Oral Resolvin D1 attenuates early inflammation but not intimal hyperplasia in a rat carotid angioplasty model
Mottola G, Werlin EC, Wu B, Chen M, Chatterjee A, Schaller MS, Conte MS. Oral Resolvin D1 attenuates early inflammation but not intimal hyperplasia in a rat carotid angioplasty model. Prostaglandins And Other Lipid Mediators 2019, 146: 106401. PMID: 31841663, PMCID: PMC7265259, DOI: 10.1016/j.prostaglandins.2019.106401.Peer-Reviewed Original ResearchConceptsIntimal hyperplasiaResolvin D1Post-operative day 3Phagocytosis activityRat carotid angioplasty modelCAMP levelsLocal inflammatory responsePro-inflammatory genesArterial inflammationCarotid angioplastyOral gavageAcute inflammationVascular injuryThoracic aortaAngioplasty modelEarly inflammationInflammatory responseOral administrationPlasma concentrationsCarotid arteryRvD1Lipid mediatorsAnimal modelsDay 3Inflammation