2011
Environmental and Genetic Stressors and the Unfolded Protein Response in Exocrine Pancreatic Function – A Hypothesis
Pandol SJ, Gorelick FS, Lugea A. Environmental and Genetic Stressors and the Unfolded Protein Response in Exocrine Pancreatic Function – A Hypothesis. Frontiers In Physiology 2011, 2: 8. PMID: 21483727, PMCID: PMC3070477, DOI: 10.3389/fphys.2011.00008.Peer-Reviewed Original ResearchProtein responseER stressProtein synthetic machineryUnfolded protein responseDigestive enzymesProtein synthetic capacityRecent findingsAdaptive UPREndoplasmic reticulum stressGenetic stressorsSynthetic machineryMammalian organsEnvironmental stressorsProtein synthesisKey pathwaysUPRReticulum stressExocrine cellsExocrine pancreasSynthetic capacityEnzymePathwayPathologic pathwaysStressorsMachinery
2009
T1834 Role of XBP1 in the Protective Unfolded Protein Response to Limit Chronic Ethanol-Induced Endoplasmic Reticulum Stress and Damage in the Pancreas
Lugea A, Gukovsky I, French S, Gorelick F, Pandol S. T1834 Role of XBP1 in the Protective Unfolded Protein Response to Limit Chronic Ethanol-Induced Endoplasmic Reticulum Stress and Damage in the Pancreas. Gastroenterology 2009, 136: a-589. DOI: 10.1016/s0016-5085(09)62715-3.Peer-Reviewed Original Research