1990
Differences in the extent of activation of Epstein-Barr virus replicative gene expression among four nonproducer cell lines stably transformed by OriP/BZLF1 plasmids
Gradoville L, Grogan E, Taylor N, Miller G. Differences in the extent of activation of Epstein-Barr virus replicative gene expression among four nonproducer cell lines stably transformed by OriP/BZLF1 plasmids. Virology 1990, 178: 345-354. PMID: 2171186, DOI: 10.1016/0042-6822(90)90331-k.Peer-Reviewed Original ResearchConceptsCell linesEffects of mutationsStable cell linesExtent of activationProtein functionCellular genesGene productsExtrachromosomal plasmidsGene expressionNonproducer cell linesExpression vectorEarly antigenEarly genesGenesLymphoid cell linesCellular subclonesEBV early genesReplicative gene expressionX50-7 cellsZEBRA proteinPlasmidZebraBZLF1 gene productLatent EBVEBV genes
1974
Differences Between Laboratory Strains of Epstein-Barr Virus Based on Immortalization, Abortive Infection, and Interference
Miller G, Robinson J, Heston L, Lipman M. Differences Between Laboratory Strains of Epstein-Barr Virus Based on Immortalization, Abortive Infection, and Interference. Proceedings Of The National Academy Of Sciences Of The United States Of America 1974, 71: 4006-4010. PMID: 4372601, PMCID: PMC434316, DOI: 10.1073/pnas.71.10.4006.Peer-Reviewed Original ResearchConceptsEB virusEarly antigenH virusInitiation of immortalizationAntibody-negative human serumEpstein-Barr virusPretreatment of lymphocytesCell linesHuman umbilical cordDNA synthesisHuman serumInfectious mononucleosisCarrier cell linesBiologic behaviorB95-8Umbilical cordBurkitt's lymphomaLymphocyte immortalizationNonproducer cell linesHuman lymphocytesLaboratory strainsLymphocytesBiologic activityPrimary culturesAbortive infection