2024
Quantifying White Matter Hyperintensity and Brain Volumes in Heterogeneous Clinical and Low-Field Portable MRI
Laso P, Cerri S, Sorby-Adams A, Guo J, Mateen F, Goebl P, Wu J, Liu P, Li H, Young S, Billot B, Puonti O, Sze G, Payabavash S, DeHavenon A, Sheth K, Rosen M, Kirsch J, Strisciuglio N, Wolterink J, Eshaghi A, Barkhof F, Kimberly W, Iglesias J. Quantifying White Matter Hyperintensity and Brain Volumes in Heterogeneous Clinical and Low-Field Portable MRI. 2024, 00: 1-5. DOI: 10.1109/isbi56570.2024.10635502.Peer-Reviewed Original ResearchLow-field, Portable Magnetic Resonance Imaging to Assess Hematoma Volume in Traumatic Brain Injury Patients (P10-5.008)
Zabinska J, Yadlapalli V, Mazurek M, Parasuram N, Lalwani D, Peasley E, Gilmore E, Kim J, Omay S, Sze G, Payabvash S, Sorby-Adams A, Iglesias J, Rosen M, Kimberly W, Sheth K. Low-field, Portable Magnetic Resonance Imaging to Assess Hematoma Volume in Traumatic Brain Injury Patients (P10-5.008). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000208210.Peer-Reviewed Original Research
2021
Low-Field, Portable Magnetic Resonance Imaging at the Bedside to Assess Brain Injury in Patients with Severe COVID-19 (1349)
Mazurek M, Yuen M, Cahn B, Rosen M, Gobeske K, Gilmore E, Hwang D, Kaddouh F, Kim J, Falcone G, Petersen N, Siner J, Spudich S, Sze G, Kimberly W, Sheth K. Low-Field, Portable Magnetic Resonance Imaging at the Bedside to Assess Brain Injury in Patients with Severe COVID-19 (1349). Neurology 2021, 96 DOI: 10.1212/wnl.96.15_supplement.1349.Peer-Reviewed Original Research
2020
Deployment of Portable, Bedside, Low-field Magnetic Resonance Imaging for Evaluation of Stroke Patients (272)
Cahn B, Shah J, Dyvorne H, O’Halloran R, Poole M, Yuen M, Mazurek M, Ward A, Payabvash S, Beekman R, Brown S, Falcone G, Gobeske K, Petersen N, Jasne A, Sharma R, Schindler J, Sansing L, Gilmore E, Wira C, Matouk C, Sze G, Rosen M, Kimberly W, Sheth K. Deployment of Portable, Bedside, Low-field Magnetic Resonance Imaging for Evaluation of Stroke Patients (272). Neurology 2020, 94 DOI: 10.1212/wnl.94.15_supplement.272.Peer-Reviewed Original Research
2017
Apparent Diffusion Coefficient Value Changes and Clinical Correlation in 90 Cases of Cytomegalovirus-Infected Fetuses with Unremarkable Fetal MRI Results
Kotovich D, Guedalia JSB, Hoffmann C, Sze G, Eisenkraft A, Yaniv G. Apparent Diffusion Coefficient Value Changes and Clinical Correlation in 90 Cases of Cytomegalovirus-Infected Fetuses with Unremarkable Fetal MRI Results. American Journal Of Neuroradiology 2017, 38: 1443-1448. PMID: 28522662, PMCID: PMC7959907, DOI: 10.3174/ajnr.a5222.Peer-Reviewed Original ResearchConceptsCytomegalovirus-infected fetusesFetal MRVABS-II scoresADC valuesCytomegalovirus infectionFetal brainApparent diffusion coefficient (ADC) value changesNeurocognitive assessmentIntrauterine cytomegalovirus infectionCase of cytomegalovirusMost brain areasFetal MR imagingVABS-IIDiffuse reductionIntrauterine infectionNeurodevelopmental impairmentClinical findingsBasal gangliaUnremarkable findingsClinical correlationBrain evaluationRetrospective analysisAge control groupTemporal lobeMRI resultsLong Term Outcomes of IV Glyburide In Patients 70 Years of Age or Under: Subgroup Analysis from the Phase II GAMES-RP Study of Patients with Large Hemispheric Infarction (S29.008)
Sheth K, Cheung K, Elm J, Hinson H, Molyneaux B, Beslow L, Sze G, Ostwaldt A, Kimberly W. Long Term Outcomes of IV Glyburide In Patients 70 Years of Age or Under: Subgroup Analysis from the Phase II GAMES-RP Study of Patients with Large Hemispheric Infarction (S29.008). Neurology 2017, 88 DOI: 10.1212/wnl.88.16_supplement.s29.008.Peer-Reviewed Original Research
