1986
Bupivacaine for Intercostal Nerve Blocks in Children: Blood Concentrations and Pharmacokinetics.
Rothstein P, Arthur G, Feldman H, Kopf G, Covino B. Bupivacaine for Intercostal Nerve Blocks in Children: Blood Concentrations and Pharmacokinetics. Anesthesia & Analgesia 1986, 65: 625. PMID: 3706800, DOI: 10.1213/00000539-198606000-00011.Peer-Reviewed Original ResearchConceptsIntercostal nerve blockNerve blockBupivacaine concentrationsX minTotal body clearanceVolume of distributionPlasma concentration ratioSteady-state volumeBlood concentration valuesAdult patientsBody clearancePlasma concentrationsBlood concentrationsLocal anestheticsPharmacokinetic evaluationIntercostal spaceBupivacaine HClPharmacokinetic parametersApparent volumeAdditional groupHematocritBupivacaineChildrenClearanceAdultsFate of Left-Sided Cardiac Bioprosthesis Valves in Children
Kopf G, Geha A, Hellenbrand W, Kleinman C. Fate of Left-Sided Cardiac Bioprosthesis Valves in Children. JAMA Surgery 1986, 121: 488-490. PMID: 3954594, DOI: 10.1001/archsurg.1986.01400040126021.Peer-Reviewed Original ResearchConceptsEmergency valve replacementBioprosthetic valvesValve replacementMitral positionBioprosthetic valve failureMassive mitral regurgitationHigh operative mortalityPediatric age groupElective valve replacementYears of agePorcine bioprosthetic valvesLoss of mobilityLeaflet immobilityHospital mortalityOperative mortalityEmergency surgeryHemodynamic deteriorationMitral stenosisSevere calcificationMitral regurgitationBiologic valvesSevere stenosisThromboembolic phenomenaAortic positionMitral valveRepair of Aortic Coarctation in the First Three Months of Life: Immediate and Long-Term Results
Kopf G, Hellenbrand W, Kleinman C, Lister G, Talner N, Laks H. Repair of Aortic Coarctation in the First Three Months of Life: Immediate and Long-Term Results. The Annals Of Thoracic Surgery 1986, 41: 425-430. PMID: 3963920, DOI: 10.1016/s0003-4975(10)62701-4.Peer-Reviewed Original ResearchConceptsVentricular septal defectLong-term resultsNeonatal periodComplex congenital heart lesionsCongenital defectsIsolated ventricular septal defectMultiple ventricular septal defectsGroup IIIOptimum surgical procedurePrimary intracardiac repairPulmonary artery bandingRepair of coarctationGroup of patientsPatent ductus arteriosusLong-term outcomesTreatment of coarctationCongenital heart lesionsLow initial mortalityComplex congenital defectsComplex heart defectsMonths of ageFirst Three MonthsLate deathsRecurrent coarctationInitial hospitalization
1984
Communicating Hydrocephalus Secondary to Superior Vena Caval Obstruction: Occurrence After Mustard's Operation for Transposition of the Great Arteries
Markowitz R, Kleinman C, Hellenbrand W, Kopf G, Ment L. Communicating Hydrocephalus Secondary to Superior Vena Caval Obstruction: Occurrence After Mustard's Operation for Transposition of the Great Arteries. JAMA Pediatrics 1984, 138: 638-641. PMID: 6731381, DOI: 10.1001/archpedi.1984.02140450020006.Peer-Reviewed Original ResearchConceptsCranial enlargementVenous pressureGreat arteriesMustard operationCT scanSuperior vena caval obstructionVena caval obstructionSuperior vena cavaTwo-dimensional echocardiographyHydrocephalus SecondaryIntracardiac baffleVenous obstructionCaval obstructionChest roentgenogramCommunicating hydrocephalusRadiologic cluesAzygous systemVena cavaCSF accumulationSurgical correctionUpper extremityBlood flowSubarachnoid spaceSkull filmsSuperior limb
1983
Aortic Wheeze: Intermittent Tracheal Obstruction Caused by a Rare Aortic Arch Anomaly
Buckwalter J, Hellenbrand W, Sasaki C, Kleinman C, Kopf G, Markowitz R. Aortic Wheeze: Intermittent Tracheal Obstruction Caused by a Rare Aortic Arch Anomaly. Annals Of Otology Rhinology & Laryngology 1983, 92: 383-386. PMID: 6881844, DOI: 10.1177/000348948309200418.Peer-Reviewed Original ResearchConceptsAortic arch anomaliesArch anomaliesTracheal compressionRare aortic arch anomalyEsophageal contrast studyAortic arch interruptionGore-Tex graftArterial ligamentArch interruptionCardiac catheterizationEsophageal compressionSubclavian arterySubclavian stealVertebral arteryTracheal obstructionCarotid arteryContrast studiesArteryAortaDiagnostic importanceBronchoscopySubsequent evaluationDysphagiaCatheterizationStridorOptimal methods of repair of descending thoracic aortic transections and aneurysms
Stavens B, Hashim S, Hammond G, Stansel H, Gatehouse J, Kopf G, Geha A. Optimal methods of repair of descending thoracic aortic transections and aneurysms. The American Journal Of Surgery 1983, 145: 508-513. PMID: 6837888, DOI: 10.1016/0002-9610(83)90049-1.Peer-Reviewed Original ResearchConceptsCross-clamp timeAverage cross-clamp timeGott shuntExtracorporeal circulationThoracic aortic transectionAcute transectionAortic transectionPostoperative bleedingAtherosclerotic aneurysmsTraumatic transectionConsecutive patientsSurgical repairFalse aneurysmSystemic heparinizationThoracic aortaSpinal cordHigh incidenceAcute disruptionSevere injuriesAneurysmsHigh mortalityPatientsTransectionShuntSafe method