2024
More reliable biomarkers and more accurate prediction for mental disorders using a label-noise filtering-based dimensional prediction method
Xing Y, van Erp T, Pearlson G, Kochunov P, Calhoun V, Du Y. More reliable biomarkers and more accurate prediction for mental disorders using a label-noise filtering-based dimensional prediction method. IScience 2024, 27: 109319. PMID: 38482500, PMCID: PMC10933544, DOI: 10.1016/j.isci.2024.109319.Peer-Reviewed Original ResearchDiagnosis of mental disordersMental disordersDiagnostic labelsIntegration of neuroimagingSchizophrenia patientsNeuroimaging measuresNeuroimaging perspectiveFMRI dataStable abnormalitiesNeuroimagingDisordersHealthy controlsIndependent subjectsSchizophreniaFMRIDimensional predictionsSubjectsAccurate diagnosisClassification accuracy
2000
Sex Differences in Inferior Parietal Lobule Volume in Schizophrenia
Frederikse M, Lu A, Aylward E, Barta P, Sharma T, Pearlson G. Sex Differences in Inferior Parietal Lobule Volume in Schizophrenia. American Journal Of Psychiatry 2000, 157: 422-427. PMID: 10698819, DOI: 10.1176/appi.ajp.157.3.422.Peer-Reviewed Original ResearchConceptsGray matter volumeLobule volumesFemale subjectsSchizophrenic patientsMatter volumeMale subjectsFemale schizophrenic subjectsSex differencesClinical disease expressionMale schizophrenic patientsAssociation cortical regionsFemale schizophrenic patientsHealthy female subjectsHealthy male subjectsPathophysiology of schizophreniaVolumetric sex differencesInferior parietal lobuleCortical regionsSchizophrenic subjectsParietal lobuleDisease expressionPatientsSchizophreniaSubjectsMagnetic resonance
1999
Sex Differences in the Inferior Parietal Lobule
Frederikse M, Lu A, Aylward E, Barta P, Pearlson G. Sex Differences in the Inferior Parietal Lobule. Cerebral Cortex 1999, 9: 896-901. PMID: 10601007, DOI: 10.1093/cercor/9.8.896.Peer-Reviewed Original ResearchConceptsInferior parietal lobuleHeteromodal association cortexParietal lobuleGray matter volumeIPL volumesAssociation cortexMatter volumeMale subjectsNeocortical regionsFemale subjectsLeftward asymmetrySubtle cognitive differencesSex differencesLobuleMagnetic resonanceSexual dimorphismFemalesSubjectsSuch sexual dimorphism
1990
Demonstration of naturalistic methods for cocaine smoking by human volunteers
Foltin R, Fischman M, Nestadt G, Stromberger H, Cornell E, Pearlson G. Demonstration of naturalistic methods for cocaine smoking by human volunteers. Drug And Alcohol Dependence 1990, 26: 145-154. PMID: 2242715, DOI: 10.1016/0376-8716(90)90121-t.Peer-Reviewed Original ResearchConceptsVenous blood levelsClinical research unitBlood level curvesFirst doseSubsequent dosesBlood pressureDosing sessionsBlood levelsAcute toleranceCocaine smokingHeart rateDose sessionAscending limbBaseline levelsCardiovascular activityHuman volunteersSubjective effectsTransient increaseResearch volunteersDosesMale research volunteersCocaineVolunteersSubjectsLimbMagnetic resonance imaging evidence for a defect of cerebral cortical development in autism
Piven J, Berthier M, Starkstein S, Nehme E, Pearlson G, Folstein S. Magnetic resonance imaging evidence for a defect of cerebral cortical development in autism. American Journal Of Psychiatry 1990, 147: 734-739. PMID: 2343916, DOI: 10.1176/ajp.147.6.734.Peer-Reviewed Original ResearchConceptsControl subjectsMagnetic resonance imaging (MRI) scansCerebral cortical malformationsResonance imaging scansCerebral cortical developmentAutistic subjectsMigration of neuronsMonths of gestationPathogenesis of autismCerebral cortexCortical malformationsImaging scansCortical developmentMacrogyriaPathogenesisMalformationsAbnormalitiesSubjectsScansMagnetic resonancePolymicrogyriaGestationCortexNeuronsMRI