2016
Role of mitochondrial uncoupling protein-2 (UCP2) in higher brain functions, neuronal plasticity and network oscillation
Hermes G, Nagy D, Waterson M, Zsarnovszky A, Varela L, Hajos M, Horvath TL. Role of mitochondrial uncoupling protein-2 (UCP2) in higher brain functions, neuronal plasticity and network oscillation. Molecular Metabolism 2016, 5: 415-421. PMID: 27257601, PMCID: PMC4877662, DOI: 10.1016/j.molmet.2016.04.002.Peer-Reviewed Original ResearchMouse modelSynaptic plasticityMental illnessUCP2 knockout miceNMDA receptor blockadeHigher brain regionsKO mouse modelMajor psychiatric illnessProtein 2 expressionHigher brain functionsReceptor blockadePsychiatric illnessNeuronal plasticityKnockout miceNeural transmissionCellular resilienceCortical activityBrain regionsProfound disorderBrain functionMitochondrial impairmentIllnessNetwork oscillationsMitochondrial functionProtein 2
2015
Neural plasticity in hypocretin neurons: the basis of hypocretinergic regulation of physiological and behavioral functions in animals
Gao XB, Hermes G. Neural plasticity in hypocretin neurons: the basis of hypocretinergic regulation of physiological and behavioral functions in animals. Frontiers In Systems Neuroscience 2015, 9: 142. PMID: 26539086, PMCID: PMC4612503, DOI: 10.3389/fnsys.2015.00142.Peer-Reviewed Original ResearchHypocretin systemNormal physiological functionPhysiological functionsNeural plasticityHypocretin-containing neuronsPF/LHSubstantial plastic changesCritical brain functionsPathological conditionsLong-term behavioral changesHypocretin neuronsLateral hypothalamusDaily functionNeuronal activityPlastic changesLong-term changesPlasticityMental health implicationsNeuronal systemsRecent evidenceBrain functionBehavioral functionsNeural activityHealth implicationsDaily fluctuations