2023
Characterization of childhood trauma, hippocampal mediation and Cannabis use in a large dataset of psychosis and non-psychosis individuals
Del Re E, Yassin W, Zeng V, Keedy S, Alliey-Rodriguez N, Ivleva E, Hill S, Rychagov N, McDowell J, Bishop J, Mesholam-Gately R, Merola G, Lizano P, Gershon E, Pearlson G, Sweeney J, Clementz B, Tamminga C, Keshavan M. Characterization of childhood trauma, hippocampal mediation and Cannabis use in a large dataset of psychosis and non-psychosis individuals. Schizophrenia Research 2023, 255: 102-109. PMID: 36989667, DOI: 10.1016/j.schres.2023.03.029.Peer-Reviewed Original ResearchConceptsChildhood Trauma QuestionnaireChildhood traumaPsychosis onsetBipolar disorder type 1Rich brain regionsAbuse/dependenceHigh childhood traumaSevere childhood traumaPolygenic risk scoresRisk scoreClinical interviewersSchizoaffective disorderMulticenter sampleSurvival analysisCA exposureYounger ageBrain regionsType 1Psychosis riskLower ageCeiling effectsHippocampusTrauma QuestionnaireSZ-polygenic risk scoreGenetic risk
2001
Regional cortical white matter reductions in velocardiofacial syndrome: a volumetric MRI analysis
Kates W, Burnette C, Jabs E, Rutberg J, Murphy A, Grados M, Geraghty M, Kaufmann W, Pearlson G. Regional cortical white matter reductions in velocardiofacial syndrome: a volumetric MRI analysis. Biological Psychiatry 2001, 49: 677-684. PMID: 11313035, DOI: 10.1016/s0006-3223(00)01002-7.Peer-Reviewed Original ResearchConceptsWhite matter reductionLobar brain regionsVelocardiofacial syndromeWhite matterBrain regionsVolumetric MRI analysisWhite matter anomaliesWhite matter volumeMatter reductionCerebral lobesAxonal integrityPsychiatric disordersCardiac defectsMatter volumeSyndromeBrain tissueGray matterLobar volumesCSF compartmentMRI analysisBrain developmentCraniofacial anomaliesUnaffected childrenNeuropsychiatric phenotypesCoronal images
1994
Synkinesias Are Common in Down's Syndrome
Habbak R, Warren A, Phil D, Aylward E, Jerram M, Pearlson G. Synkinesias Are Common in Down's Syndrome. The Journal Of Nervous And Mental Disease 1994, 182: 667. PMID: 7964677, DOI: 10.1097/00005053-199411000-00012.Peer-Reviewed Original Research
1992
Magnetic resonance imaging in autism: measurement of the cerebellum, pons, and fourth ventricle
Piven J, Nehme E, Simon J, Barta P, Pearlson G, Folstein S. Magnetic resonance imaging in autism: measurement of the cerebellum, pons, and fourth ventricle. Biological Psychiatry 1992, 31: 491-504. PMID: 1581425, DOI: 10.1016/0006-3223(92)90260-7.Peer-Reviewed Original Research
1991
Bicaudate ratio as a measure of caudate volume on MR images.
Aylward E, Schwartz J, Machlin S, Pearlson G. Bicaudate ratio as a measure of caudate volume on MR images. American Journal Of Neuroradiology 1991, 12: 1217-22. PMID: 1763757, PMCID: PMC8331458.Peer-Reviewed Original Research
1990
Magnetic resonance imaging evidence for a defect of cerebral cortical development in autism
Piven J, Berthier M, Starkstein S, Nehme E, Pearlson G, Folstein S. Magnetic resonance imaging evidence for a defect of cerebral cortical development in autism. American Journal Of Psychiatry 1990, 147: 734-739. PMID: 2343916, DOI: 10.1176/ajp.147.6.734.Peer-Reviewed Original ResearchConceptsControl subjectsMagnetic resonance imaging (MRI) scansCerebral cortical malformationsResonance imaging scansCerebral cortical developmentAutistic subjectsMigration of neuronsMonths of gestationPathogenesis of autismCerebral cortexCortical malformationsImaging scansCortical developmentMacrogyriaPathogenesisMalformationsAbnormalitiesSubjectsScansMagnetic resonancePolymicrogyriaGestationCortexNeuronsMRI