2016
Role of Adjuvant Therapy for Node-Negative Lung Cancer Invading the Chest Wall
Gao SJ, Corso CD, Blasberg JD, Detterbeck FC, Boffa DJ, Decker RH, Kim AW. Role of Adjuvant Therapy for Node-Negative Lung Cancer Invading the Chest Wall. Clinical Lung Cancer 2016, 18: 169-177.e4. PMID: 27890561, DOI: 10.1016/j.cllc.2016.08.005.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancerAdjuvant chemotherapyAdjuvant chemoradiation therapyUnderwent surgeryChemoradiation therapyChest wall resectionRadiation therapyMargin statusTumor sizeLung cancerWall resectionNode-negative lung cancerNational Cancer Data BaseCox proportional hazards modelMargin-positive patientsChest wall invasionCell lung cancerLog-rank testStage IIB tumorsProportional hazards modelAdjuvant therapyAdjuvant treatmentOverall survivalMultivariable analysisIIB tumors
2015
Evaluating the fate of patients who undergo resections of very large, node-negative lung cancers using the National Cancer DataBase
Liu J, Hancock JG, Moreno AC, Wang Z, Boffa DJ, Detterbeck FC, Kim AW. Evaluating the fate of patients who undergo resections of very large, node-negative lung cancers using the National Cancer DataBase. European Journal Of Cardio-Thoracic Surgery 2015, 49: 596-601. PMID: 25890936, DOI: 10.1093/ejcts/ezv139.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAdultAgedAged, 80 and overCarcinoma, Non-Small-Cell LungCarcinoma, Squamous CellChemoradiotherapy, AdjuvantDatabases, FactualFemaleFollow-Up StudiesHumansLung NeoplasmsLymph NodesMaleMiddle AgedNeoadjuvant TherapyNeoplasm StagingPneumonectomyRetrospective StudiesSurvival AnalysisTreatment OutcomeTumor BurdenUnited StatesConceptsPostoperative radiation therapyNational Cancer DatabaseNeoadjuvant chemoradiation therapyAdjuvant chemoradiation therapyChemoradiation therapyAdjuvant chemotherapyOverall survivalSurgical therapyLung cancerCancer DatabaseNode-negative lung cancerImproved OS relativeLymph node involvementKaplan-Meier methodCell lung cancerCox regression modelFate of patientsLog-rank testDifferent treatment modalitiesOS relativeNode involvementMetastatic diseaseSurgical resectionLymph nodesOS ratesBolstering the Case for Lobectomy in Stages I, II, and IIIA Small-Cell Lung Cancer Using the National Cancer Data Base
Combs SE, Hancock JG, Boffa DJ, Decker RH, Detterbeck FC, Kim AW. Bolstering the Case for Lobectomy in Stages I, II, and IIIA Small-Cell Lung Cancer Using the National Cancer Data Base. Journal Of Thoracic Oncology 2015, 10: 316-323. PMID: 25319182, DOI: 10.1097/jto.0000000000000402.Peer-Reviewed Original ResearchConceptsSmall cell lung cancerNational Cancer Data BaseSurgical resectionStage ISCLC patientsSublobar resectionOverall survivalLung cancerIIIA small cell lung cancerFive-year overall survivalAddition of surgeryClinical stage IPatient underwent surgeryPrimary surgical resectionKaplan-Meier methodLikelihood of deathCurative intentComorbidity scoreUnderwent surgeryChemoradiation therapyHazard ratioMetastatic diseaseMultimodality treatmentSelect patientsTreatment regimen
2013
Pulmonary resections following prior definitive chemoradiation therapy are associated with acceptable survival
Kuzmik GA, Detterbeck FC, Decker RH, Boffa DJ, Wang Z, Oliva IB, Kim AW. Pulmonary resections following prior definitive chemoradiation therapy are associated with acceptable survival. European Journal Of Cardio-Thoracic Surgery 2013, 44: e66-e70. PMID: 23557918, DOI: 10.1093/ejcts/ezt184.Peer-Reviewed Original ResearchConceptsDefinitive chemoradiation therapySalvage lung resectionChemoradiation therapyLung resectionPostoperative survivalCurative-intent chemoradiation therapyMultivariate Cox proportional modelMedian disease-free intervalLung cancer resectionRecurrent lung cancerDisease-free intervalCox proportional modelsLung cancer recurrenceDefinitive chemoradiationPerioperative deathsSalvage resectionComplication ratePulmonary resectionCancer resectionDefinitive treatmentImproved survivalLung cancerCancer stageMedical recordsCancer recurrence