1990
Thrombolytic therapy for myocardial infarction: Assessment of efficacy by myocardial perfusion imaging with technetium-99m sestamibi
Wackers F. Thrombolytic therapy for myocardial infarction: Assessment of efficacy by myocardial perfusion imaging with technetium-99m sestamibi. The American Journal Of Cardiology 1990, 66: e36-e41. PMID: 2145744, DOI: 10.1016/0002-9149(90)90610-d.Peer-Reviewed Original ResearchConceptsRecombinant tissue-type plasminogen activatorThrombolytic therapyMyocardial infarctionFirst acute myocardial infarctionInfarct-related artery patencyInitial risk areaPersistent coronary occlusionAcute chest painAcute myocardial infarctionAssessment of efficacyFuture clinical researchImaging agentNew thrombolytic agentsTissue-type plasminogen activatorArtery patencyChest painInfarct arterySuccessful thrombolysisConventional therapyCoronary occlusionHypoperfused myocardiumThrombolytic agentsMyocardial perfusionPatientsEnd pointSerial changes in myocardial perfusion using tomographic technetium-99m-hexakis-2-methoxy-2-methylpropyl-isonitrile imaging following reperfusion therapy of myocardial infarction.
Pellikka P, Behrenbeck T, Verani M, Mahmarian J, Wackers F, Gibbons R. Serial changes in myocardial perfusion using tomographic technetium-99m-hexakis-2-methoxy-2-methylpropyl-isonitrile imaging following reperfusion therapy of myocardial infarction. Journal Of Nuclear Medicine 1990, 31: 1269-75. PMID: 2143527.Peer-Reviewed Original ResearchConceptsReperfusion therapyMyocardial infarctionTc-sestamibiAcute reperfusion therapyFirst myocardial infarctionSuccessful reperfusionTomographic myocardial perfusion imagesSerial changesHypoperfused myocardiumMean decreaseFinal studyMyocardial perfusionPatientsSignificant improvementMyocardial perfusion imagesSecond studyTherapyPerfusion imagesReperfusionInfarctionPerfusionFurther decreaseHrTomographic imagingImaging
1989
Feasibility of tomographic 99mTc-hexakis-2-methoxy-2-methylpropyl-isonitrile imaging for the assessment of myocardial area at risk and the effect of treatment in acute myocardial infarction.
Gibbons R, Verani M, Behrenbeck T, Pellikka P, O'Connor M, Mahmarian J, Chesebro J, Wackers F. Feasibility of tomographic 99mTc-hexakis-2-methoxy-2-methylpropyl-isonitrile imaging for the assessment of myocardial area at risk and the effect of treatment in acute myocardial infarction. Circulation 1989, 80: 1277-1286. PMID: 2530004, DOI: 10.1161/01.cir.80.5.1277.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionMyocardial infarctionThrombolytic therapyTc-sestamibiHypoperfused myocardiumMyocardial perfusionLeft ventricleIntravenous tissue-type plasminogen activatorRegional wall motion scoreIntravenous thrombolytic therapyWall motion scoreTime of administrationEffect of treatmentSingle photon emissionTissue-type plasminogen activatorEjection fractionAnterior infarctsHypoperfused regionsInferior infarctsSimilar injectionsIntravenous injectionMotion scoreInfarctionMyocardial areaInfarct segments