2014
Relationships between Reward Sensitivity, Risk-Taking and Family History of Alcoholism during an Interactive Competitive fMRI Task
Yarosh HL, Hyatt CJ, Meda SA, Jiantonio-Kelly R, Potenza MN, Assaf M, D.Pearlson G. Relationships between Reward Sensitivity, Risk-Taking and Family History of Alcoholism during an Interactive Competitive fMRI Task. PLOS ONE 2014, 9: e88188. PMID: 24505424, PMCID: PMC3913753, DOI: 10.1371/journal.pone.0088188.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcoholismBasal GangliaBrain MappingFemaleHumansMagnetic Resonance ImagingMaleRewardRisk-TakingSocial BehaviorConceptsVentral striatal activationNeural correlatesImpulsivity measuresStriatal activationFHN individualsFunctional magnetic resonance imaging (fMRI) taskVentral striatum activationSelf-report measuresImpulsivity-related measuresFunctional magnetic resonanceRisk-taking scoresReward-related networksAlcohol-dependent individualsNeural underpinningsPunishment sensitivityReward responsivenessReward sensitivityFMRI taskReward processingStriatum activationSocial tasksFHP individualsMonetary rewardsAddictive behaviorsAxis I Disorders
1997
Basal ganglia volume in adults with Down syndrome
Aylward E, Li Q, Habbak R, Warren A, Pulsifer M, Barta P, Jerram M, Pearlson G. Basal ganglia volume in adults with Down syndrome. Psychiatry Research 1997, 74: 73-82. PMID: 9204510, DOI: 10.1016/s0925-4927(97)00011-5.Peer-Reviewed Original ResearchConceptsBasal ganglia volumesGanglia volumesDS subjectsBasal gangliaDown syndromeControl subjectsDementia statusNeuropsychological test performanceBrain volumeSmaller total brain volumeVolumes of caudateTotal brain volumeBasal ganglia abnormalitiesOverall brain volumeLarger putamen volumesTotal brainGlobus pallidusPutamen volumeNormal individualsGangliaTest performanceNeuropsychological testsSignificant correlationSyndromeAgeQuantification of Neuroreceptors in the Living Human Brain
Wong *, Pearlson ‡, Tune ‡, Young *, Meltzer *, Dannals *, Ravert *, Reith *, Kuhar †, Gjedde ¶. Quantification of Neuroreceptors in the Living Human Brain. Cerebrovascular And Brain Metabolism Reviews 1997, 17: 331-342. PMID: 9119906, DOI: 10.1097/00004647-199703000-00010.Peer-Reviewed Original ResearchConceptsD2-like dopamine receptorsDrug-naive schizophrenic patientsDopamine receptorsSchizophrenic patientsIllness patientsPatient groupControl subjectsReceptor densityD2 dopamine receptor densityDrug-naive schizophreniaDopamine receptor densityLiving Human BrainBipolar affective illnessD2 dopamine receptorsQuantification of NeuroreceptorsPositron emission tomographyEffect of ageBrain uptakeAffective illnessBipolar illnessNonpsychotic patientsCaudate nucleusNormal controlsNormal volunteersPatients
1996
A Quantitative MRI Study of the Basal Ganglia in Depression in HIV Seropositive Men
Davison S, Aylward E, McArthur J, Selnes O, Lyketsos C, Barta P, Pearlson G. A Quantitative MRI Study of the Basal Ganglia in Depression in HIV Seropositive Men. Journal Of LGBT Health Research 1996, 1: 29-41. PMID: 16873169, DOI: 10.1300/j128v01n03_02.Peer-Reviewed Original ResearchMeSH KeywordsBasal GangliaDepressionDepressive DisorderHIV InfectionsHumansMagnetic Resonance ImagingMaleConceptsHIV-seropositive menBasal ganglia volumesBasal ganglia atrophyBasal gangliaMagnetic resonance imagingSeropositive menGanglia volumesHIV infectionHIV-seropositive homosexual menSeropositive homosexual menHIV-seropositive patientsQuantitative MRI studyQuantitative magnetic resonance imagingSeropositive patientsSuch infectionsComparison subjectsMRI studiesHomosexual menAffective disordersDepressive symptomatologyGangliaResonance imagingInfectionSignificant differencesDepression