1997
Small planum temporale volume in Down's syndrome: a volumetric MRI study
Frangou S, Aylward E, Warren A, Sharma T, Barta P, Pearlson G. Small planum temporale volume in Down's syndrome: a volumetric MRI study. American Journal Of Psychiatry 1997, 154: 1424-1429. PMID: 9326826, DOI: 10.1176/ajp.154.10.1424.Peer-Reviewed Original ResearchConceptsPlanum temporale volumeSuperior temporal gyrusDown syndromeTemporal gyrusSyndrome patientsBrain volumePlanum temporaleMagnetic resonance imaging (MRI) measuresCommunity-dwelling patientsStructural brain abnormalitiesVolumetric MRI studyTotal brain volumeDown syndrome patientsHealthy comparison subjectsWhole brain volumeVolumetric magnetic resonance imaging (MRI) measuresAnatomic substrateBrain abnormalitiesHealthy subjectsComparison subjectsMRI studiesVolume deficitsSyndromeGyrusImaging measures
1996
A Quantitative MRI Study of the Basal Ganglia in Depression in HIV Seropositive Men
Davison S, Aylward E, McArthur J, Selnes O, Lyketsos C, Barta P, Pearlson G. A Quantitative MRI Study of the Basal Ganglia in Depression in HIV Seropositive Men. Journal Of LGBT Health Research 1996, 1: 29-41. PMID: 16873169, DOI: 10.1300/j128v01n03_02.Peer-Reviewed Original ResearchConceptsHIV-seropositive menBasal ganglia volumesBasal ganglia atrophyBasal gangliaMagnetic resonance imagingSeropositive menGanglia volumesHIV infectionHIV-seropositive homosexual menSeropositive homosexual menHIV-seropositive patientsQuantitative MRI studyQuantitative magnetic resonance imagingSeropositive patientsSuch infectionsComparison subjectsMRI studiesHomosexual menAffective disordersDepressive symptomatologyGangliaResonance imagingInfectionSignificant differencesDepression
1988
BRAIN IMAGING WITH IODOAMPHETAMINE (IMP) IN PATIENTS WITH HUNTINGTON'S DISEASE (HD)
LaFrance N, Pearlson G, Folstein S, Cole P, Turek J, Kumar A, Bascom M, McDonald A, Folstein M, Wagner H. BRAIN IMAGING WITH IODOAMPHETAMINE (IMP) IN PATIENTS WITH HUNTINGTON'S DISEASE (HD). Clinical Nuclear Medicine 1988, 13: 392. DOI: 10.1097/00003072-198805000-00039.Peer-Reviewed Original ResearchEarly HD patientsMini-Mental StateHD patientsHuntington's diseaseNeurological examinationMini-Mental State scoresDuration of diseaseGenotype-positive individualsEarly Huntington's diseaseMental state scoresForamen of MonroPotential therapeutic interventionsNormal CTFirst manifestationPositive individualsMRI studiesPatientsPreclinical measuresTherapeutic interventionsIodoamphetamineIMP accumulationDiseaseBrain imagingState scoresSignificant decrement