2016
GAMES (Glyburide Advantage in Malignant Edema and Stroke) RP: A Phase II Study Toward Preventing Edema After Ischemia (I11.006)
Sheth K, Elm J, Hinson H, Molyneaux B, Beslow L, Sze G, Ostwaldt A, Del Zoppo G, Simard J, Jacobson S, Kimberly W. GAMES (Glyburide Advantage in Malignant Edema and Stroke) RP: A Phase II Study Toward Preventing Edema After Ischemia (I11.006). Neurology 2016, 86 DOI: 10.1212/wnl.86.16_supplement.i11.006.Peer-Reviewed Original ResearchGAMES (Glyburide Advantage in Malignant Edema and Stroke) RP Trial: Intermediate Endpoint Analysis as Proof-Of-Concept (I11.010)
Kimberly W, Elm J, Hinson H, Molyneaux B, Beslow L, Sze G, Ostwaldt A, Del Zoppo G, Simard M, Sheth K. GAMES (Glyburide Advantage in Malignant Edema and Stroke) RP Trial: Intermediate Endpoint Analysis as Proof-Of-Concept (I11.010). Neurology 2016, 86 DOI: 10.1212/wnl.86.16_supplement.i11.010.Peer-Reviewed Original ResearchGAMES (Glyburide Advantage in Malignant Edema and Stroke) RP: A Phase II Study Toward Preventing Edema After Ischemia (S7.004)
Sheth K, Elm J, Hinson H, Molyneaux B, Beslow L, Sze G, Ostwaldt A, Del Zoppo G, Simard J, Jacobson S, Kimberly W. GAMES (Glyburide Advantage in Malignant Edema and Stroke) RP: A Phase II Study Toward Preventing Edema After Ischemia (S7.004). Neurology 2016, 86 DOI: 10.1212/wnl.86.16_supplement.s7.004.Peer-Reviewed Original ResearchGAMES (Glyburide Advantage in Malignant Edema and Stroke) RP Trial: Intermediate Endpoint Analysis as Proof-Of-Concept (S7.006)
Kimberly W, Elm J, Hinson H, Molyneaux B, Beslow L, Sze G, Ostwaldt A, Del Zoppo G, Simard M, Sheth K. GAMES (Glyburide Advantage in Malignant Edema and Stroke) RP Trial: Intermediate Endpoint Analysis as Proof-Of-Concept (S7.006). Neurology 2016, 86 DOI: 10.1212/wnl.86.16_supplement.s7.006.Peer-Reviewed Original ResearchPrenatal stress alters amygdala functional connectivity in preterm neonates
Scheinost D, Kwon SH, Lacadie C, Sze G, Sinha R, Constable RT, Ment LR. Prenatal stress alters amygdala functional connectivity in preterm neonates. NeuroImage Clinical 2016, 12: 381-388. PMID: 27622134, PMCID: PMC5009231, DOI: 10.1016/j.nicl.2016.08.010.Peer-Reviewed Original ResearchConceptsPrenatal stress exposurePreterm neonatesPreterm birthPrenatal stressStress exposureTerm controlsFunctional connectivityAmygdala connectivityNeuropsychiatric disordersResting-state functional magnetic resonance imagingPrenatal stress altersEarly life stressFunctional magnetic resonance imagingMagnetic resonance imagingPeristriate cortexPrenatal exposureHigh riskMaternal stressIndependent cohortNeonatesLeft amygdalaSubcortical regionsResonance imagingAmygdalaCohort
2015
Glyburide Advantage in Malignant Edema and Stroke (GAMES-RP) Trial: Rationale and Design
Sheth KN, Elm JJ, Beslow LA, Sze GK, Kimberly WT. Glyburide Advantage in Malignant Edema and Stroke (GAMES-RP) Trial: Rationale and Design. Neurocritical Care 2015, 24: 132-139. PMID: 26268138, DOI: 10.1007/s12028-015-0189-7.Peer-Reviewed Original ResearchConceptsAdverse eventsCerebral edemaContinuous infusionHigh riskAnterior circulation ischemic strokeDiffusion-weighted image (DWI) lesionsAnterior circulation infarctionLarge territory infarctionMalignant cerebral edemaPrimary efficacy outcomeSerious adverse eventsLarge hemispheric strokeYears of ageStudy infusionEfficacy outcomesTerritory infarctionIschemic strokeNeurological deteriorationRankin ScaleSymptom onsetDecompressive craniectomyMulticenter trialBrain edemaHemispheric strokeStroke trials