2022
What can clozapine’s effect on neural oscillations tell us about its therapeutic effects? A scoping review and synthesis
Raymond N, Lizano P, Kelly S, Hegde R, Keedy S, Pearlson G, Gershon E, Clementz B, Tamminga C, Keshavan M. What can clozapine’s effect on neural oscillations tell us about its therapeutic effects? A scoping review and synthesis. Biomarkers In Neuropsychiatry 2022, 6: 100048. DOI: 10.1016/j.bionps.2022.100048.Peer-Reviewed Original ResearchTherapeutic effectNeural oscillationsTreatment-resistant schizophreniaEffects of clozapineElectrical activityRate of seizuresResistant schizophreniaBrain electrical activityClozapinePotential mechanismsSlow wavesSynthesis of findingsSchizophreniaLiterature pertainingHypothesis-driven investigationsReviewElectroencephalogramSeizuresFindingsIndividualsBiomarkers
2018
9.3 PSYCHOSIS BIOTYPES VERSUS CLINICAL SYNDROMES THROUGH THE PRISM OF INTRINSIC NEURAL ACTIVITY
Clementz B, Pearlson G, Tamminga C, Sweeney J, Keshavan M. 9.3 PSYCHOSIS BIOTYPES VERSUS CLINICAL SYNDROMES THROUGH THE PRISM OF INTRINSIC NEURAL ACTIVITY. Schizophrenia Bulletin 2018, 44: s14-s14. PMCID: PMC5888365, DOI: 10.1093/schbul/sby014.031.Peer-Reviewed Original ResearchInter-trial intervalNeural activityIntrinsic neural activityPsychosis biotypesDSM diagnosesSingle-trial powerOngoing neural activityBipolar-Schizophrenia NetworkHealthy personsStimulus salienceNeural responsesNeural oscillationsB-SNIPNeurobiological similaritiesNeurophysiological modelFirst-degree relativesEEG measuresTreatment developmentSensory cortexTranslational research programClinical featuresDistinct physiological mechanismsHealthy groupPsychosis diagnosisPsychosis cases