Differentiation of Neuro-2a neuroblastoma cells by an antibody to GM3 ganglioside
Chatterjee D, Chakraborty M, Anderson G. Differentiation of Neuro-2a neuroblastoma cells by an antibody to GM3 ganglioside. Brain Research 1992, 583: 31-44. PMID: 1324094, DOI: 10.1016/s0006-8993(10)80007-1.Peer-Reviewed Original ResearchMeSH KeywordsAmino AcidsAnimalsAntibodies, MonoclonalBromodeoxyuridineBucladesineCatecholaminesCell DifferentiationCell DivisionCell LineDNA ReplicationElectrophoresis, Gel, Two-DimensionalElectrophoresis, Polyacrylamide GelFluorescent Antibody TechniqueG(M3) GangliosideGangliosidesKineticsMethionineMiceModels, BiologicalMolecular WeightNeoplasm ProteinsNeuroblastomaSerotoninThymidineConceptsNeuro-2a cellsTotal cellular proteinProtein kinase A (PKA) inhibitorProtein kinase C activityInhibitors of PKCKinase C activityNeuro-2a neuroblastoma cellsCellular proteinsCellular differentiationCell surface gangliosidesElevated intracellular cAMP levelsDifferentiated cellsIntracellular cAMP levelsCyclase activityMode of actionGi proteinsProteinPKCSurface gangliosidesC activityDifferentiationAdenylate cyclase activityNeuroblastoma cellsA inhibitorsGM2 ganglioside