2019
Dietary quality and the colonic mucosa–associated gut microbiome in humans
Liu Y, Ajami N, El-Serag H, Hair C, Graham D, White D, Chen L, Wang Z, Plew S, Kramer J, Cole R, Hernaez R, Hou J, Husain N, Jarbrink-Sehgal M, Kanwal F, Ketwaroo G, Natarajan Y, Shah R, Velez M, Mallepally N, Petrosino J, Jiao L. Dietary quality and the colonic mucosa–associated gut microbiome in humans. American Journal Of Clinical Nutrition 2019, 110: 701-712. PMID: 31291462, PMCID: PMC6736447, DOI: 10.1093/ajcn/nqz139.Peer-Reviewed Original ResearchConceptsTotal HEIColonic mucosaHigher BacteroidesDietary qualityGut microbiomeCross-sectional observational studyLower scoresColonic mucosal biopsiesHealthy Eating IndexDifferent colon segmentsMucosal biopsiesMultivariable analysisObservational studyColon segmentsDietary consumptionHealthy individualsMultivariate analysisFree participantsMucosaNormal individualsFusobacteriumWhole grainsTaxonomic relative abundancesScoresSoy beverageDietary Nutrients Involved in One-Carbon Metabolism and Colonic Mucosa-Associated Gut Microbiome in Individuals with an Endoscopically Normal Colon
Gurwara S, Ajami N, Jang A, Hessel F, Chen L, Plew S, Wang Z, Graham D, Hair C, White D, Kramer J, Kourkoumpetis T, Hoffman K, Cole R, Hou J, Husain N, Jarbrink-Sehgal M, Hernaez R, Kanwal F, Ketwaroo G, Shah R, Velez M, Natarajan Y, El-Serag H, Petrosino J, Jiao L. Dietary Nutrients Involved in One-Carbon Metabolism and Colonic Mucosa-Associated Gut Microbiome in Individuals with an Endoscopically Normal Colon. Nutrients 2019, 11: 613. PMID: 30871224, PMCID: PMC6470629, DOI: 10.3390/nu11030613.Peer-Reviewed Original ResearchMeSH KeywordsAgedBacteriaColonCross-Sectional StudiesDietFood AnalysisGastrointestinal MicrobiomeHumansIntestinal MucosaMaleMiddle AgedProspective StudiesConceptsB vitaminsDietary consumptionGut microbiotaMucosa-associated gut microbiotaConsumption of folateFood frequency questionnaireHigh consumptionFrequency questionnaireColonic biopsiesNormal colonGut microbiomeColonic bacteriaOne-carbon metabolismDaily consumptionOperational taxonomic unit classificationStatistical significanceDietary nutrientsTaxonomic relative abundancesVitaminFolateMicrobiota
2016
Risk Profiles for Barrett’s Esophagus Differ between New and Prevalent, and Long- and Short-Segment Cases
Tan M, Murrey-Ittmann J, Nguyen T, Ketwaroo G, El-Serag H, Thrift A. Risk Profiles for Barrett’s Esophagus Differ between New and Prevalent, and Long- and Short-Segment Cases. PLOS ONE 2016, 11: e0169250. PMID: 28036381, PMCID: PMC5201279, DOI: 10.1371/journal.pone.0169250.Peer-Reviewed Original ResearchConceptsSpecialized intestinal metaplasiaShort-segment BELong-segment BEPrimary care controlsH. pylori infectionRisk factorsGERD symptomsElective esophagogastroduodenoscopyEndoscopy controlsCare controlPylori infectionCase definitionBE casesControl groupGastroesophageal reflux disease symptomsMultivariate logistic regression modelFrequent GERD symptomsPrimary care clinicsCross-sectional studyVeterans Affairs centersLogistic regression modelsEligible patientsH2RA useMedication useCare clinics