1996
Inhibition of Epstein-Barr virus replication by a novel l-nucleoside, 2′-fluoro-5-methyl-β-l-arabinofuranosyluracil
Yao G, Liu S, Chou E, Kukhanova M, Chu C, Cheng Y. Inhibition of Epstein-Barr virus replication by a novel l-nucleoside, 2′-fluoro-5-methyl-β-l-arabinofuranosyluracil. Biochemical Pharmacology 1996, 51: 941-947. PMID: 8651944, DOI: 10.1016/0006-2952(96)00049-4.Peer-Reviewed Original ResearchConceptsEpstein-Barr virus replicationL-FMAUNovel L-nucleoside analogVirus replicationEBV DNA polymeraseMechanism of actionL-nucleoside analoguesEBV agentsPotent inhibitory activityAntiviral activityEBVVirus productionInhibitory concentrationViral productionHuman DNA polymerase alphaSelective inhibitorViral DNAInhibitory activityMetabolism studiesCell growthCellsInhibitionDNA polymerase alphaCellular DNANon-producing cells
1995
Characterization of sublines of Epstein-Barr virus producing HR-1 cells and its implication in virus propagation in culture
Yao G, Tsai C, Cheng Y. Characterization of sublines of Epstein-Barr virus producing HR-1 cells and its implication in virus propagation in culture. Virus Genes 1995, 9: 247-255. PMID: 7597803, DOI: 10.1007/bf01702880.Peer-Reviewed Original ResearchConceptsH sublinesHR-1 cellsZEBRA proteinEBV-specific proteinsHigh EBV DNAEpstein-Barr virusDNA restriction enzyme fragmentsL sublinesEBV polymeraseEBV DNAEBV infectionEBV DNaseEBV proteinsZEBRA expressionEBV productionSodium butyrateSublinesReplication cycleEBVInfectionL cellsDilution methodMolecular characteristicsVirus propagationVirus