Force spectroscopy of a single artificial biomolecule bond: The Kramers’ high-barrier limit holds close to the critical force
Husson J, Dogterom M, Pincet F. Force spectroscopy of a single artificial biomolecule bond: The Kramers’ high-barrier limit holds close to the critical force. The Journal Of Chemical Physics 2009, 130: 051103. PMID: 19206951, DOI: 10.1063/1.3077010.Peer-Reviewed Original ResearchConceptsHigh-force regimeHigh barrier limitOptical tweezersEnergy barrierMicron-size beadsKramers approximationBarrier energyForce spectroscopyHigh energy barrierExponential decayEnergy profilesThermal energyEnergyApproximationTweezersBond studyCritical forceRecent modelsDecayKinetics of escapeSpectroscopyKramerRegimeBondsForce