2013
Hypothermia for aortic surgery
Griepp RB, Di Luozzo G. Hypothermia for aortic surgery. Journal Of Thoracic And Cardiovascular Surgery 2013, 145: s56-s58. PMID: 23410782, DOI: 10.1016/j.jtcvs.2012.11.072.Peer-Reviewed Original ResearchConceptsHypothermic circulatory arrestCirculatory arrestAcceptable neurologic outcomesAortic arch repairThoracoabdominal aortic aneurysmsAortic surgeryNeurologic outcomeArch repairSurgical patientsBrain metabolismOrgan protectionAortic aneurysmDeep hypothermiaClinical practicePig modelRoutine useHypothermiaArrestRepairPatientsSurgeryAneurysmsPerfusionPredicting the Risk for Acute Type B Aortic Dissection in Hypertensive Patients Using Anatomic Variables
Shirali AS, Bischoff MS, Lin HM, Oyfe I, Lookstein R, Griepp RB, Di Luozzo G. Predicting the Risk for Acute Type B Aortic Dissection in Hypertensive Patients Using Anatomic Variables. JACC Cardiovascular Imaging 2013, 6: 349-357. PMID: 23433926, DOI: 10.1016/j.jcmg.2012.07.018.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdultAgedAntihypertensive AgentsAorta, ThoracicAortic AneurysmAortic DissectionAortographyBlood PressureChi-Square DistributionFemaleHumansHypertensionLinear ModelsLogistic ModelsMaleMiddle AgedMultidetector Computed TomographyMultivariate AnalysisPredictive Value of TestsPrognosisReproducibility of ResultsRetrospective StudiesRisk AssessmentRisk FactorsROC CurveConceptsAcute type B aortic dissectionType B aortic dissectionHypertensive patientsB aortic dissectionAAD developmentAortic dissectionAortic archRisk factorsAortic tortuosityAggressive medical managementPre-emptive surgeryOnly risk factorProximal ascending aortaSignificant risk factorsAortic arch diameterStepwise logistic regressionNormotensive patientsAnatomic predictorsEntire aortaMedical managementArtery originAscending aortaTomography angiographyAortic rootAortic imaging
2012
Cerebral Protection for Aortic Arch Surgery: Deep Hypothermia
Di Luozzo G, Griepp RB. Cerebral Protection for Aortic Arch Surgery: Deep Hypothermia. Seminars In Thoracic And Cardiovascular Surgery 2012, 24: 127-130. PMID: 22920529, DOI: 10.1053/j.semtcvs.2011.12.006.Peer-Reviewed Original ResearchConceptsAortic arch surgeryArch surgeryDeep hypothermiaDeep hypothermic circulatory arrestBranched graft techniqueSelective cerebral perfusionTotal arch replacementHypothermic circulatory arrestAortic arch aneurysmArch replacementCerebral protectionArch aneurysmCerebral perfusionCirculatory arrestSurgical outcomesCardiac surgeonsGraft techniqueSurgeryHypothermiaAneurysmsPerfusionSurgeonsTechnical aspectsSelective cerebral perfusion for thoracic aortic surgery: Association with neurocognitive outcome
Uysal S, Lin HM, Fischer GW, Di Luozzo G, Reich DL. Selective cerebral perfusion for thoracic aortic surgery: Association with neurocognitive outcome. Journal Of Thoracic And Cardiovascular Surgery 2012, 143: 1205-1212. PMID: 22306226, DOI: 10.1016/j.jtcvs.2012.01.012.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAorta, ThoracicCardiopulmonary BypassCerebrovascular CirculationChi-Square DistributionCirculatory Arrest, Deep Hypothermia InducedCognitionCognition DisordersFemaleHumansLinear ModelsLogistic ModelsMaleMiddle AgedNeuropsychological TestsNew York CityPerfusionProspective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeVascular Surgical ProceduresConceptsSelective cerebral perfusionHypothermic circulatory arrestSelective cerebral perfusion timeCerebral perfusion timeCardiopulmonary bypass timeThoracic aortic surgeryCerebral perfusionCardiopulmonary bypassCirculatory arrestAortic surgeryBypass timeSurgical patientsNeurocognitive outcomesPerfusion timeHypothermic circulatory arrest timeAortic arch surgeryBrain protection strategiesGroup 3 patientsOptimal brain protectionPostoperative neurocognitive testingGroup 1 patientsGroup 2 patientsThoracic aortic repairCirculatory arrest timeNeurocognitive test scores
