1999
Cellular Tropism and Viral Interleukin-6 Expression Distinguish Human Herpesvirus 8 Involvement in Kaposi’s Sarcoma, Primary Effusion Lymphoma, and Multicentric Castleman’s Disease
Staskus K, Sun R, Miller G, Racz P, Jaslowski A, Metroka C, Brett-Smith H, Haase A. Cellular Tropism and Viral Interleukin-6 Expression Distinguish Human Herpesvirus 8 Involvement in Kaposi’s Sarcoma, Primary Effusion Lymphoma, and Multicentric Castleman’s Disease. Journal Of Virology 1999, 73: 4181-4187. PMID: 10196314, PMCID: PMC104197, DOI: 10.1128/jvi.73.5.4181-4187.1999.Peer-Reviewed Original ResearchConceptsViral gene expressionMulticentric Castleman's diseasePrimary effusion lymphomaLevel of expressionCell typesGene expressionViral genesKaposi's sarcomaInfected cell typesLytic cycle viral gene expressionHeterogeneous cell typesCastleman's diseaseInterleukin-6Lytic cycle genesEffusion lymphomaHuman immunodeficiency virus-positive individualsPathogenesis of PELPredominant infected cell typeHuman herpesvirus 8 infectionViral homologueVirus-positive individualsVIL-6B cell growthAltered expressionGenes
1998
A viral gene that activates lytic cycle expression of Kaposi’s sarcoma-associated herpesvirus
Sun R, Lin S, Gradoville L, Yuan Y, Zhu F, Miller G. A viral gene that activates lytic cycle expression of Kaposi’s sarcoma-associated herpesvirus. Proceedings Of The National Academy Of Sciences Of The United States Of America 1998, 95: 10866-10871. PMID: 9724796, PMCID: PMC27987, DOI: 10.1073/pnas.95.18.10866.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceBase SequenceCloning, MolecularDNA PrimersDNA, ComplementaryGene Expression Regulation, NeoplasticGenes, ViralHerpesvirus 4, HumanHerpesvirus 8, HumanHumansMolecular Sequence DataSarcoma, KaposiSequence Homology, Amino AcidTranscription, GeneticTumor Cells, CulturedVirus ActivationConceptsEpstein-Barr virusKaposi's sarcoma-associated herpesvirusSarcoma-associated herpesvirusSmall viral capsid antigenPathogenesis of KSHVLytic cycle gene expressionViral capsid antigenLatent viral genomeCapsid antigenLytic cycle genesInterleukin-6Immediate early genesViral cytokineEarly lytic genesLytic genesHerpesvirusVirusViral genesViral genomeExpressionGene expressionCytokinesPathogenesisCycle genesGenes