2015
Kinetics of Conventional and New Cardiac Radiotracers
Taillefer R, Wackers F. Kinetics of Conventional and New Cardiac Radiotracers. 2015, 58-80. DOI: 10.1093/med/9780199392094.003.0004.Peer-Reviewed Original ResearchMyocardial blood flowDetection of obstructive coronary artery diseaseObstructive coronary artery diseaseBlood flowSympathetic neuronal functionCellular mechanism of uptakeCoronary artery diseaseCardiac imaging protocolImage myocardial perfusionTime of imagingQuantification of regional myocardial blood flowAdjacent organsClinical impactArtery diseaseMyocardial perfusionCardiac imagingCardiac metabolismRegional myocardial blood flowImaging protocolCellular mechanismsNeuronal functionMyocardial extractionCardiac imaging agentMechanism of uptakeImaging agents
1996
Quantitative comparison of single-isotope and dual-isotope stress-rest single-photon emission computed tomographic imaging for reversibility of defects
Siebelink H, Natale D, Sinusas A, Wackers F. Quantitative comparison of single-isotope and dual-isotope stress-rest single-photon emission computed tomographic imaging for reversibility of defects. Journal Of Nuclear Cardiology 1996, 3: 483-493. PMID: 8989673, DOI: 10.1016/s1071-3581(96)90058-6.Peer-Reviewed Original ResearchConceptsDefect reversibilitySingle photon emissionDual-isotope SPECTNormal databaseStress-rest single-photon emissionTechnetium 99m-labeled sestamibiStress-induced myocardial ischemiaStress single-photon emissionPerfusion defect reversibilityPrior myocardial infarctionDefect sizeRest/stressSingle-isotope imagingMyocardial infarctionThallium SPECTMyocardial ischemiaIndividual patientsMyocardial perfusionThallium-201PatientsSestamibiCircumferential count profilesTomographic imagingImaging protocolDual-isotope imaging
1993
Biokinetics of technetium-99m-tetrofosmin: myocardial perfusion imaging agent: implications for a one-day imaging protocol.
Jain D, Wackers FJ, Mattera J, McMahon M, Sinusas AJ, Zaret BL. Biokinetics of technetium-99m-tetrofosmin: myocardial perfusion imaging agent: implications for a one-day imaging protocol. Journal Of Nuclear Medicine 1993, 34: 1254-9. PMID: 8326381.Peer-Reviewed Original ResearchConceptsOrgan ratiosGastrointestinal tractRest imagesImaging protocolSymptom-limited treadmill exerciseDecay-corrected countsLeft anterior oblique viewStress imagesAnterior oblique viewPortion of liverOptimal imaging protocolMyocardial perfusion imaging agentPeak exerciseTreadmill exerciseClinical trialsTechnetium-99mRadiotracer injectionMyocardial perfusionTetrofosmin imagesGallbladderPhase IEntire heartLiverTractOblique view
1992
Comparison of thallium-201 and technetium-99m methoxyisobutyl isonitrile
Wackers F. Comparison of thallium-201 and technetium-99m methoxyisobutyl isonitrile. The American Journal Of Cardiology 1992, 70: e30-e34. PMID: 1442570, DOI: 10.1016/0002-9149(92)90036-x.Peer-Reviewed Original ResearchConceptsThallium-201Coronary artery diseaseComparative clinical trialsSimilar diagnostic yieldSingle photon emissionSymptomatic patientsArtery diseaseMethoxyisobutyl isonitrileNormalcy ratePrognostic significanceViable myocardiumClinical trialsDiagnostic yieldNumerous patientsMyocardial perfusionDiagnostic concordanceImaging protocolClinical applicationPatientsPrognostic proceduresGood specificityTechnetiumAgentsPerfusionMyocardium