2001
PREVALENCE OF ANTIBODIES TO HUMAN HERPESVIRUS 8 (HHV-8) IN SAUDI ARABIAN PATIENTS WITH AND WITHOUT RENAL FAILURE1234
Almuneef M, Nimjee S, Khoshnood K, Miller G, Rigsby M. PREVALENCE OF ANTIBODIES TO HUMAN HERPESVIRUS 8 (HHV-8) IN SAUDI ARABIAN PATIENTS WITH AND WITHOUT RENAL FAILURE1234. Transplantation 2001, 71: 1120-1124. PMID: 11374413, DOI: 10.1097/00007890-200104270-00019.Peer-Reviewed Original ResearchConceptsEnd-stage renal diseasePosttransplantation Kaposi's sarcomaPrevalence of antibodiesKaposi's sarcomaHuman herpesvirus 8HHV-8Renal diseaseHerpesvirus 8High incidenceHHV-8-seropositive individualsSmall viral capsid antigenHHV-8 infectionRenal transplant recipientsViral capsid antigenComparison groupArea of residenceSeronegative subjectsESRD patientsSeropositive subjectsTransplant recipientsCapsid antigenSerologic evidenceSeropositive individualsCommon cancerPatients
1998
High Prevalence of Antibodies to Human Herpesvirus 8 in Relatives of Patients with Classic Kaposi's Sarcoma from Sardinia
Angeloni A, Heston L, Uccini S, Sirianni M, Cottoni F, Masala M, Cerimele D, Lin S, Sun R, Rigsby M, Faggioni A, Miller G. High Prevalence of Antibodies to Human Herpesvirus 8 in Relatives of Patients with Classic Kaposi's Sarcoma from Sardinia. The Journal Of Infectious Diseases 1998, 177: 1715-1718. PMID: 9607855, DOI: 10.1086/517429.Peer-Reviewed Original ResearchConceptsSmall viral capsid antigenPrevalence of antibodiesClassic Kaposi's sarcomaHigh incidence areaKaposi's sarcomaActive HHV-8 infectionHuman herpesvirus type 8HHV-8 infectionViral capsid antigenRelatives of patientsHuman herpesvirus 8Familial risk factorsCapsid antigenRisk factorsHigh prevalenceKS patientsHerpesvirus 8SarcomaIncidence areaPopulation agesPatientsVertical transmissionPrevalenceAntibodiesType 8SEROLOGIC ASSOCIATION OF HUMAN HERPESVIRUS EIGHT WITH POSTTRANSPLANT KAPOSI'S SARCOMA IN SAUDI ARABIA1
Wajeh Q, Othman A, Khalid A, Lin3 4, Ren S, Lee H, Ross5 6, Rigsby7 8, Miller3 5. SEROLOGIC ASSOCIATION OF HUMAN HERPESVIRUS EIGHT WITH POSTTRANSPLANT KAPOSI'S SARCOMA IN SAUDI ARABIA1. Transplantation 1998, 65: 583-585. PMID: 9500639, DOI: 10.1097/00007890-199802270-00024.Peer-Reviewed Original ResearchConceptsPosttransplant Kaposi's sarcomaRenal transplant patientsKaposi's sarcomaTransplant patientsSmall viral capsid antigenRenal transplant recipientsTertiary care hospitalViral capsid antigenCross-sectional studyHHV8 antigensSerologic associationsTransplant recipientsRenal failureCare hospitalCapsid antigenCommon cancerControl subjectsSaudi ArabiaSeroreactivity ratesKS patientsSerologic resultsControl groupControl individualsPatientsSarcoma
1996
Antibodies to Butyrate-Inducible Antigens of Kaposi's Sarcoma–Associated Herpesvirus in Patients with HIV-1 Infection
Miller G, Rigsby M, Heston L, Grogan E, Sun R, Metroka C, Levy J, Gao S, Chang Y, Moore P. Antibodies to Butyrate-Inducible Antigens of Kaposi's Sarcoma–Associated Herpesvirus in Patients with HIV-1 Infection. New England Journal Of Medicine 1996, 334: 1292-1297. PMID: 8609946, DOI: 10.1056/nejm199605163342003.Peer-Reviewed Original ResearchConceptsHIV-1-infected patientsEpstein-Barr virusKaposi's sarcomaBC-1 cellsHuman immunodeficiency virus type 1 (HIV-1) infectionVirus type 1 infectionPositive serologic responseHIV-1 infectionType 1 infectionHigh-risk populationAntigen-positive cellsPresence of antibodiesPositive predictive valueEBV antigensKSHV antigensP40 antigenSerologic markersSerologic responseKaposi's Sarcoma-Associated HerpesvirusEtiologic roleSerologic testsPatientsSarcomaPredictive valueKSHV infection
1990
Inhibition of specific binding of EBNA 1 to DNA by Murine Monoclonal and certain human polyclonal antibodies
Orlowski R, Polvino-Bodnar M, Hearing J, Miller G. Inhibition of specific binding of EBNA 1 to DNA by Murine Monoclonal and certain human polyclonal antibodies. Virology 1990, 176: 638-642. PMID: 2161154, DOI: 10.1016/0042-6822(90)90036-q.Peer-Reviewed Original ResearchConceptsEBNA-1 proteinGel mobility shift experimentsMobility shift experimentsSequence-specific DNARecognition of DNAEBNA-1Binding of DNASpecific bindingLac promoterDNA bindingMonoclonal antibodiesDimerization siteSpecific DNANonfusion proteinBurkitt's lymphoma cellsShift experimentsMolecular massEscherichia coliProteinDNASame monoclonal antibodyBindingPolyclonal antibodiesEB virusLymphoma cells
1985
Identification and expression of a nuclear antigen from the genomic region of the Jijoye strain of Epstein-Barr virus that is missing in its nonimmortalizing deletion mutant, P3HR-1.
