1999
The effect of ursodeoxycholic acid on the florid duct lesion of primary biliary cirrhosis
Combes B, Markin R, Wheeler D, Rubin R, West A, Mills A, Eigenbrodt E, Maddrey W, Munoz S, Garcia‐Tsao G, Bonner G, Boyer J, Luketic V, Shiffman M, Peters M, White H, Zetterman R, Carithers R. The effect of ursodeoxycholic acid on the florid duct lesion of primary biliary cirrhosis. Hepatology 1999, 30: 602-605. PMID: 10462363, PMCID: PMC3935822, DOI: 10.1002/hep.510300315.Peer-Reviewed Original ResearchConceptsFlorid duct lesionsPrimary biliary cirrhosisBile duct destructionDuct lesionsUrsodeoxycholic acidDuct destructionBiliary cirrhosisPlacebo-controlled trialNeedle biopsy specimensUDCA patientsAdvanced diseasePlacebo medicationEarly diseaseBiopsy specimensPatientsLesionsBeneficial effectsPathology literaturePrevalenceCirrhosisPlaceboMedicationsDiseaseYearsHepatopathologistBiliary bile acids in primary biliary cirrhosis: Effect of ursodeoxycholic acid
Combes B, Carithers R, Maddrey W, Munoz S, Garcia‐Tsao G, Bonner G, Boyer J, Luketic V, Shiffman M, Peters M, White H, Zetterman R, Risser R, Rossi S, Hofmann A. Biliary bile acids in primary biliary cirrhosis: Effect of ursodeoxycholic acid. Hepatology 1999, 29: 1649-1654. PMID: 10347103, PMCID: PMC4004074, DOI: 10.1002/hep.510290618.Peer-Reviewed Original ResearchMeSH KeywordsBileBile Acids and SaltsChenodeoxycholic AcidCholic AcidChromatography, GasChromatography, High Pressure LiquidDeoxycholic AcidDouble-Blind MethodDrug Administration ScheduleFemaleHumansLithocholic AcidLiver Cirrhosis, BiliaryMaleMiddle AgedPlacebosRegression AnalysisReproducibility of ResultsTime FactorsUrsodeoxycholic AcidConceptsPrimary biliary cirrhosisBile acid compositionUrsodeoxycholic acidBile acidsBiliary cirrhosisSeverity of PBCSingle bedtime dosePlacebo-controlled trialBiliary bile acidsEndogenous bile acidsMajor bile acidsBedtime dosePlacebo medicationDuodenal bileHigh-pressure liquid chromatography methodPatientsNormal personsBileSignificant decreaseCirrhosisAcid compositionCDCATaurineLiquid chromatography methodYears
1990
Role of the distal splenorenal shunt in management of variceal bleeding in Latin America
Orozco H, Mercado M, Takahashi T, García-Tsao G, Guevara L, Ortíz J, Hernández-Cendejas A, Tielve M. Role of the distal splenorenal shunt in management of variceal bleeding in Latin America. The American Journal Of Surgery 1990, 160: 86-89. PMID: 2368881, DOI: 10.1016/s0002-9610(05)80874-8.Peer-Reviewed Original ResearchConceptsSelective shuntWarren shuntPortal hypertensionSplenorenal shuntDistal splenorenal shuntNormal liver functionTreatment of choiceSplenocaval shuntOperative mortalityVariceal bleedingShunt thrombosisVenous diameterLiver functionShuntChild classHypertensionThrombosisPatientsTreatmentYearsRegular basisLatin American countriesBleedingSchistosomiasisMortalitySelective portal-systemic shunts for bleeding portal hypertension.
Orozco H, Mercado M, Takahashi T, García-Tsao G, Guevara L, Hernandez-Ortiz J, Tielve M. Selective portal-systemic shunts for bleeding portal hypertension. Revista De Investigación Clínica 1990, 42 Suppl: 165-9. PMID: 19256158.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedChildEsophageal and Gastric VaricesFemaleGastrointestinal HemorrhageHumansHypersplenismHypertension, PortalKaplan-Meier EstimateLiver CirrhosisMaleMiddle AgedPatient SelectionPortal VeinPortasystemic Shunt, SurgicalPostoperative ComplicationsRecurrenceRetrospective StudiesSeverity of Illness IndexThrombosisYoung AdultConceptsSelective shuntPortal hypertensionOperative mortalityChild A groupChild A patientsGlobal operative mortalityPortal-systemic shuntsGood liver functionTreatment of choiceElective fashionSplenocaval shuntWarren shuntPostoperative periodA patientsShunt thrombosisLiver functionHypertensionShuntPatientsA groupThrombosisMortalityYear periodTreatmentYearsSurgical treatment of hemorrhage of esophageal varices secondary to thrombosis of the portal vein.
Orozco-Zepeda H, Takahashi T, Angel Mercado M, García-Tsao G, Hernández-Ortiz J. Surgical treatment of hemorrhage of esophageal varices secondary to thrombosis of the portal vein. Revista De Gastroenterología De México 1990, 55: 215-9. PMID: 2091189.Peer-Reviewed Original ResearchConceptsHemorrhagic portal hypertensionSugiura procedurePortal hypertensionAssociated liver diseasePortal vein thrombosisProtein C deficiencyActuarial survivalOperative deathsSurgical treatmentVein thrombosisEsophageal varicesLiver diseaseMean ageSurgical stagePortal veinC deficiencyPatientsHypertensionThrombosisEPVTVaricesHemorrhageCasesYearsDisease