1999
Ejection fraction by radionuclide ventriculography and contrast left ventriculogram A tale of two techniques
Ureña P, Lamas G, Mitchell G, Flaker G, Smith S, Wackers F, McEwan P, Pfeffer M, investigators F. Ejection fraction by radionuclide ventriculography and contrast left ventriculogram A tale of two techniques. Journal Of The American College Of Cardiology 1999, 33: 180-185. PMID: 9935027, DOI: 10.1016/s0735-1097(98)00533-6.Peer-Reviewed Original ResearchConceptsRadionuclide ventriculographyEjection fractionCardiovascular eventsEvent ratesMyocardial infarctionPostinfarct patientsIndependent predictorsRisk stratificationAssess prognosisClinical eventsVentricular performanceClinical impressionPatientsMultivariate analysisPrognosisVentriculographyTercileEF measurementsBest predictorPredictorsComparative abilityCatheterizationInfarctionVentriculograms
1992
Assessment of global and regional left ventricular performance at rest and during exercise after thrombolytic therapy for acute myocardial infarction: Results of the Thrombolysis in Myocardial Infarction (TIMI) II study
Zaret B, Wackers F, Terrin M, Ross R, Weiss M, Slater J, Morrison J, Bourge R, Passamani E, Knatterud G, Braunwald E, Investigators. Assessment of global and regional left ventricular performance at rest and during exercise after thrombolytic therapy for acute myocardial infarction: Results of the Thrombolysis in Myocardial Infarction (TIMI) II study. The American Journal Of Cardiology 1992, 69: 1-9. PMID: 1729855, DOI: 10.1016/0002-9149(92)90667-n.Peer-Reviewed Original ResearchConceptsLV ejection fractionLeft ventricular performanceEjection fractionRegional left ventricular performanceRegional ejection fractionHospital dischargeThrombolytic therapyVentricular performanceTreatment strategiesStrategies patientsComparable work loadNormal exercise responseRegional LV performanceMyocardial Infarction (TIMI) II trialAcute myocardial infarctionHospital-discharged patientsConservative strategyII studyII trialDischarge patientsConservative patientsClinical benefitLV performanceExercise studiesMyocardial infarction
1983
Serial radionuclide assessment of doxorubicin cardiotoxicity in cancer patients with abnormal baseline resting left ventricular performance
Choi B, Berger H, Schwartz P, Alexander J, Wackers F, Gottschalk A, Zaret B. Serial radionuclide assessment of doxorubicin cardiotoxicity in cancer patients with abnormal baseline resting left ventricular performance. American Heart Journal 1983, 106: 638-643. PMID: 6613807, DOI: 10.1016/0002-8703(83)90080-7.Peer-Reviewed Original ResearchConceptsLeft ventricular ejection fractionVentricular ejection fractionCongestive heart failureLeft ventricular performanceVentricular performanceEjection fractionAbnormal baselineHeart failureDoxorubicin therapyDoxorubicin cardiotoxicityRadionuclide angiocardiographyAbnormal left ventricular ejection fractionFinal left ventricular ejection fractionAntecedent cardiovascular diseaseSerial radionuclide studiesFirst-pass radionuclide angiocardiographyIdentification of patientsUse of doxorubicinSafe discontinuationThoracic radiationVentricular functionCancer patientsCumulative doseCardiovascular diseaseRadionuclide assessment
1982
Radionuclide angiographic exercise left ventricular performance in chronic aortic regurgitation: Relationship to resting echographic ventricular dimensions and systolic wall stress index
Lewis S, Riba A, Berger H, Davies R, Wackers F, Alexander J, Sands M, Cohen L, Zaret B. Radionuclide angiographic exercise left ventricular performance in chronic aortic regurgitation: Relationship to resting echographic ventricular dimensions and systolic wall stress index. American Heart Journal 1982, 103: 498-504. PMID: 7064791, DOI: 10.1016/0002-8703(82)90336-2.Peer-Reviewed Original ResearchConceptsChronic aortic regurgitationExercise reserveAortic regurgitationRadius/wall thickness ratioEjection fractionRadionuclide angiocardiographyLV dimensionsEchocardiographic LV dimensionsUpright bicycle exerciseFirst-pass radionuclide angiocardiographyM-mode echocardiographyWall stress indexAR patientsSymptomatic patientsBicycle exerciseVentricular dimensionsVentricular performanceExercise responseExercise performancePatientsEnd systoleEnd diastoleAbsolute changeRegurgitationWall thickness ratioRadionuclide Ventriculography
Wackers F, Berger H, Zaret B. Radionuclide Ventriculography. Developments In Cardiovascular Medicine 1982, 14: 199-233. DOI: 10.1007/978-94-009-7452-4_8.Peer-Reviewed Original ResearchEjection fractionMyocardial infarctFirst acute myocardial infarctLeft ventricular ejection fractionSeattle Heart WatchLeft ventricular dysfunctionCardiac enzyme releaseVentricular ejection fractionCoronary heart diseaseAcute myocardial infarctVentricular dysfunctionPathophysiologic insightsInfarct sizeRadionuclide ventriculographyVentricular performanceVentricular hemodynamicsHeart diseaseMyocardial necrosisValuable predictorEnzyme releaseInfarctsPatientsDirect correlationMorbidityPrognosis
1981
Radionuclide assessment of peripheral intravascular capacity: a technique to measure intravascular volume changes in the capacitance circulation in man.
