2021
Rates of invasive disease and outcomes in NSCLC patients with biopsy suggestive of carcinoma in situ
Talcott WJ, Miccio JA, Park HS, White AA, Kozono DE, Singer L, Sands JM, Sholl LM, Detterbeck FC, Mak RH, Decker RH, Kann BH. Rates of invasive disease and outcomes in NSCLC patients with biopsy suggestive of carcinoma in situ. Lung Cancer 2021, 157: 17-20. PMID: 34052704, DOI: 10.1016/j.lungcan.2021.05.028.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancerBiopsy suggestiveInvasive diseaseSitu diseaseSquamous histologySurvival outcomesTumor sizeObserved cohortNational Cancer DatabaseExcellent survival outcomesHalf of patientsCell lung cancerMultivariable logistic regressionResection of lesionsAdenocarcinoma histologyDefinitive therapyNSCLC patientsOverall survivalLocal therapyRisk stratificationLung cancerCancer DatabaseResectionSurgical pathologyLesion size
2020
Approach to the Subsolid Nodule
Mase VJ, Detterbeck FC. Approach to the Subsolid Nodule. Clinics In Chest Medicine 2020, 41: 99-113. PMID: 32008632, DOI: 10.1016/j.ccm.2019.11.004.Peer-Reviewed Original Research
2016
Video-assisted thoracic surgery and open chest surgery in lung cancer treatment: present and future
Detterbeck F, Molins L. Video-assisted thoracic surgery and open chest surgery in lung cancer treatment: present and future. Journal Of Visualized Surgery 2016, 2: 173-173. PMID: 29078558, PMCID: PMC5637756, DOI: 10.21037/jovs.2016.11.03.Peer-Reviewed Original ResearchVideo-assisted thoracic surgeryThoracic surgerySimilar long-term survivalEarly-stage lung cancerShorter hospital stayStage lung cancerLung cancer treatmentOpen chest surgeryLong-term survivalHospital staySurgical resectionOpen surgerySurgical approachLung cancerOpen techniqueChest surgeryEffective treatmentLimited incisionTerm survivalSurgeryOpen approachParticular tumorCancer treatmentTreatmentResectionA model for predicting prolonged length of stay in patients undergoing anatomical lung resection: a National Surgical Quality Improvement Program (NSQIP) database study
DeLuzio MR, Keshava HB, Wang Z, Boffa DJ, Detterbeck FC, Kim AW. A model for predicting prolonged length of stay in patients undergoing anatomical lung resection: a National Surgical Quality Improvement Program (NSQIP) database study. Interdisciplinary CardioVascular And Thoracic Surgery 2016, 23: 208-215. PMID: 27073262, DOI: 10.1093/icvts/ivw090.Peer-Reviewed Original ResearchConceptsAnatomical lung resectionProlonged lengthLung resectionRisk factorsRisk stratificationNational Surgical Quality Improvement Program database studyAnatomical pulmonary resectionBetter risk stratificationOverall patient outcomesHigh-risk populationLength of stayExternal validation groupLogistic regression analysisPostoperative complicationsPostoperative variablesPulmonary resectionNSQIP databaseComparison of receiverPatient outcomesDatabase studyResectionPatientsStayValidation groupScoring system
2014
Lung cancer staging: the value of PET depends on the clinical setting
Detterbeck FC, Figueroa Almanzar S. Lung cancer staging: the value of PET depends on the clinical setting. Journal Of Thoracic Disease 2014, 6: 1714-23. PMID: 25589964, PMCID: PMC4283348, DOI: 10.3978/j.issn.2072-1439.2014.11.16.Peer-Reviewed Original ResearchClinical settingEvaluation of patientsInvasive mediastinal stagingPositron emission tomography (PET) imagingEmission Tomography ImagingValue of PETInvasive stagingImpact of PETM1 diseaseN2 diseasePET findingsMediastinal stagingLung cancerRealist synthesis methodResectionClinical contextTomography imagingPatientsRCTsEvaluation of differencesHigher chanceStagingInconsistent resultsDiseaseTraditional imagingTranscervical Wedge Resection After Transcervical Extended Mediastinal Lymphadenectomy
Kim AW, Kull DR, Zieliski M, Boffa DJ, Detterbeck FC. Transcervical Wedge Resection After Transcervical Extended Mediastinal Lymphadenectomy. Innovations Technology And Techniques In Cardiothoracic And Vascular Surgery 2014, 9: 327-329. PMID: 25084246, DOI: 10.1097/imi.0000000000000079.Peer-Reviewed Original ResearchConceptsSame anesthetic settingMediastinal lymphadenectomyWedge resectionM0 adenocarcinomaAnesthetic settingRight upper lobe wedge resectionTranscervical extended mediastinal lymphadenectomyAbsence of lymphPerioperative adverse eventsGround-glass opacitiesExtended mediastinal lymphadenectomyAtypical adenomatous hyperplasiaAdverse eventsLower lobectomyLung resectionCervical approachUpper lobeClinical stageGlass opacitiesLower lobeAdenomatous hyperplasiaPleural spaceResectionLymphadenectomyExcellent accessLearning Curve to Lymph Node Resection in Minimally Invasive Esophagectomy for Cancer
