulsive therapy. 2009, 94-108. DOI: 10.1017/cbo9780511576393.006.Peer-Reviewed Original ResearchElectroconvulsive therapyClinical practiceBrain stimulation therapyMedication therapyTreatment modalitiesAntipsychotic drugsStimulation therapyNeuromodulation therapiesPsychiatric treatmentTherapyBrain imagingBody healthClinical proceduresDrugsModalitiesElectroconvulsiveRecent refinementsSeizuresCliniciansBrain