Rutlen D, Wackers F, Zaret B. Radionuclide assessment of peripheral intravascular capacity: a technique to measure intravascular volume changes in the capacitance circulation in man. Circulation 1981, 64: 146-152. PMID: 6786793, DOI: 10.1161/01.cir.64.1.146.Peer-Reviewed Original ResearchConceptsCapacitance vasculatureVascular capacityIntravascular spaceIntegrated cardiovascular functionIntravascular volume changesGamma camera imagingVenous returnLeg elevationSublingual nitroglycerinVentricular performanceContralateral forearmCardiovascular functionCardiac performanceRadionuclide assessmentBlood volumeRadionuclide imagingPathophysiologic statesPatientsCardiac imagingTwo minutesForearmMenNitroglycerinCountVasculatureSerial radionuclide assessment of doxorubicin cardiotoxicity in cancer patients with abnormal baseline resting left ventricular performance
Choi W, Berger H, Alexander J, Schwartz P, Wackers F, Zaret B. Serial radionuclide assessment of doxorubicin cardiotoxicity in cancer patients with abnormal baseline resting left ventricular performance. The American Journal Of Cardiology 1981, 47: 474. DOI: 10.1016/0002-9149(81)90969-3.Peer-Reviewed Original ResearchExercise left ventricular performance in patients with chest pain, ischemic-appearing exercise electrocardiograms, and angiographically normal coronary arteries.
Berger HJ, Sands MJ, Davies RA, Wackers FJ, Alexander J, Lachman AS, Williams BW, Zaret BL. Exercise left ventricular performance in patients with chest pain, ischemic-appearing exercise electrocardiograms, and angiographically normal coronary arteries. Annals Of Internal Medicine 1981, 94: 186-91. PMID: 7469209, DOI: 10.7326/0003-4819-94-2-186.Peer-Reviewed Original ResearchConceptsNormal coronary arteriesLeft ventricular performanceChest painVentricular performanceCoronary arteryExercise electrocardiogramAbnormal ejection fraction responseMaximal upright bicycle exerciseCoronary arterial spasmUpright bicycle exerciseEjection fraction responseFirst-pass radionuclide angiocardiographyThallium-201 imagingErgonovine testingVentricular dysfunctionArterial spasmBicycle exerciseErgonovine provocationAdditional patientsTreadmill exercisePerfusion defectsRadionuclide angiocardiographyRegional dysfunctionPatientsFraction response
1980
Radionuclide assessment of right and left ventricular exercise reserve after total correction of tetralogy of Fallot
Reduto L, Berger H, Johnstone D, Hellenbrand W, Wackers F, Whittemore R, Cohen L, Gottschalk A, Zaret B, Pytlik L. Radionuclide assessment of right and left ventricular exercise reserve after total correction of tetralogy of Fallot. The American Journal Of Cardiology 1980, 45: 1013-1018. PMID: 7369132, DOI: 10.1016/0002-9149(80)90170-8.Peer-Reviewed Original ResearchConceptsVentricular ejection fraction responseRight ventricular ejection fractionRight ventricular performanceVentricular ejection fractionEjection fraction responseRight ventricular hypertrophyEjection fractionPostoperative patientsVentricular hypertrophyVentricular performanceNormal right ventricular ejection fractionFraction responseThallium-201 myocardial imagingAsymptomatic clinical statusRight ventricular uptakeTotal surgical correctionThallium-201 imagingExercise reserveVentricular uptakeConditions of restClinical statusSurgical correctionRadionuclide angiocardiographyRadionuclide assessmentPatients