2010
Noninvasive cerebral oxygenation may predict outcome in patients undergoing aortic arch surgery
Fischer GW, Lin HM, Krol M, Galati MF, Di Luozzo G, Griepp RB, Reich DL. Noninvasive cerebral oxygenation may predict outcome in patients undergoing aortic arch surgery. Journal Of Thoracic And Cardiovascular Surgery 2010, 141: 815-821. PMID: 20579669, DOI: 10.1016/j.jtcvs.2010.05.017.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAorta, ThoracicBlood Vessel Prosthesis ImplantationCardiopulmonary BypassCirculatory Arrest, Deep Hypothermia InducedCritical CareFemaleFrontal LobeHeart Arrest, InducedHospital CostsHumansLength of StayLogistic ModelsMaleMiddle AgedMonitoring, IntraoperativeNew York CityOximetryOxygenPostoperative ComplicationsPredictive Value of TestsRespiration, ArtificialRisk AssessmentRisk FactorsSeverity of Illness IndexTime FactorsTreatment OutcomeConceptsRegional oxygen saturationAortic arch surgeryArch surgeryOxygen saturationOrgan dysfunctionIntensive care unit lengthRegional oxygen saturation valuesTotal aortic arch replacementPostoperative organ dysfunctionAortic arch replacementExtended hospital staySevere adverse outcomesCerebral oxygenation valuesOxygen saturation valuesArch replacementHemiarch replacementExtubation timeHospital lengthHospital stayPostoperative complicationsCerebral oximetryMinor complicationsConsiderable morbidityMajor complicationsSurgical repairMathematical model for describing cerebral oxygen desaturation in patients undergoing deep hypothermic circulatory arrest
Fischer GW, Benni PB, Lin H, Satyapriya A, Afonso A, Di Luozzo G, Griepp RB, Reich DL. Mathematical model for describing cerebral oxygen desaturation in patients undergoing deep hypothermic circulatory arrest. British Journal Of Anaesthesia 2010, 104: 59-66. PMID: 19933513, PMCID: PMC2791548, DOI: 10.1093/bja/aep335.Peer-Reviewed Original ResearchConceptsDeep hypothermic circulatory arrestHypothermic circulatory arrestCirculatory arrestCerebral desaturationArrest timeMin of DHCACerebral oxygen desaturationAortic arch diseaseArch diseaseAortic surgeryIschemic thresholdNeurological sequelaeOxygen desaturationCerebral oximetryCerebral ischaemiaSurgical treatmentPatient heightPatientsDesaturationArrestMixed modelsX logIschaemiaSequelaeSurgery
2007
Vascular Graft Replacement of the Ascending and Descending Aorta: Do Dacron Grafts Grow?
Etz CD, Homann T, Silovitz D, Bodian CA, Luehr M, Di Luozzo G, Plestis KA, Griepp RB. Vascular Graft Replacement of the Ascending and Descending Aorta: Do Dacron Grafts Grow? The Annals Of Thoracic Surgery 2007, 84: 1206-1213. PMID: 17888971, DOI: 10.1016/j.athoracsur.2007.05.034.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAortaAorta, ThoracicAortic DiseasesBlood Vessel ProsthesisBlood Vessel Prosthesis ImplantationChildCohort StudiesFemaleFollow-Up StudiesHumansMaleMiddle AgedPolyethylene TerephthalatesProbabilityProsthesis DesignProsthesis FailureReoperationRetrospective StudiesRisk AssessmentSurvival RateTreatment OutcomeConceptsDacron graftThoracic aortaGraft expansionPostoperative computed tomography scansAortic valve-sparing proceduresDevelopment of regurgitationDiseased aortic segmentMedian graft diameterRoutine postoperative surveillanceType III endoleakValve-sparing proceduresComputed tomography scanEntire thoracic aortaComputed tomography studyDacron vascular graftsVascular Dacron graftsVascular graft replacementAorta graftThoracoabdominal aneurysmsEndoluminal repairGraft replacementPostoperative surveillanceDescending AortaGraft diameterAortic segments