2013
Tissue-specific direct targets of Caenorhabditis elegans Rb/E2F dictate distinct somatic and germline programs
Kudron M, Niu W, Lu Z, Wang G, Gerstein M, Snyder M, Reinke V. Tissue-specific direct targets of Caenorhabditis elegans Rb/E2F dictate distinct somatic and germline programs. Genome Biology 2013, 14: r5. PMID: 23347407, PMCID: PMC4053757, DOI: 10.1186/gb-2013-14-1-r5.Peer-Reviewed Original ResearchConceptsRb/E2FLin-35Target genesGenome-wide binding profilesGene expressionTissue-specific gene regulationLin-35 mutantsDistinct cell fatesSmall RNA pathwaysEffector target genesDirect target geneBinding profileGermline programHPL-2Chromatin associationH3K36 methylationRNA pathwaysCSR-1Germline transformationC. elegansGene regulationCell fateE2FDirect targetMultiple tissues
2011
A Comprehensive Analysis of Gene Expression Changes Provoked by Bacterial and Fungal Infection in C. elegans
Engelmann I, Griffon A, Tichit L, Montañana-Sanchis F, Wang G, Reinke V, Waterston RH, Hillier LW, Ewbank JJ. A Comprehensive Analysis of Gene Expression Changes Provoked by Bacterial and Fungal Infection in C. elegans. PLOS ONE 2011, 6: e19055. PMID: 21602919, PMCID: PMC3094335, DOI: 10.1371/journal.pone.0019055.Peer-Reviewed Original ResearchConceptsC. elegansGenome-wide transcriptional changesFuture functional dissectionGene expression changesInnate immune signalingFunctional dissectionTranscriptional responseAnnotation analysisTranscriptional changesD. coniosporaRNA sequencingFungal pathogensCertain genesExpression changesImmune signalingSmall proteinsStress responseElegansGenesDistinct pathogensBacterial pathogensPathogensPhysiological imbalanceFungal infectionsHost response