Dhamija A, Rosen JE, Dhamija A, Rothberg BE, Kim AW, Detterbeck FC, Boffa DJ. Learning Curve to Lymph Node Resection in Minimally Invasive Esophagectomy for Cancer. Innovations Technology And Techniques In Cardiothoracic And Vascular Surgery 2014, 9: 286-291. PMID: 25084251, DOI: 10.1097/imi.0000000000000082.Peer-Reviewed Original ResearchConceptsLymph node yieldComplete resectionInvasive esophagectomyNode yieldSurgeon experienceMinimally Invasive EsophagectomyLymph node resectionSingle-surgeon seriesHigh-grade dysplasiaNode resectionComplete lymphadenectomyLymph nodesRetrospective reviewSurgical marginsOncologic efficacyNegative marginsOncologic aspectsInstitutional databaseEsophageal cancerInvasive approachLate subgroupsOpen approachMultivariate analysisResectionSafe alternative
2012
Characteristics Associated With the Use of Nonanatomic Resections Among Medicare Patients Undergoing Resections of Early-Stage Lung Cancer
Kim AW, Detterbeck FC, Boffa DJ, Decker RH, Soulos PR, Cramer LD, Gross CP. Characteristics Associated With the Use of Nonanatomic Resections Among Medicare Patients Undergoing Resections of Early-Stage Lung Cancer. The Annals Of Thoracic Surgery 2012, 94: 895-901. PMID: 22835558, PMCID: PMC3501201, DOI: 10.1016/j.athoracsur.2012.04.091.Peer-Reviewed Original ResearchMeSH KeywordsAge DistributionAgedAged, 80 and overCarcinoma, Non-Small-Cell LungConfidence IntervalsDisease-Free SurvivalEthnicityFemaleHumansLogistic ModelsLungLung NeoplasmsMaleMedicareMultivariate AnalysisNeoplasm InvasivenessNeoplasm StagingOdds RatioPneumonectomyPostoperative ComplicationsPrognosisRetrospective StudiesRisk AssessmentSEER ProgramSex DistributionSurvival AnalysisUnited StatesConceptsChronic obstructive pulmonary diseaseNonanatomic resectionStage I NSCLCSurgical resectionSurgical approachLung cancerNational Cancer Institute's SurveillanceEarly-stage lung cancerPatients 67 yearsPrimary tumor statusObstructive pulmonary diseaseCell lung cancerHospital factorsLung resectionWedge resectionClinical factorsPulmonary diseaseMultivariable analysisTumor sizeLarge tumorsHospital characteristicsTumor statusMedicare patientsResectionPatientsCounterpoint: Are Limited Resections Appropriate in Non-small Cell Lung Cancer? No Don't Overdo It, and Don't Get Confused
Detterbeck FC. Counterpoint: Are Limited Resections Appropriate in Non-small Cell Lung Cancer? No Don't Overdo It, and Don't Get Confused. CHEST Journal 2012, 141: 590-592. PMID: 22396559, DOI: 10.1378/chest.11-3110.Peer-Reviewed Original Research
2011
Long-term survival after lung resection for non–small cell lung cancer with circulatory bypass: A systematic review
Muralidaran A, Detterbeck FC, Boffa DJ, Wang Z, Kim AW. Long-term survival after lung resection for non–small cell lung cancer with circulatory bypass: A systematic review. Journal Of Thoracic And Cardiovascular Surgery 2011, 142: 1137-1142. PMID: 21864854, DOI: 10.1016/j.jtcvs.2011.07.042.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancerCell lung cancerLong-term survivalAdvanced non-small cell lung cancerCirculatory bypassLung cancerLung resectionMultivariate analysisSystematic reviewFavorable long-term survivalUnfavorable long-term survivalWorse long-term survivalCox proportional hazards modelUnplanned cardiopulmonary bypassPrimary end pointKaplan-Meier methodCox regression modelProportional hazards modelPerioperative mortalityExtended resectionCardiopulmonary bypassClinical variablesExclusion criteriaResectionHazards model
2010
Evaluation and Treatment of Stage I and II Thymoma
Detterbeck FC. Evaluation and Treatment of Stage I and II Thymoma. Journal Of Thoracic Oncology 2010, 5: s318-s322. PMID: 20859126, DOI: 10.1097/jto.0b013e3181f20dab.Peer-Reviewed Original ResearchCoping with the unexpected at surgery
