S100b Immunoassay: An Assessment of Diagnostic Utility in Minor Head Trauma
Kotlyar S, Larkin GL, Moore CL, D’Onofrio G. S100b Immunoassay: An Assessment of Diagnostic Utility in Minor Head Trauma. Journal Of Emergency Medicine 2010, 41: 285-293. PMID: 20692788, DOI: 10.1016/j.jemermed.2010.05.040.Peer-Reviewed Original ResearchMeSH KeywordsAdultBiomarkersCraniocerebral TraumaEnzyme-Linked Immunosorbent AssayFemaleHead Injuries, ClosedHumansMaleMiddle AgedNerve Growth FactorsProspective StudiesS100 Calcium Binding Protein beta SubunitS100 ProteinsSensitivity and SpecificityYoung AdultConceptsMinor head traumaHead traumaS100B levelsUnited States emergency departmentsMean age 48 yearsMedian S100B levelStates emergency departmentsProspective observational studyGlasgow Coma ScaleAge 48 yearsLoss of consciousnessNon-specific markerReceiver operator characteristic analysisEnzyme-linked immunosorbentOperator characteristic analysisCentral nervous system peptideHCT patientsComa ScaleIntracranial injuryEmergency departmentHead injuryObservational studyUnnecessary headDiagnostic utilityInjury