Rowe D, Heston L, Metlay J, Miller G. Identification and expression of a nuclear antigen from the genomic region of the Jijoye strain of Epstein-Barr virus that is missing in its nonimmortalizing deletion mutant, P3HR-1. Proceedings Of The National Academy Of Sciences Of The United States Of America 1985, 82: 7429-7433. PMID: 2997790, PMCID: PMC391358, DOI: 10.1073/pnas.82.21.7429.Peer-Reviewed Original ResearchConceptsChronic active EBV infectionActive EBV infectionEpstein-Barr virusJijoye strainEBV infectionEBV DNACertain patientsP3HR-1Human antiseraVirus strainsNuclear antigenHr-1JijoyeVirus deletion mutantsLtk- cellsMouse Ltk- cellsImmortalization processPatientsGene transferNeoantigensLymphocytesInfectionAntigenAntibody Responses to Two Epstein-Barr Virus Nuclear Antigens Defined by Gene Transfer
Miller G, Grogan E, Fischer D, Niederman J, Schooley R, Henle W, Lenoir G, Liu C. Antibody Responses to Two Epstein-Barr Virus Nuclear Antigens Defined by Gene Transfer. New England Journal Of Medicine 1985, 312: 750-755. PMID: 2983211, DOI: 10.1056/nejm198503213121204.Peer-Reviewed Original ResearchConceptsChronic active EBV infectionActive EBV infectionEBV infectionNuclear antigenEpstein-Barr virus nuclear antigenEpstein-Barr virus DNAEBV-seropositive subjectsAbnormal immune responseAssociation of EBVNorth African patientsAbsence of antibodiesSuch patientsAfrican patientsSerologic studiesImmune responseNasopharyngeal carcinomaLymphoid cellsPatientsViral gene productsSpecific viral gene productsViral mutationsSerologic reactionsAntigenSerum samplesM antigen
1983
Central-Nervous-System Lymphoma Related to Epstein–Barr Virus
Hochberg F, Miller G, Schooley R, Hirsch M, Feorino P, Henle W. Central-Nervous-System Lymphoma Related to Epstein–Barr Virus. New England Journal Of Medicine 1983, 309: 745-748. PMID: 6310394, DOI: 10.1056/nejm198309293091301.Peer-Reviewed Original ResearchMeSH KeywordsAntibodies, ViralBrain NeoplasmsBurkitt LymphomaDNA, NeoplasmFemaleGenes, ViralHerpesvirus 4, HumanHumansMaleMiddle AgedConceptsEpstein-Barr virusCentral nervous systemSystem lymphomaPrimary lymphomaNervous systemEpstein-Barr virus-specific antibodiesEpstein-Barr virus infectionEpstein-Barr virus genomeRecent primary infectionAdjacent normal brain tissueVirus-specific antibodiesNormal brain tissueSystemic lymphomaBamHI K fragmentAdditional patientsSerologic evidenceOngoing infectionPrimary infectionVirus infectionLymphomaBrain tissueTumor tissueSerum samplesInfectionVirus
1982
Neutralization of lymphocyte immortalization by different strains of Epstein-Barr virus with a murine monoclonal antibody
Miller G, Heston L, Hoffman G. Neutralization of lymphocyte immortalization by different strains of Epstein-Barr virus with a murine monoclonal antibody. Infection And Immunity 1982, 37: 1028-1031. PMID: 6182100, PMCID: PMC347642, DOI: 10.1128/iai.37.3.1028-1031.1982.Peer-Reviewed Original ResearchConceptsEpstein-Barr virusMurine monoclonal antibodiesMonoclonal antibodiesCases of mononucleosisB95-8 strainBurkitt's lymphoma cell linesPolyclonal lymphomaBlood transfusionEBV strainsAmerican patientsChallenge virusLymphoma cell linesBurkitt's lymphomaLymphocyte immortalizationAfrican childrenHybridoma antibodiesAntigenic differencesAntibodiesMarmoset cellsMononucleosisVirusAntigenic sitesCell linesLymphomaAntigen
1980
Diffuse Polyclonal B-Cell Lymphoma during Primary Infection with Epstein–Barr Virus
