1994
Elevated Cerebrospinal Fluid Levels of Oxytocin in Obsessive-compulsive Disorder: Comparison With Tourette's Syndrome and Healthy Controls
Leckman J, Goodman W, North W, Chappell P, Price L, Pauls D, Anderson G, Riddle M, McSwiggan-Hardin M, McDougle C, Barr L, Cohen D. Elevated Cerebrospinal Fluid Levels of Oxytocin in Obsessive-compulsive Disorder: Comparison With Tourette's Syndrome and Healthy Controls. JAMA Psychiatry 1994, 51: 782-792. PMID: 7524462, DOI: 10.1001/archpsyc.1994.03950100030003.Peer-Reviewed Original ResearchConceptsCerebrospinal fluid levelsObsessive-compulsive disorderCSF oxytocin levelsTourette syndromeArginine vasopressinFamily historyFluid levelsElevated cerebrospinal fluid levelsTic-related obsessive-compulsive disorderOxytocin levelsSubgroup of patientsSubset of patientsElevated CSF levelsCentral arginine vasopressinSubtype of OCDCSF levelsFamily genetic dataHealthy controlsTic disordersForms of OCDPatientsRelated syndromesCurrent severitySyndromeFamily study data
1986
Cerebrospinal fluid monoamine precursor and metabolite levels in children treated for leukemia: Age and sex effects and individual variability
Riddle M, Anderson G, McIntosh S, Harcherik D, Shaywitz B, Cohen D. Cerebrospinal fluid monoamine precursor and metabolite levels in children treated for leukemia: Age and sex effects and individual variability. Biological Psychiatry 1986, 21: 69-83. PMID: 2417634, DOI: 10.1016/0006-3223(86)90009-0.Peer-Reviewed Original ResearchConceptsAcute lymphoblastic leukemiaMetabolite homovanillic acidHomovanillic acidMonoamine precursorsCerebrospinal fluidLevels of HVALumbar cerebrospinal fluidCNS traumaCSF levelsLymphoblastic leukemiaMonoamine systemsCSF samplesChronic effectsSignificant sex differencesMetabolite levelsSignificant correlationLeukemiaSex differencesChildrenIndividual variabilityAgeSex effectsTreatmentLevelsMean coefficient