2021
Anterior-posterior axis of hippocampal subfields across psychoses: A B-SNIP study
del Re E, Zeng V, Alliey-Rodriguez N, Lizano P, Bolo N, Lutz O, Pearlson G, Sweeney J, Clementz B, Gershon E, Tamminga C, Keshavan M. Anterior-posterior axis of hippocampal subfields across psychoses: A B-SNIP study. Biomarkers In Neuropsychiatry 2021, 5: 100037. DOI: 10.1016/j.bionps.2021.100037.Peer-Reviewed Original ResearchVolumetric abnormalitiesPsychosis probandsBipolar type 1Granule cell layerT MRI scansB-SNIP studyB-SNIPDentate gyrusBipolar-Schizophrenia NetworkHealthy controlsClinical dataHippocampal subfieldsDSM categoriesMRI scansSchizoaffective disorderHippocampusType 1Schizophrenia NetworkAbnormalitiesUnaffected relativesAnterior-posterior axisSchizophreniaPsychosisProbandsConclusions Differences
2020
O3.4. PSYCHOSIS PHENOTYPES FROM B-SNIP FOR CLINICAL ADVANCES: BIOTYPE CHARACTERISTICS AND TARGETS
Clementz B, Trotti R, Pearlson G, Keshavan M, Gershon E, Keedy S, Ivleva E, McDowell J, Tamminga C. O3.4. PSYCHOSIS PHENOTYPES FROM B-SNIP FOR CLINICAL ADVANCES: BIOTYPE CHARACTERISTICS AND TARGETS. Schizophrenia Bulletin 2020, 46: s7-s7. PMCID: PMC7234003, DOI: 10.1093/schbul/sbaa028.015.Peer-Reviewed Original ResearchClinical featuresPsychosis biotypesPsychosis casesPsychosis syndromeTreatment targetsSpecific treatment targetsB-SNIPClinical manifestationsBiomarker profilesPsychosis subgroupsB-SNIP consortiumDeep phenotyping approachPathophysiological mechanismsPsychosis patientsBipolar-Schizophrenia NetworkPsychosis diagnosisBiological subtypesHealthy personsClinical practiceClinical advancesNegative symptomsClinical phenomenologySyndromeAuditory paired-stimuli responses across the psychosis and bipolar spectrum and their relationship to clinical features
Parker D, Trotti R, McDowell J, Keedy S, Gershon E, Ivleva E, Pearlson G, Keshavan M, Tamminga C, Sweeney J, Clementz B. Auditory paired-stimuli responses across the psychosis and bipolar spectrum and their relationship to clinical features. Biomarkers In Neuropsychiatry 2020, 3: 100014. PMID: 36644018, PMCID: PMC9837793, DOI: 10.1016/j.bionps.2020.100014.Peer-Reviewed Original ResearchSchizoaffective disorderGroup differencesBipolar disorderAuditory paired-stimulus paradigmPaired-stimulus paradigmNeural responsesIdentification of biomarkersB-SNIPClinical featuresSignificant group differencesPsychosis subjectsBipolar-Schizophrenia NetworkPsychosis casesHealthy subjectsPreparatory periodPsychosis syndromeFrequency principal components analysisMania symptomsP50 responsePositive symptomsClinical phenotypeAffective syndromeBipolar spectrumPsychosisPutative biomarkers
2018
9.3 PSYCHOSIS BIOTYPES VERSUS CLINICAL SYNDROMES THROUGH THE PRISM OF INTRINSIC NEURAL ACTIVITY
Clementz B, Pearlson G, Tamminga C, Sweeney J, Keshavan M. 9.3 PSYCHOSIS BIOTYPES VERSUS CLINICAL SYNDROMES THROUGH THE PRISM OF INTRINSIC NEURAL ACTIVITY. Schizophrenia Bulletin 2018, 44: s14-s14. PMCID: PMC5888365, DOI: 10.1093/schbul/sby014.031.Peer-Reviewed Original ResearchInter-trial intervalNeural activityIntrinsic neural activityPsychosis biotypesDSM diagnosesSingle-trial powerOngoing neural activityBipolar-Schizophrenia NetworkHealthy personsStimulus salienceNeural responsesNeural oscillationsB-SNIPNeurobiological similaritiesNeurophysiological modelFirst-degree relativesEEG measuresTreatment developmentSensory cortexTranslational research programClinical featuresDistinct physiological mechanismsHealthy groupPsychosis diagnosisPsychosis cases