Detterbeck FC, Terrien CM. Coping with the unexpected at surgery. Expert Review Of Respiratory Medicine 2010, 4: 115-122. PMID: 20387297, DOI: 10.1586/ers.09.59.Peer-Reviewed Original ResearchConceptsLung cancer surgeryMultidisciplinary tumor boardN2 node involvementPN2 diseaseNode involvementT4 tumorsExperienced centersSuch patientsCancer surgeryPreoperative assessmentTumor boardChest wallBetter outcomesIntraoperative surprisesSurgeryResectionMediastinalPatientsTumorsCareful planningDisease
2008
What to do with “Surprise” N2?: Intraoperative Management of Patients with Non-small Cell Lung Cancer
Detterbeck F. What to do with “Surprise” N2?: Intraoperative Management of Patients with Non-small Cell Lung Cancer. Journal Of Thoracic Oncology 2008, 3: 289-302. PMID: 18317073, DOI: 10.1097/jto.0b013e3181630ebd.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancerMediastinal lymph node dissectionLymph node dissectionMediastinal lymph nodesPositive prognostic factorCell lung cancerAdjuvant therapyNode dissectionLung resectionLymph nodesMalignant involvementPrognostic factorsIntraoperative managementLung cancerPatientsConflicting dataResectionTherapyCancerDiseaseDissectionComprehensive review
2006
Airway Complications After Pulmonary Resection
Farkas EA, Detterbeck FC. Airway Complications After Pulmonary Resection. Thoracic Surgery Clinics 2006, 16: 243-251. PMID: 17004552, DOI: 10.1016/j.thorsurg.2006.05.013.Peer-Reviewed Original ResearchConceptsAirway complicationsPulmonary resectionPrecise surgical techniqueCause of deathConsequent respiratory failureVariety of interventionsBronchial dehiscenceBronchoplastic resectionsLobar torsionEarly reoperationRespiratory failureAspiration pneumoniaPerioperative periodClinical suspicionPostoperative stenosisStump dehiscencePatient populationEarly recognitionSurgical techniqueExtensive dissectionLung parenchymaPleural spaceAnatomic compromiseIndividualized approachResectionSubpleural Catheter Placement for Pain Relief After Thoracoscopic Resection
Detterbeck FC. Subpleural Catheter Placement for Pain Relief After Thoracoscopic Resection. The Annals Of Thoracic Surgery 2006, 81: 1522-1523. PMID: 16564317, DOI: 10.1016/j.athoracsur.2005.01.057.Peer-Reviewed Original Research
2005
Assessment of Real-Time 3D Visualization for Cardiothoracic Diagnostic Evaluation and Surgery Planning
Hemminger BM, Molina PL, Egan TM, Detterbeck FC, Muller KE, Coffey CS, Lee JK. Assessment of Real-Time 3D Visualization for Cardiothoracic Diagnostic Evaluation and Surgery Planning. Journal Of Imaging Informatics In Medicine 2005, 18: 145-153. PMID: 15827827, PMCID: PMC3046705, DOI: 10.1007/s10278-004-1909-2.Peer-Reviewed Original ResearchConceptsDiagnostic evaluationAortic aneurysm repairAirway stent placementPulmonary arteriovenous malformationsCongenital heart defectsLung transplantationAneurysm repairClinical benefitStent placementTumor resectionArteriovenous malformationsRadiological imagingSurgery planningClinical careSurgical planHeart defectsCardiothoracic surgeonsSurgeonsSurgeon confidenceReal-time 3D visualizationRadiology reportsReal-time volume renderingResectionRadiologistsSurgery
2004
Thymic tumors
Detterbeck FC, Parsons AM. Thymic tumors. The Annals Of Thoracic Surgery 2004, 77: 1860-1869. PMID: 15111216, DOI: 10.1016/j.athoracsur.2003.10.001.Peer-Reviewed Original ResearchConceptsComplete resectionThymic tumorsMainstay of treatmentSurvival of patientsIVA thymomaPostoperative radiotherapyThymic carcinomaPreoperative chemotherapyIndolent coursePartial resectionStage IIIResectionThymomaPatientsAggressive behaviorTumorsLittle benefitSuch casesChemotherapyCarcinomaRadiotherapyMainstay
2003
Multifocal right atrial myxoma and pulmonary embolism
Parsons AM, Detterbeck FC. Multifocal right atrial myxoma and pulmonary embolism. The Annals Of Thoracic Surgery 2003, 75: 1323-1324. PMID: 12683591, DOI: 10.1016/s0003-4975(02)04563-0.Peer-Reviewed Original ResearchConceptsPulmonary embolismAtrial myxomaBilateral pulmonary embolismRight heart failureRight atrial myxomaEvidence of recurrencePulmonary arterial flowSurgical resectionHeart failureCardiac myxomaComplete occlusionArterial flowComplete recoveryMyxomaFamilial settingEmbolismRecurrenceResectionDiseaseOcclusionWomen