Robinson J, Brown N, Andiman W, Halliday K, Francke U, Robert M, Andersson-Anvret M, Horstmann D, Miller G. Diffuse Polyclonal B-Cell Lymphoma during Primary Infection with Epstein–Barr Virus. New England Journal Of Medicine 1980, 302: 1293-1297. PMID: 6245364, DOI: 10.1056/nejm198006053022306.Peer-Reviewed Original Research
1976
Infectious Mononucleosis — Epstein–Barr-Virus Shedding in Saliva and the Oropharynx
Niederman J, Miller G, Pearson H, Pagano J, Dowaliby J. Infectious Mononucleosis — Epstein–Barr-Virus Shedding in Saliva and the Oropharynx. New England Journal Of Medicine 1976, 294: 1355-1359. PMID: 177872, DOI: 10.1056/nejm197606172942501.Peer-Reviewed Original ResearchConceptsThroat washingsDuct orificeEpstein-Barr virusDemonstration of virusOropharyngeal sitesInfectious mononucleosisOropharyngeal specimensThird monthIntermittent excretionExcretion patternsAge groupsSecond weekVirusPatientsMonthsOral secretionsSalivaMononucleosisOropharynxExcretionSwabsSecretionWeeks
1974
OROPHARYNGEAL EXCRETION OF EPSTEIN-BARR VIRUS BY RENAL TRANSPLANT RECIPIENTS AND OTHER PATIENTS TREATED WITH IMMUNOSUPPRESSIVE DRUGS
Strauch B, Siegel N, Andrews L, Miller G. OROPHARYNGEAL EXCRETION OF EPSTEIN-BARR VIRUS BY RENAL TRANSPLANT RECIPIENTS AND OTHER PATIENTS TREATED WITH IMMUNOSUPPRESSIVE DRUGS. The Lancet 1974, 303: 234-237. PMID: 4130246, DOI: 10.1016/s0140-6736(74)92546-x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAntibodies, ViralAzathioprineCarrier StateChildChild, PreschoolFemaleFluorescent Antibody TechniqueHerpesvirus 4, HumanHumansImmunity, CellularImmunosuppressive AgentsKidney TransplantationLeukocytesMaleMiddle AgedMouthMucusPharynxPostoperative CarePrednisoneProspective StudiesTherapeutic IrrigationTransplantation, HomologousConceptsEpstein-Barr virusImmunosuppressive drugsRenal homograftsRenal transplant recipientsOropharyngeal excretionShed virusVirus excretorsImmunosuppressive therapySeropositive patientsTransplant recipientsChronic uraemiaThroat washingsVirus 8Seropositive individualsThroat samplesVirus sheddingVirus infectionPatientsNuclear antigenHealthy staffLong-term proliferationDrugsVirusHomograftsTransplantation
1973
Malignant Lymphoma in Cottontop Marmosets after Inoculation with Epstein-Barr Virus
Shope T, Dechairo D, Miller G. Malignant Lymphoma in Cottontop Marmosets after Inoculation with Epstein-Barr Virus. Proceedings Of The National Academy Of Sciences Of The United States Of America 1973, 70: 2487-2491. PMID: 4354852, PMCID: PMC427039, DOI: 10.1073/pnas.70.9.2487.Peer-Reviewed Original ResearchConceptsEpstein-Barr virusMalignant lymphomaImmunosuppressive drugsCottontop marmosetsCell-free Epstein-Barr virusCourse of diseaseCell-free virusHuman malignant lymphomasSarcoma typesVirus antigenAddition of virusLymphomaAutologous cellsTumor formationLatent periodOncogenic capacityOrgan cultureMarmosetsVirusTumorsAntibodiesDrugsAdditional evidenceCellsNeoplasiaProlonged Oropharyngeal Excretion of Epstein–Barr Virus after Infectious Mononucleosis
Miller G, Niederman J, Andrews L. Prolonged Oropharyngeal Excretion of Epstein–Barr Virus after Infectious Mononucleosis. New England Journal Of Medicine 1973, 288: 229-232. PMID: 4345064, DOI: 10.1056/nejm197302012880503.Peer-Reviewed Original ResearchConceptsEpstein-Barr virusThroat washesInfectious mononucleosisEpstein-Barr viral antigensEpstein-Barr virus antibodiesInfectious mononucleosis syndromeUmbilical cord leukocytesOropharyngeal excretionClinical symptomsControl subjectsSerum antibodiesVirus antibodiesViral antigensBlood leukocytesSuch antigensComplement fixationContinuous cell linesFactor presentMononucleosisAntibodiesReference seraPatientsCell linesSyndromeLeukocytes