2024
Relating depressive and manic symptomatology to 1H-MRS spectra
Choquette A, Dager A, Marjańska M, Zatony M, Pearlson G, Glahn D, Knowles E. Relating depressive and manic symptomatology to 1H-MRS spectra. Journal Of Affective Disorders Reports 2024, 16: 100774. DOI: 10.1016/j.jadr.2024.100774.Peer-Reviewed Original ResearchAnterior cingulate cortexN-acetylaspartateRight anterior cingulate cortexAssociated with maniaDepressive symptom scalesSymptom Rating ScaleProfiles of associationDisorder symptomatologyManic symptomsReduced N-acetylaspartateCingulate cortexAffective disordersNeurochemical levelsSymptom ScaleManiaCholine-containing compoundsDichotomous diagnosisMagnetic resonance spectroscopyRating ScalePotential in vivo biomarkersHippocampusIllness etiologyMagnetic resonance spectroscopy dataTotal cholineFollow-up
1988
Manic Syndrome Associated With Zidovudine
Schaerf F, Miller R, Pearlson G, Kaminsky M, Weaver D. Manic Syndrome Associated With Zidovudine. JAMA 1988, 260: 3587-3588. DOI: 10.1001/jama.1988.03410240045016.Peer-Reviewed Original ResearchCases of maniaZidovudine therapySyndrome AssociatedHuman immunodeficiency virus-seropositive individualsAffective disordersImmunodeficiency syndrome dementia complexZidovudine dosageZidovudine treatmentSuch patientsDementia complexManic episodesMajor depressionFamily historyDepressive symptomsCognitive declinePsychiatric syndromesPatientsPersonal historyZidovudineTherapyEt al1ManiaDisordersAssociatedSyndrome
1987
Mania After Brain Injury: A Controlled Study of Causative Factors
Starkstein S, Pearlson G, Boston J, Robinson R. Mania After Brain Injury: A Controlled Study of Causative Factors. JAMA Neurology 1987, 44: 1069-1073. PMID: 3632381, DOI: 10.1001/archneur.1987.00520220065019.Peer-Reviewed Original ResearchConceptsBrain injuryVentricle/brain ratiosPossible family historyFocal brain injurySecondary maniaRight hemisphere lesionsSubcortical atrophyBrain ratioDepressive episodeLimbic areasManic patientsFamily historyManic syndromeFocal lesionsAffective disordersPatientsInjuryLesionsCausative factorsRare occurrenceHemisphere lesionsGenetic loadingRight hemisphereManiaRight hemisphere involvement